简介：AIMTo与反弹tonometry(RBT)调查成年畿尼猪眼睛的intraocular压力(IOP)，并且估计包括Carteolol减少药的四特殊热门IOP的效果，Brimonidine，24头12-week-old畿尼猪(48只眼睛)的Brinzolamide和Latanoprost.METHODSTheIOP每二个小时作为基线与RBT一天内被测量。所有动物然后被划分成四个组(Carteolol，Brimonidine，Brinzolamide和Latanaprost组织，n=6)。IOP被测量并且与基线相比1，2，3，5，7，9，15并且在24头畿尼猪(48只眼睛)的treatment.RESULTSThe平均数基线IOP以后的24h是10.3GSH试金工具包。Akt1和Aktphosphorylation(p-Akt1)层次被西方的弄污测量，immunofluorescence.RESULTSAA在高集中导致了毒性并且显著地在20的集中刺激了HCEC的增长

简介：neovascularization的形成是许多眼睛的脉管的疾病的一个普通病理学的特征，并且是在病人的视觉损失的一个重要原因。Neovascularization能引起网膜的出血，玻璃的出血，和另外的严肃的复杂并发症，导致视觉的损失。intraocularneovascularization的治疗是眼科学研究的焦点。在最近的年里，一些研究发现了autophagy是仔细与脉管的endothelial生长因素和neovascularization的形成有关。Autophagy被期望为intraocularneovascularization的治疗成为一个新目标。因此，这篇文章在autophagy和intraocularneovascularization的形成上考察研究。

简介：Amodifiedrelationbetweentheintraocularandintracranialpressuresispresentedbyemployingtheleastsquaremethodtofittheexistingexperiments.Relativeanalysishereindicatesthatthismodifiedrelationnotonlyisbetterthanthepreviousrelationbycomparingwiththeexistingexperimentaldatabutalsoovercomestheinducedsingularityinapplyingtheexistingmechanicalmodelstocomputethemechanicalpropertiesofthelaminacribrosa.Thepresentstudywillbeabeneficialhelptounderstandingtherelationshipbetweentheintraocularandintracranialpressuresandevenglaucomatousdeveloping.

简介：AIMTo把视觉功能的结果与提供和回顾的比较学习包括了的multifocalintraocular透镜(IOL).METHODSOur作比较51个病人(60只眼睛)收到了提供的IOL的培植(Tetraflex；16个病人，20只眼睛)，折射multifocalIOL(重新激增；18个病人，20只眼睛)，或绕射的multifocalIOL(ZMA00；17个病人，20只眼睛)。在在三的球形的等价物组织的surgery.RESULTSThe是-0.38???????迱需?韘?韘以后，主观折射，视觉尖酸，对比敏感(CS)，intraocular错误，和主观光斩的现象在3mo被检测吗？？

简介：

简介：Inthisstudy,thepolyacrylateintraocularrlensisirradiatedbyargonionwhichcanproducefreeradicals.Inordertoobtainbetterhydrophilicandlowerplateletsadhesion,monomervinylpyrrolidone(NVP)isgraftedontothehydrophobicpolyacrylateintraocularlenssurfaceinacertainreactionconditions.Specificchangesinintraocularlensaredetectedbystaticcontactangle(CA),scanningelectronmicroscope(SEM)andlighttransmittance.Theresultsshowthatthissurfacemodificationcangreatlyimproveitshydrophiliccharacterandsurfaceformation.

简介：Topreventthecomplicationsincataractsurgeries,theeyesofrabbitsandmonkeyswereimplantedwithintraocularlensfor360days.Methods:Theeyesoftherabbitswereperformedwithphacoemulsificationandsoftintraocularlensimplantation.Theeyesofthemonkeyswereperformedwithextracapsularcataractextractionandhardintraocularlensimplantation.Results:Thepostoperativereactionsincludedcornealedema,anteriorchamberexudation,posteriorcapsuleopacificationandsoon.Thecomplicationsintheeyesoftherabbitsweremorethanthatintheeyesofthemonkeys.Conclusion:Thedifferentpostoperativereactionshappenedindifferentanimals.Inclinicalthechoiceoftheoperativemethodandintraocularlensdependedonthecaseinordertoacquirethebestsight.

