简介:Core-shellstructurednanosphereswithmesoporoussilicashellandNicore(denotedasNi@meso-SiO2)arepreparedthroughathree-stepprocess.MonodispersedNiprecursorsarefirstprepared,andthencoatedwithmesoporousSiO2.FinalNi@meso-SiO2spheresareobtainedaftercalcination.TheproductsarecharacterizedbyX-raypowderdiffraction,transmissionelectronmicroscopyandN2adsorption-desorptionmethods.Thesesphereshaveahighsurfaceareaandarewelldispersedinwater,showingahighcatalyticactivitywithaTOFvalueof18.5,andoutstandingstabilityinhydrolyticdehydrogenationofammoniaboraneatroomtemperature.
简介:Thedispersioncompensationpropertiesofdual-concentriccorephotoniccrystalfibersaretheoreticallyinvestigatedinthisletter.Theeffectsofgeometricstructureonthedispersionpropertiesofdual-concentriccorephotoniccrystalfibersarecarefullystudiedbyfiniteelementmethod.Thefirstlayerofholesaroundthecoreareaisenlargedinanewmannerwiththenear-corepointfixed.Consideringthetradeoffamongseveralparameters,resultsshowthatthedispersioncompensationwavelengthandstrengthcanbetunedtodesiredvaluesbyconstructinganappropriatedesignofthegeometricstructureofphotoniccrystalfibers.
简介:Anexperimentaladvancedsuperconductingtokamak(EAST)operationwindowwiththelowerhybridcurrentdrive(LHCD)inH-modeisestimatedbyusingacore-SOL-divertor(C-S-D)modelvalidatedbythepresentEASTdivertorexperiments.Theoperationwindowconsistsoffourlimitsincludingtwousuallimits,oneofwhichisthemaximumallowableheatloadontothedivertorplate,andtwoadditionallimitsassociatedwiththeLHCD.ThepredictiveEASToperationwindowisnotqualifiedtofulfillitsmissionforhighinputpower.Toextendtheoperationwindow,gaspuffingandimpurityseedingarepresentedastwoeffectivemethods.Inaddition,theeffectoftheLHCDcurrentontheoperationwindowisalsodiscussed.OurnumericalanalysisresultsprovideareferenceforthesafeoperationofEASTexperimentswithLHCDinfuture.
简介:Glioblastoma(GBM)isoneofthemostlethalhumancancers.GenomicanalysesdefinethemoleculararchitectureofGBMandhighlightacentralfunctionformechanistictargetofrapamycin(mTOR)signaling.mTORkinaseexistsintwomultiproteincomplexes,namely,mTORC1andmTORC2.Thesecomplexesdifferintermsoffunction,regulationandrapamycinsensitivity.mTORC1iswellestablishedasacancerdrugtarget,whereasthefunctionsofmTORC2incancer,includingGBM,remainspoorlyunderstood.ThisstudyreviewstherecentfindingsthatdemonstrateacentralfunctionofmTORC2inregulatingtumorgrowth,metabolicreprogramming,andtargetedtherapyresistanceinGBM,whichmakesmTORC2asacriticalGBMdrugtarget.
简介:Lithium-sulfur(Li-S)batteriesbelongtooneofthepromisingtechnologiesforhigh-energy-densityrechargeablebatteries.However,sulfurcathodessufferfrominherentproblemsofitspoorelectronicconductivityandtheshuttlingofhighlydissolublelithiumpolysulfidesgeneratedduringthecycles.Loadingsulfurintoporouscarbonshasbeenprovedtobeaneffectiveapproachtoalleviatetheseissues.Mesoporousandmicroporouscarbonshavebeenwidelyusedforsulfuraccommodation,butmesoporouscarbonshavepoorsulfurconfinement,whereasmicroporouscarbonsareimpededbylowsulfurloadingrates.Here,acore-shellcarbon,combiningboththemeritsofmesoporouscarbonwithlargeporevolumeandmicroporouscarbonwitheffectivesulfurconfinement,waspreparedbycoatingthemesoporousCMK-3withamicroporouscarbon(MPC)shellandservedasthecarbonhost(CMK-3@MPC)toaccommodatesulfur.Aftersulfurinfusion,theas-obtainedS/(CMK-3@MPC)cathodedeliveredahighinitialcapacityofupto1422mAh·g-1andsustained654mAh·g-1reversiblespecificcapacityafter36cyclesat0.1C.Thegoodperformanceisascribedtotheuniquecore-shellstructureoftheCMK-3@MPCmatrix,inwhichsulfurcanbeeffectivelyconfinedwithinthemeso/microporouscarbonhost,thusachievingsimultaneouslyhighelectrochemicalutilization.