简介:美国国家眼科研究所陈之昭教授主编的《眼科疾病的动物模型》中文版由陈大年和魏来教授翻译,将于2016年春由人民卫生出版社出版。该书是最新的关于眼病动物模型的专著,由各领域顶级专家撰写,附有国际顶尖眼科医生的评价,是连接临床和基础研究的桥梁。
简介:在场的AIMTo为在一个兔子model.METHODSA兔子绿内障动物模型的环绕的canaloplasty的新、简单、便宜Schlemm运河microcatheter被triamcinoloneacetonide的intravitreal注射建立。有新Schlemm运河microcatheter的环绕的canaloplasty(专利许可证数字:201220029850.0)被执行。Schlemm运河microcatheter由microcatheter墙和腔组成。墙用高折射的索引塑料做的能被纳入的光纤维一发光以便整个点亮的microcatheter在环绕的canaloplasty期间是可见的。腔能为注射被纳入一个注射者在catheterization期间粘弹性。兔子随机被划分成控制,模型和处理组。Intraocular压力(IOP)与Tono钢笔音调测定器操作前被测量并且3,7,14,21并且28d操作以后。超声biomicroscopy被执行在Schlemm运河设想Schlemm运河microcatheter,巩膜pool.RESULTSTheSchlemm运河microcatheter能被用来在兔子绿内障动物模型执行环绕的canaloplasty。IOP在模型组比那在处理组是更低的3,7,14并且在操作以后的28d。在在控制组和处理组之间的IOP没有重要差别。在三个组之中的差别是统计上重要的(3d:F=41.985,P<0.001;7d:F=65.696,P<0.001;14d:F=114.599,P<0.001;28d:F=55.006,P<0.001).CONCLUSIONCircumferentialcanaloplasty控制在兔子的试验性的绿内障模型安全、有效。
简介:AIM:Toinvestigatetheeffectsofanewopeningpatterninneodymium:yttrium-aluminum-garnet(Nd:YAG)laserposteriorcapsulotomyonvisualfunction.METHODS:Thistechniquewasconductedalongacircularpattern.Theenergyrangedbetween0.8and1.2mJ/pulsewasconsumedandmeantotalenergylevelswere74±21mJ(mean±standarddeviation:SD,from40to167)andlasershotsaimedat150μmawaybehindadatumpointandwentalonganimaginarylinewhichextends0.5mminsidefromopticmarginandintothecircularenblocpattern.Vitreousstandswereattachedwithfragmentandthentheywerecutoffbythelaseraftercircularapplication.Thecircularfragmentwascompletelyseparatedfromvitreous,andthenthisfragmentwasquicklysunkinintravitrealspace.RESULTS:Thefollow-upperiodrangesfromatleastaweekto40mo,making15.8moonaverage.Theproceduraloutcomeshowed96%(74eyesoutofthe77eyes)enhancementinpatients’visualacuity.Cystoidmacularedemaorretinaldetachmentwasnotobservedinanyofthepatientsduringfollow-upperiods.CONCLUSION:Thisnewtechniqueisexpectedtoimprovetheweaknessesthattheconventionalprocedureshavebyaddingtheprocesstocutoffvitreousstandsattachedwiththefragmentbythelasertothecircularapplication.
简介:DearEditor,IamDr.SorayaMediero,fromDepartmentofOphthalmologyofLaPazUniversityHospital,Madrid,Spain.IwritetopresentacasereportofkeratoconusassociatedwithWilliams-Beurensyndrome(WBS).Toourknowledge,thisisthefourthreportofkeratoconusassociatedwithWBSandthe
简介:CornealdiseasesarecurrentlythesecondmaincauseofblindnessinChina.Althoughmostofthecornealblindnesscouldbetreatedbycornealtransplantation,onlyabout10000operationswerecarriedouteachyearowingtothesevereshortageofcornealdonorsandlimitedeyebankprograms.AfeasiblecorneadonationprogramwasestablishedthroughtheorganizationoftheRedCross,andinsitucornealremovaltechniquesweredevelopedtoavoidconflictswithChinesetraditionsofkeepingthedeceasedintact.Thenumberofdonatedcorneas,whichhadasafeandsecurequality,increasedsignificantlyyearbyyear.