简介：<正>DearSir,Oculartraumaisatopicofunresolvedcontroversiesandtherearecontinuouscontroversialanddebatablediagnosticandmanagementstrategiesforopen-globeinjuries[1].Amongstmanytypesofoculartrauma,theopenglobeinjuryisthemostseriousduetoitsverypoorvisualprognosisandyoungpopulationofpatientsaremostlyaffected[2].Thetreatmentoutcomemaybeimprovedbypromptdiagnosis,andimmediatesurgicalrepairperformedtohighstandard[3].Amongsttheotherclinicalsignstheintraocularpressure(IOP)isfoundtobeparticularlyreducedandconventionallythisisconsideredasaveryreliableindicatorofoccultglobe

简介：AIM:Tosystematicallyreviewwhethertheincreasedfluctuationofintraocularpressure(IOP)isariskfactorforopenangleglaucoma(OAG)progression.METHODS:ScientificstudiesrelevanttoIOPfluctuationandglaucomaprogressionwereretrievedfromMEDLINE,EMBASEandCENTRALdatabases,andwerelistedasreferencesinthispaper.Thehazardratio(HR)wascalculatedbyusingfixedorrandom-effectsmodelsaccordingtotheheterogeneityofincludedstudies.RESULTS:Individualdatafor2211eyesof2637OAGpatientsinfourteenprospectivestudieswereincludedinthisMeta-analysis.Allstudieswerelongitudinalclinicalstudieswithfollow-upperiodrangingfrom3to8.5y.ThecombinedHRwas1.23(95%CI1.04-1.46,P=0.02)fortheassociationbetweenIOPfluctuationandglaucomaonsetorprogressionwiththeevidenceofheterogeneity(P<0.1).SubgroupanalyseswithdifferenttypesofIOPfluctuationwerealsoevaluated.ResultsindicatedthatthesummaryHRwas0.98(95%CI0.78-1.24)inshort-termIOPfluctuationgroup,whichshowednostatisticalsignificancewithheterogeneity,whereas,thecombinedHRwas1.43(95%CI1.13-1.82,P=0.003)inlong-termIOPfluctuationgroupwithouthomogeneity.SensitivityanalysisfurthershowedthatthepooledHRwas1.10(95%CI1.03-1.18,P=0.004)forlong-termIOPfluctuationandvisualfunctionprogressionwithhomogeneityamongstudies(P=0.3).CONCLUSION:Long-termIOPfluctuationcanbeariskfactorforglaucomaprogressionbasedonthepresentedevidence.Thus,controllingtheswingofIOPiscrucialforglaucomaorglaucomasuspectingpatients.

简介：在在IOP上调查了triamcinoloneintravitrealtriamcinoloneacetonide的注射的效果的研究的triamcinoloneacetonide.METHODSSystematic文学评论的intravitreal注射以后的intraocular压力(IOP)上的AIMTo报告根据Cochrane合作方法论被进行，报导效果被分析了，Meta-analysis.RESULTSWe发现了IOP跟随inverted-U随着时间的过去以14.81±的平均价值开始的形状模式；1.22而且，学习的土地，变老，绿内障和性作文物质为的以前的历史跨学习在报导IOPchanges.CONCLUSIONOur调查结果是不同的可能在象象反脉管的endothelial生长因素代理人那样的更最近的治疗把它与那些作比较一样决定intravitrealtriamcinoloneacetonide治疗的压力举起风险有用。

