简介：Thecapabilityandreliabilityarecrucialcharacteristicsofmobilerobotswhilenavigatingincomplexenvironments.Theserobotsareexpectedtoperformmanyusefultaskswhichcanimprovethequalityoflifegreatly.Robotlocalizationanddecisionmakingarethemostimportantcognitiveprocessesduringnavigation.However,mostofthesealgorithmsarenotefficientandarechallengingtaskswhilerobotsnavigatethroughcomplexenvironments.Inthispaper,weproposeabiologicallyinspiredmethodforrobotdecision-making,basedonrat’sbrainsignals.Rodentsaccuratelyandrapidlynavigateincomplexspacesbylocalizingthemselvesinreferencetothesurroundingenvironmentallandmarks.Firstly,weanalyzedtherats’strategieswhilenavigatinginthecomplexY-maze,recordedlocalfieldpotentials(LFPs),simultaneously.TherecordedLFPswereprocessedanddifferentfeatureswereextractedwhichwereusedastheinputintheartificialneuralnetwork(ANN)topredicttherat’sdecision-makingineachjunction.TheANNperformancewastestedinarealrobotandgoodperformanceisachieved.Theimplementationofourmethodonarealrobot,demonstratesitsabilitiestoimitatetherat’sdecision-makingandintegratetheinternalstateswithexternalsensors,inordertoperformreliablenavigationincomplexmaze.

简介：由于存在止痛剂的低效率和副作用，长期的疼痛在诊所成为了最复杂、困难的问题之一。Monoacylglycerol脂肪分解酵素(MAGL)是在endocannabinoid系统的必要hydrolase并且为疼痛的治疗作为一个潜在的目标被识别了。在现在的学习，我们设计了并且综合12tanshinoneIIA类似物并且对MAGL屏蔽了他们的活动。选择混合物在vivo为止痛活动被测试，与扭曲测试模型的醋酸。在测试混合物之中，加重III-3(IC50120nmol

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简介：PolysaccharideextractedfromEnteromorphaproliferapossessedexcellentbiologicalactivities,butitsmolecularweightwasgreatlyhighwhichinfluencedtheactivity.OrganicSehadhigherbiologicalactivitiesandwassaferthaninorganicSespecies.Inthepresentstudy,Enteromorphapolysaccharidewasdegradedtolowmolecularweightbyfree-radicaldegradationmethodofH2O2andascorbicacid.Bysinglefactorandorthogonalexperiments,theoptimaldegradationconditionswerereactiontimeof2h,reactiontemperatureof50℃,H2O2/ascorbicacid(n/n=1:1)concentrationof15mmolL-1,andsolid-liquidratioof1:50(gmL-1).Then,thedegradedpolysaccharidewaschemicallymodifiedtoobtainitsselenidederivativesbynitricacid-sodiumselenitemethod.Theseleniumcontentwas1137.29μgg?1,whilethecontentofsulfateradicalhadnochange.IRspectraindicatedthattheseleniteestergroupwasformed.Degradedpolysaccharideselenidewascharacterizedandevaluatedforantioxidant,antifungalandantibacterialactivities.TheresultsshowedthatdegradedpolysaccharideselenidehadstrongcapacityofscavengingDPPHand·OHfreeradical.IthadsignificantantibacterialpropertiesforEscherichiacoli,BacillussubtilisandSalmonellaspp.,anditalsohadsignificantantifungalpropertiesforAppleanthrax.Theresultascertaineddegradationandselenylationmodificationdidnotchangethemainstructureofpolysaccharides.Itwaspossiblethatfree-radicaldegradationwasaneffectivewayforenhancingantioxidantactivitytodecreasemolecularweightofpolysaccharides.

简介：GreenhousehorticulturalproductioncurrentlyrepresentsanimportantandgrowdngsectorofCanada'sfoodandplantproducproductionsystems.Since2006,thevalueofgreenhousevegetablecropsinCanadaexceedsthatoffieldgrowncrops,signalinganimportantshiftinthew-ayfoodiscultivatedinthecountry.Whilemanyfactorshavecontributedtothischange,amajorareaofinnovationincludesthediscoveriesandadvancesmadeinthedevelopmentofcommercialgreenhouseproductionsystemsaswellastheintegrationofbiologicalcontrolstrategiesforsustainablepestmanagement.Withthisfocus,thisreviewoffersabriefoverviewoftheCanadiangreenhouseindustry,includingadescriptivelistofcommonlyusedbiologicalcontrolorganisms,aswellastheroleCanadianresearchhasplayedinthedevelopmentoftheseagents.WealsoaddressthethreatsthatCanadiangreenhouseproducersfacebyinvasivepestsandthecomplicationsthesehavecreatedforthecommercializationofnovelbiologicalcontrolagents.Thisinformationmayserveasaguideforthedevelopmentofparalleltechnologiesandtoolsinotherpartsoftheworldwheregreenhouseproductionisexpanding.

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