简介:为米饭核心收集的十一评估参数被估计基于ongenotypic价值和分子的标记信息。与混合线性模型相结合的蒙特卡罗模拟被用来从环境消除干扰以便拉更可靠的结果。范围(CR)的巧合率是最佳的参数。吝啬的Simpson索引(M_D),基因差异(M_I)的吝啬的Shannon编织索引和吝啬的多型性信息内容(M_(照片))是重要的评估参数。变异系数(VR)的可变的率能为评估核心收集的变化度充当一个重要引用参数。多态的loci(p)的百分比能为核心收集的尺寸被用作一个决心参数。吝啬的差别百分比(MD)是为核心收集的可靠性判断的一个决心参数。为在研究选择的核心收集的有效评估参数能在不同plantgermplasm人口为采样百分比被用作标准。
简介:Weproposeanddemonstrateataperedhollowannularcorefiber(HACF)couplerforexcitationofwhisperinggallerymodes(WGMs)ofanembeddedmicrosphereresonator.ThecouplerissimplyfabricatedbyfusionsplicingofasegmentofHACFwiththesingle-modefiber(SMF),andthenimprovedbytaperingthesplicingjointtoreducethecone-apexangle.Therefore,thecouplingefficiencyfromtheSMFtotheHACFisenhancedtoexcitevariousWGMsviaevanescentfieldcoupling.Normalpositive,negativesymmetricalLorentzianandasymmetricFanolineshapescanbeobtainedbyvaryingtheresonatorsizeandlocation.AnotherinterestingphenomenonisobservedthatahigherQ-factormodeinalowerQ-factormodehasacontrastashighas58.Temperaturesensingwithgoodstabilityisalsodemonstrated.ThisembeddedWGMmicrosphereresonatorinthetaperedHACFisexpectedtopromoteenvironmentaladaptabilityinpracticalapplicationsduetoitssimplicityandrobustness.
简介:ThereisabeltofmetamorphiccorecomplexesinthewesternmarginoftheYangtzecraton.ThegeologicalsettingofthebeltissimilartothatoftheCordilleranmetamorphiccorecomplexes.AtypicaloneinthisbeltistheJianglangmetamorphiccorecomplex,whichhasaconfigurationconsistingofthreelayers:acorecomplexconsistingofMesoproterozoicschistsequence,aductilemiddleslabconsistingofPaleozoicmeta-sedimentary-basaltcharacterizedbythedevelopmentof"foldinglayer"andanuppercoverconsistingofXikangGroupwhichhassufferedbothbucklingandflattening.AdetachmentfaultdevelopedalongthecontactboundarybetweenthecoverandbasementcausestheomissionofUpperSinianandCambrianatthebaseofcover.Alotofnormalductileshearzonesdevelopedinthecovercausesthethinningofit.Allthefeaturesshowthattheearlyextensionresultsinthethinningofcrust,buttheformationofthedomeandexposureofbasementrocksmaybetheresultsofsuperimp
简介:A3D非静水力学的模型葡萄(全球/地区性的吸收和预言系统)的动态核心在Yin-Yang格子上被开发处理极的问题并且提高计算效率。强迫的三维的Coriolis被介绍给新核心,并且强迫的Coriolis的完整的表示使分享在殷和杨子域之间的代码直接。类似于在葡萄建模的原版,一个半含蓄的semi-Lagrangian计划与跨边界的运输的另外的安排为时间的集成和移流被采用。在时间的非集中的秒顺序和空间discretization下面,干燥nonhydrostatic框架作为一个椭圆的问题的答案被总结。产生Helmholtz方程被解决与概括与经典Schwarz方法在合作结合剩余解答者。尽管方程的系数与在原来的模型的那些相当不同,新核心的计算过程只是一样。双性人立方的Lagrangian插值服务向Dirichlet类型边界条件提供在子域之间的数据转移。干燥核心与几个基准测试用例被评估,并且所有测试显示合理数字稳定性和计算性能。平衡流动的坚持和导致山脉的Rossby波浪和Rossby-Haurwitz波浪的开发在半含蓄的semi-Lagrangian证实3DCoriolis条款的适当安装Yin-Yang格子上的动态核心。
简介:Inthispaper,wepresentamode-selectivecouplerbasedonadual-coreall-solidphotonicbandgapfiber(AS-PBGF).Becausetheyareall-solid,AS-PBGF-basedmodeconvertersareeasiertosplicetootherfibersthanthosebasedonair-holephotoniccrystalfibers.ModeconversionsbetweentheLP01andLP11modes,LP01andLP21modes,andLP01andLP02modesareobtainedatthewavelengthλ=1550nm.The3dBwavelengthbandwidthofthesemodeconvertersare47.8,20.3,and20.3nm,respectively.
简介:AbstractAfrican swine fever virus (ASFV) is the causative agent of African swine fever, a highly fatal hemorrhagic disease of pigs, which has resulted in great economic losses to the global pork industry, especially in Asia. ASFV particles are comprised of multiple layers encompassing the genomic DNA. Though the capsid structure has been determined, very little is known about the structure of the core shell. The precursor polyprotein pp62 is the structural component of the core shell that gives rise to the p35 and p15 proteins. Herein, we describe the crystal structure of p15 at a resolution of 2.2 Å. The structure of p15 exhibits as a trimeric conformation that is mainly mediated by intermolecular disulfide bonds and supported by multiple hydrogen bond interactions. The button conformation on the surface of adjacent molecules may also play a role in trimeric formation of the ASFV p15. The center of the p15 trimer exhibits opposite electrostatic characteristics on each side. These findings benefit our understanding of ASFV core shell assembly and will aid in the design of antiviral drugs and vaccines.