简介：AIM:Toevaluatetheefficacy,safetyandstabilityofposteriorchamberphakicintraocularlensimplantationforthecorrectionofhighmyopia.METHODS:Retrospectivecasereviewof82eyes(43patients)undergoingimplantableColiamerlens(ICL)placementbyasinglesurgeon(Xiao-WeiGao)tocorrectpreoperativemeansphericalequivalentsbetween-9.00diopter(D)and-23.00D.Mainoutcomemeasuresincludeduncorrectedvisualacuity(UCVA),refraction,bestspectacle-correctedvisualacuity(BSCVA),endothelialcelldensity(ECD),intraocularpressure(IOP),lenstransparency,postoperativeuveitis.Visanteanteriorsegmentopticalcoherencetomography(AS-OCT)wasusedtomeasureanteriorchamberdepth(ACD)andthepositionofICL.RESULTS:Meanfollow-upwas6.54±3.26months(range3-12months).Predictabilityofthemanifestsphericalequivalent(SE)refractiontowithin±1.OODwasachievedin88%ofeyesand±0.50Din72.5%ofeyes.ThemeanpostoperativemanifestSErefractionwas-1.85±0.72D,with96.34%ofeyesmaintainingorgaining≥1line(s)ofBSCVA.Themean3-monthpostoperativeECDdecreasedbuthadnostatisticallydifferencecomparedwiththepreoperativeECD.Ofthe7eyes(8.54%)withamildtransientincreaseinintraocularpressure(upto30mmHg),nonerequiredasecondsurgicalprocedureorprolongedtopicalmedication.Therewasnolossoflenstransparency.Pigmentedprecipitateswereobservedin5eyes(6.09%).ThemeanpreoperativeACDmeasuredwithAS-OCTwas3.28±0.14mm,threemonthsaftersurgery,themeanACDwas2.45±0.22mm.Anteriorchamberdepthshowedastatisticallysignificantreduction.Oneeye(1.22%)hadICLspontaneousrotation,81eyes(98.78%)ofthelensremainedcorrectlycentered.CONCLUSION:TheimplantationofICLisaneffectivesurgicaloptionforthemanagementofhighmyopia.Butitslongtimeeffectandsafetystillneedmoretimetoprove.

简介：

简介：AIM:ToperformaMeta-analysistoexplorethecorrelationbetweenmetabolicsyndromeandintraocularpressure(IOP).METHODS:WesearchedPubMedandEmbaseinNovember2017forstudiesdiscussingtherelationshipbetweenmetabolicsyndromecomponentsandIOPinpatients.Pearsoncorrelationcoefficients,oddsratiosandstandardizedbetaswereextractedfrominclusivestudies.Heterogeneityandpublicationbiaswerechecked.RESULTS:Of295articles,10metinclusioncriteriaandprovidedsufficientdataforMeta-analysis.ResultsshowedasignificantpositiverelationbetweenmetabolicsyndromeandIOP(Z=0.47,95%CI:0.15-0.79,P=0.005).Thefivecomponents[waistcircumference,hypertriglyceridemia,highbloodpressure,highfastingglucoseandlowhighdensitylipoprotein(HDL)-cholesterol]ofmetabolicsyndromeallshowedpositivecorrelationwithIOPexceptthelowHDL-cholesterolwhichhadnostatisticalsignificance.ThepooledZwas0.08(95%CI:0.04-0.12),0.16(95%CI:0.11-0.21),0.16(95%CI:0.10-0.22),0.30(95%CI:0.20-0.40)and0.12(95%CI:0.08-0.16),respectively.Begg’stestandEgger’stestshowednoevidenceofsignificantpublicationbiasofthisMeta-analysis.CONCLUSION:OurfindingssuggestthatmetabolicsyndromeanditscomponentsaresignificantlyassociatedwithIOP,besidestheHDL-cholesterol.ThisassociationmaybeusedtocontrolIOPbyinterveningtheoccurrenceofmetabolicsyndrome.

