简介：Triple-negativebreastcancer(TNBC)isdiagnosedmorefrequentlyinyoungerandpremenopausalwomenandishighlyprevalentinAfricanAmericanwomen.TNBCisatermderivedfromtumorsthatarecharacterizedbytheabsenceofER,PgR,andHER2.SopatientswithTNBCdonotbenefitfromhormonalortrastuzumab-basedtherapies.TNBCsarebiologicallyaggressive,althoughsomereportssuggestthattheyrespondtochemotherapybetterthanothertypesofbreastcancer,prognosisremainspoor.Thisisdueto:shorteneddisease-freeintervalintheadjuvantandneoadjuvantsettingandamoreaggressivecourseinthemetastaticsetting.

简介：Inthiswork,negativedielectricnematicliquidcrystalSLC12V620-400,chiraldopantS811,andlaserdyeDCMareusedtopreparedye-dopedchiralnematicliquidcrystallasersample.Inordertoinvestigatetemperature-tunablelasinginnegativedielectricchiralnematicliquidcrystal,wemeasurethetransmissionandlasingspectrumofthissample.Thephotonicbandgap(PBG)isobservedtoredshiftwithitswidthreducingfrom71.2nmto40.2nm,anditsshort-wavelengthbandedgemoves55.3nmwhilethelong-wavelengthbandedgeonlymoves24.9nm.Thewavelengthofoutputlaserisfoundtoredshiftfrom614.4nmat20°Cto662.8nmat67°C,whichisverydifferentfromthepreviousexperimentalphenomena.Therefractiveindices,parallelandperpendiculartothedirectorinchiralnematicliquidcrystalhavedifferentdependenciesontemperature.Theexperimentshowsthatthepitchofthischiralnematicliquidcrystalincreaseswiththeincreaseoftemperature.ThedecreaseinthePBGwidth,differentshiftsofbandedges,andtheredshiftoflaserwavelengtharetheresultsofrefractiveindiceschangeandpitchthermalelongation.

简介：NanoporousanataseTiO2(np-TiO2)electrodeshavebeendevelopedviatheanodizationoftitaniumfoilsinfluoridecontainingelectrolytes,anditsapplicationinrechargeablelithium-ionbatteries(LIBs)wasinvestigated.Fourdifferenttypesofnp-TiO2electrodeswithdifferentporediametersof14.7±8.2nm,12.8±6.8nm,11.0±5.5,and26.7±13.6nmwerefabricatedforevaluatingtheeffectofnanoporouscharacteristicsontheLIBperformance.Thedischargecapacityofthefourbatterytypes1,2,3,and4were132.7mAhg-1,316.7mAhg-1,154.3mAhg-1,and228.4mAhg-1,respectively.Inaddition,theseelectrodes1,2,3,and4exhibitedreversiblecapacityof106.9mAhg-1after295th,180.9mAhg-1after220th,126.1mAhg-1after150th,and206.7mAhg-1after85thcycleatarateof1C,respectively.Itwasnotedthatthecycliclifeofthebatterieshadaninverserelationship,andthecapacityhadaproportionalrelationshiptotheporediameter.Theenhancedelectrochemicalperformanceofthenanoporouselectrodescanbeattributedtotheimprovedconductivityandtheenhancedkineticsoflithiuminsertion/extractionatelectrode/electrolyteinterfacesbecauseofthelargespecificsurfaceareaofnp-TiO2electrodes.

简介：Weinvestigatetheinteractionbetweenapositivemassandanegativeeffectivemassthroughathreemasschainconnectedwithelasticsprings,apairofmassesisdesignedtohaveaneffectivenegativemass,anditinteractswiththethirdpositiveoneasifanequivalenttwo-masschain.Thedynamicsoftheequivalenttwo-masschainshowsthatthetwobodiesmaybeself-acceleratedinsamedirectionwhentheeffectivemassbecomesnegative,theexperimentisalsoconductedtodemonstratethistypeofmotion.Wefurthershowthattheenergyprinciple(Hamilton’sprinciple)isapplicableiftheenergyofthenegativemassunitisproperlycharacterized.Theresultmayberelevanttocompositewithcellsofeffectivenegativemass,theirinteractionwithmatrixmayleadtomorericherunexpectedmacroscopicresponses.

简介：Aninvestigationismadeonthesoilpressureinaninecabinopenedbottomellipticalbarrelstructure.Thecalculationmodelsusingthepenetrationofnegativepressuremethodhavebeendeveloped.Thefirstcalculationmodelisisfortheconstructionstageinvolvingthreezones,namely,passive,transitional,andactiveestablishedforthesoilpressureincabins.Theothercalculationmodelisbasedontheusestage,withthetwo(passiveandactive)zonesforthesoilpressureincabins.Theheightofzonesandthetheoreticalanalyticalsolutionsofinnersoilpressurearederived.Theanalyticalformulasofthemodelsareprovedusingthefiniteelementmethodandexperimentaldata,andtheformulasareanalyzedintheinnersoilpressureinthesamecondition.Thecalculationmodelscanbeusedforothermulti-positionstructuraldesignorconstruction.