简介:Thisstudyaimedtoexploreuniversitystudents'perceptionsontheimportanceofcorecompetenciesforthe21stcentury.Acrosssectionalsurveyresearchusingaself-reportquestionnaireinvolving48Likert-typeitemswasusedtocollectdatafrom869universitystudentsinChinawhovoluntarilyparticipated.MultidimensionalanalysiswithRaschratingscalemodelfoundthedatafittedtheRaschmodelwell.TheresultsshowedthatChineseuniversitystudentsplacedstrongimportanceonthemajorityofcompetencieslistedinthemodifiedquestionnaireof21stCenturyCoreCompetenciesforHigherEducation,especiallyincompetencegroupsofInterpersonalCommunicationandCharacterandCivicLiteracybutlesssointhoseofCreativityandProblemSolvingandGlobalandInternationalPerspective.
简介:TheequationofmotionofsandwichbeamwithpyramidallatticecoreinthesupersonicflowconsideringgeometricnonlinearityisformulatedusingHamilton’sprinciple.Thepistontheoryisusedtoevaluateaerodynamicpressure.Thestructuralaeroelasticpropertiesareanalyzedusingfrequency-andtime-domainmethods,andsomeinterestingphenomenaareobserved.Itisnotedthattheflutterofsandwichbeamoccursunderthecouplingeffectoflowordermodes.Thecriticalflutteraerodynamicpressureofthesandwichbeamishigherthanthatoftheisotropicbeamwiththesameweight,lengthandwidth.Theinfluenceofinclinationangleofcoretrussonfluttercharacteristicisanalyzed.
简介:Glioblastoma(GBM)isoneofthemostlethalhumancancers.GenomicanalysesdefinethemoleculararchitectureofGBMandhighlightacentralfunctionformechanistictargetofrapamycin(mTOR)signaling.mTORkinaseexistsintwomultiproteincomplexes,namely,mTORC1andmTORC2.Thesecomplexesdifferintermsoffunction,regulationandrapamycinsensitivity.mTORC1iswellestablishedasacancerdrugtarget,whereasthefunctionsofmTORC2incancer,includingGBM,remainspoorlyunderstood.ThisstudyreviewstherecentfindingsthatdemonstrateacentralfunctionofmTORC2inregulatingtumorgrowth,metabolicreprogramming,andtargetedtherapyresistanceinGBM,whichmakesmTORC2asacriticalGBMdrugtarget.
简介:ThemagneticfusionreactorusingtheadvancedD-3Hefuelshastheadvantageofmuchless-neutronproductionssothattheconsequentdamagestothefirstwallarelessserious.Iftheestablishmentofthiskindofreactorbecomesrealistic,theexplorationof3Heonthemoonwillbelargelymotivated.Basedonrecentprogressesinthesphericaltorus(ST)research,wehavephysicallydesignedaD-3HefusionreactorusingtheextrapolatedresultsfromtheSTexperimentsandalsothepresent-daytokamakscaling.Itisfoundthatthereactorsizesignificantlydependsonthewallreflectioncoefficientofthesynchrotronradiationandoftheimpuritycontaminations.ThesecondaryreactionbetweenD-DthatpromptlyleadstotheD-Treactionproducing14MeVneutronsisalsoestimated.ComparisonofthisD-3HeSTreactorwiththeD-Treactorismade.
简介:克莱在在抵抗力索引之间的关系上有重要影响我和水浸透Sw(即,I-Sw关系)水库岩石因为它复杂化这些岩石的当前的路径。因为在岩石内的泥土的毛孔结构,微分发和内容不能在实验期间被观察并且控制,由物理实验室大小在各种各样的岩石的传导性上揭示这些泥土效果的物理机制是困难的。我们在场在水库的电的运输性质上学习这些泥土效果的一条数字岩石途径用格子气体在毛孔规模摇自动化(LGA)方法。数字岩石样品从水库岩石的SEM图象与谷物尺寸分发的信息被构造。LGA然后充分在这些数字岩石上被使用与液体浸透了为在I-Sw关系的非高射炮行为上揭示体积的效果和泥土的分发模式模仿电的运输性质。在模仿的结果和实验室大小之间的好协议清楚地在岩石物理的数字研究表明LGA的有效性。把研究基于这些,一个新模型为描述在浸透代表和泥土的体积之间的关系的份量上被开发了(V嘘)。这开发可以在水库岩石中为液体浸透改进评估。
简介:Au-core/Pt-shellnanorods(Au@PtNR)被一个Au调停nanorod的生长方法准备了,并且他们在联合条件下面展出高电磁的地改进。由Au核心产生的高电磁的领域的远程的效果增加了,电磁的领域改进能被改变nanostructures的形态学控制。在这研究,我们用有限差别时间域(FDTD)在电磁的领域改进的模拟上报导结果方法,考虑Au@PtNR的真实形状。由于热点效果,电磁的领域能在磅nanodots之间是局部性的。电磁的领域改进被发现相当独立于磅内容,而本地粗糙和小锋利的特征力量显著地修改近地。当电磁的领域改进能被磅nanodots的分发在Au核心上调节,Au@PtNR能在相关区域发现潜在的应用。