简介：AIMTo在intraocularscattering.METHODSSixty上在小切口的lenticule抽取(微笑)和它的效果以后调查帽子形态学--经历微笑的33个病人的五只眼睛被注册。除了常规评估，Fourier域光连贯断层摄影术被用来在1d调查帽子厚度，1wk，1并且3mo手术后地。散布的光优秀包括调整转移函数截止频率，Strehl比率，光优秀分析系统(OQAS)值，和目的索引(OSI)，用OQAS.RESULTSCap厚度被评估从1d减少了到1wk(P<0.001)，但是仍然保持比120的打算的厚度高

简介：AIM:Toutilizetissuemicromeasurementtostudytheeffectoftransienthighintraocularpressure(IOP)inducedbydifferentdurationsofsuctionduringlaserinsitukeratomileusis(LASIK)onrabbitretinathickness.·METHODS:SixtyhealthyNewZealandwhiterabbitswererandomlydividedintoacontrolgroup,and3negative-pressuresuctiongroups(20sgroup,45sgroup,and3mingroup)andeachgroupwascomprisedof15rabbits(30eyes);thelatter3groupswerethetransienthighIOPmodels.Theretinaltissuearoundthepapilledemawasseparated.Hematoxylinandeosin(HE)stainingwascarriedouttogenerateslicesforlightmicroscopy.Thechangesintheretinathicknessvaluesofeachlayerweremeasuredforallanimalsineachgroupatdifferentpostoperativerecoveryperiodsandcomparedwiththevaluesrecordedfortheanimalsinthecontrolgroup.Thethicknessoftheretinaltissueshowedanormaldistribution.TheANOVAwasperformedbyusingSPSS13.0statisticsoftware.·RESULTS:Inthecomparisonbetweenthe20sand45snegative-pressuresuctiongroupsandthecontrolgroup,nosignificantdifferenceswereobserved,exceptat14d.Significantdifferencewasobservedbetweenthe3minnegative-pressuresuctiongroupandthecontrolgroup,andtheretinathicknessvalueofeachlayerreachedapeakat14dafterrepair.·CONCLUSION:Conv

简介：<正>DearSir,IamDr.YunLi,fromtheSecondHospitalAffiliatedtoNanchangUniversity,JiangxiProvince,China.IwritetopresentacasereportofIOLimplantationin

简介：AIMTo调查在植入与的病人与光斩的现象联系的独立因素折射，旋转地不对称，multifocalintraocular透镜(MIOL).METHODSThirty--经历了单方的奔流外科的34个病人的四只眼睛，由旋转地不对称的MIOL的培植列在后面被包括。距离和近视觉的尖酸结果，intraocular错误，比较喜欢的读物距离，外科手术前、手术后的折射错误，mesopic和photopic学生直径，和mesopic和photopickappa角度被估计。病人们也被管理满足调查。光斩的现象被问询表分级。独立人士相关的因素被关联和bivariate识别到mesopic学生中心(学生中心移动)的从photopic的逻辑回归analyses.RESULTSThe距离显著地与瞪视/光圈症状被联系[机会比率(或)=2.065，95%信心间隔(CI)=0.916-4.679，P=0.006]并且夜里视觉问题(OR=1.832，95%CI=0.721-2.158，P=0.007)。外科手术前的photopic角度kappa显著地与瞪视/光圈症状被联系(OR=2.155，95%CI=1.065-4.362，P=0.041)。photopic角度kappa显著地也与瞪视/光圈症状被联系(OR=2.155，95%CI=1.065-4.362，P=0.041)并且与夜里视觉问题(OR=1.832，95%CI=0.721-2.158，P=0.007)在与旋转地不对称的MIOLs.CONCLUSIONA植入的病人，在视觉、学生的轴(角度kappa)之间的大学生中心移动和错误排列可以在旋转地不对称的MIOL的培植以后在光斩的现象的出现起一个作用。

简介：AIMTo评估剥去与在没有胶囊的support.METHODSDSAEK的严重地损坏的眼睛的透镜(IOL)培植与工匠虹爪IOL培植相结合的工匠缺少晶状体intraocular相结合的自动化endothelialkeratoplasty(DSAEK)的descemet的复杂并发症和结果在29只眼睛上被执行。所有眼睛由于从优先的intraocular手术和眼睛的损伤的复杂并发症具有反常结构。眼睛的复杂并发症观察了包括的接枝脱臼，高intraocular压力(IOP)，IOL脱臼，有斑点的浮肿和hyphema。最好改正的视觉尖酸(BCVA)，IOP和吝啬的中央endothelial房间密度(ECD)是有的recorded.RESULTSThirteen眼睛眼睛的损伤的历史，10只眼睛有前面的房间IOL，16只眼睛有优先的vitrectomy。虹在22种情况中是反常的。接枝脱臼发生在5(17.2%)29只眼睛。IOL脱臼发生在2只眼睛(6.9%)。高IOP在9只眼睛被发现并且与处理被控制。外科手术前的吝啬的BCVA是20/286。6mo手术后的吝啬的BCVA是20/42。平均中心ECD是在6mo的1965.3房间/公里2，并且施主房间损失的率是与工匠缺少晶状体IOL培植相结合的34.7%.CONCLUSIONDSAEK是为没有胶囊的支持，在aphakic眼睛解决endothelial和透镜混乱的一种其他的选择。然而，它应该与严重的虹缺点为眼睛小心地被执行。

简介：AIMTo比较特征预装，在IOL交货procedures.METHODSTotal期间，101人看的非预装的intraocular透镜(IOL)交货系统在这个未来的观察盒子系列被包括。包括iSert250NC60(NC60)的IOL的5种类型的交货特征，EnVistaMX60(MX60)，AcrySofIQSN60WF(SN60WF)，TECNISZCB00(ZCB00)，和TECNISPCB00(PCB00)被调查。NC60和PCB00经由预装的交货系统被注射，另外的IOL经由非预装的系统被注射。在人的试用，从装载到培植的结束的IOL花的时间在经历常规奔流外科的所有眼睛被测量。用4只切除猪的眼睛，在一个IOL注射者和一只猪的眼睛之间的眼的viscosurgical设备(OVD)的动力学用IOL培植的染色钠的OVD.RESULTSThe平均时间是的荧光黄被分析为NC60，为MX60的43.2年代，为SN60WF的32.3年代，为ZCB00的41.4年代，和为PCB00的14.6年代的22.0年代分别地。有有第二台仪器的IOL操作的案例的数字为MX60是6，2为ZCB00，0为SN60WF，NC60，和PCB00。推进一只猪的眼睛的OVD的数量比与非预装的systems.CONCLUSIONIOL有预装的系统的交货更快、更可预言的与一个预装的系统是更小的。而且，一个预装的交货系统相对显示出比非预装的系统推进一只猪的眼睛的更少的OVD。

简介：AIM:ToconductaMeta-analysisforinvestigatingthevariationsinintraocularpressure(IOP)andcentralcornealthickness(CCT)duringnormalpregnancy.METHODS:WesearchedforclinicaltrialspublisheduptoNovember2015withoutlanguageorregionrestrictionsinPubMed,EMBASE,WebofScience,theCochraneCentralRegisterofControlledTrials,Ovid,EBSCO,Elsevier,theChineseBiomedicineDatabase,WanFang,CNKI,CQVIPandGoogleScholar.Studiesoftheocularchangesobservedinpregnantwomenwereselected.ThemainoutcomeswereassessedbychangesinIOPandCCT.RESULTS:Fifteenstudieswereincluded.Insubgroupanalyses,IOPwassignificantlydecreasedduringthesecondMD=-1.53,95%CI(-2.19,-0.87);P<0.00001,andthirdMD=-2.91,95%CI(-3.74,-2.08);P<0.00001trimestersofpregnancy.CCTwasincreasedduringthesecondMD=10.12,95%CI(2.01,18.22);P=0.01,trimesterofpregnancy;moreover,duringthethirdtrimesterofpregnancy,theCCTdisplayedanincreasingtrend,butthedifferencewasnotsignificantMD=5.98,95%CI(-1.11,13.07);P=0.1.CONCLUSION:AdecreaseinIOPisaccompaniedbyanincreaseinCCTinthesecondandthirdtrimestersofanormalpregnancyinwomen.