简介:Prostatecancergene3(PCA3,alsoknownasDD3)isanewbiomarkerthatcouldimprovetheaccuracyofprostatecancerdiagnosis.Itisagreatbiomarkerwithfairlyhighspecificityandsensitivity.Theincidenceofprostatecancerisrisingsteadilyinmostcountries.Thecommonlyusedprostate-specificantigen(PSA)testoncegavepeoplehopeforearlydiagnosisofprostatecancer.However,thelowspecificityofthePSAtesthasresultedinalargenumberofunnecessarybiopsiesandovertreatment.Duringthepastdecade,manynewprostatecancerbiomarkershavebeenfound.Amongthese,PCA3isthemostpromising.Duetoitsgreatperformanceindistinguishingprostatecancerfromotherprostateconditions,PCA3couldlikelybeappliedforearlydiagnosisofprostatecancer,patientfollow-up,prognosisprediction,andtargetedtherapy.Afteryearsofresearch,wehaveobtainedsomeknowledgeaboutthesequenceofPCA3gene.WehavealsodeterminedtherelationshipbetweenPCA3andtheproliferationofprostatecancercellsandlearnedsomeinformationabouthowPCA3affectstumor-relatedgenesandproteins.APCA3scorehasbeencreated,andithasbeenusedinavarietyofstudies.SomeresearchershaveevenappliedPCA3totargetedtherapyandobtainedagoodeffectinvitro.Thisreviewdescribesthecurrentstateofresearch,andexploresthefutureprospectsforPCA3.更多还原
简介:Transversemodecharacteristicsofalaserarerelatedtoavarietyofinterestingapplications.Anon-demandmodesolidlaserinthe1064nmbandwasproposedpreviously.Inthispaper,weprovideafiberlaserforon-demandmodesinthe1550nmbandtoprescribethepureandhigh-qualityemissionofahigher-ordertransverselasermode,basedonasimpleconstructionwithonespatiallightmodulator(SLM)andasingle-modeerbium-dopedfiber(SM-EDF).TheSLMisdesignatedtogeneratethedesiredhigher-ordermodeandseparatethehigher-ordermodeandthefundamentalmode.Thefundamentalmodeoscillatesinthefiberringlaser,andthereforetheSM-EDFcanbepumpedwithasingle-mode980nmlaser,nomatterwhathigher-ordermodeisprescribed.Inthisproof-of-principleexperiment,high-qualityhigher-ordermodesareobservedfromLP01toLP105.Stableemissionandreal-timeswitchingbetweenmodescanbeeasilyrealizedbyalteringthephaseontheSLM.Inaddition,thepropagationoftheLP01,LP11,LP21,andLP02modesfromthefiberlaserisalsodemonstratedinafour-modefew-modefiber.
简介:我们构造稀少的表示和subspace表示的一个合作模型。首先,我们代表追踪在原则部件分析(PCA)指向subspace,然后我们采用L1规则化限制剩余学期的稀少,限制表示系数的稀少的一个L2规则化学期,并且限制在重建和目标之间的距离的一个L2标准。然后,我们在粒子过滤器框架实现算法。而且,一个反复的方法被介绍得到剩余和系数的全球最小。最后,一个其他的模板更改计划被采用避免被不精密的更改引起的追踪的飘移。在实验,我们在9个序列上测试算法,并且把结果与5个state-of-art方法作比较。根据结果,我们能断定我们的算法比另外的方法更柔韧。
简介:WiththevigorousdevelopmentofequipmentmanufacturingindustryinChina,higherrequirementstotheequipmentsupportabilityareputforward.Howtoevaluatethesupportabilityofequipments(especiallytheaviationequipment-aircraft)objectivelyandcorrectlyistheproblemtobesolvedinthedevelopmentofaviationequipmentsconstruction,demonstrationandbattleapplication.Aimedattheneedsofthesupportabilityanalysisofcomplexequipmentsystems-aircraft,amodelofaircraftsupportconceptevaluationbasedonDEA(dataenvelopmentanalysis)andPCA(principalcomponentanalysis)isproposed.Themodelisusedtoevaluateacertainaircraftsupportconcept.Theprocessandtheresultsofevaluationshowthatproposedmodelisfeasibleandeffective.Themodelissuitableforadvancedaircraftsupportconceptevaluation.Thefeasibilityandeffectivenessoftheproposedmodelisverifiedbytheanalysisoftheevaluationresults.Thismethodisapplicabletotheevaluationofaircraftsupportconcepts.
简介:针对我国企业信用评价问题的特点,文章分析了企业信用评价基本原则和主要影响因素,建立了企业信用评价指标体系。企业信用评价是一类包括一系列独立变量的分类问题,将主成分分析与模糊理论引入信用评价中,构建基于PCA/FCM的企业信用评价模型,这使得模型更接近人们的思维方式、指标赋权更为客观。应用该模型及SPSS11.0、MATLAB7.0对所选企业研究显示:该模型非常有效和实用。
简介:测量了Er3+:YVO4晶体的吸收谱,得到Er3+离子在YVO4晶体中的光辐射特性。通过Dexter理论计算得到了4I13/2+4I13/2→4I9/2+4I15/2和4I11/2+4I11/2→4F7/2+4I15/2的交叉弛豫几率分别为P1=6.718×105s-1和P2=1.676×105s-1,同时建立了描述Er3+离子跃迁的动力学模型,利用速率方程讨论了P1、P2对1550nm荧光的影响。
简介:【摘要】目的:探讨采用1550nm非剥脱点阵激光的方法治疗痘坑痘印的临床效果。方法:纳入于我院就诊的50例痘坑患者,在我院治疗时间为2022.02~2023.02,均采用1550nm非剥脱点阵激光进行治疗,并对治疗结果进行观察。结果:对于带有黑褐色色素沉着的痘坑,总有效率为53.85%;而对于单纯的凹陷性痘坑,其总有效率仅为25.00%。表明带有黑褐色色素沉着的痘坑在治疗后的效果明显优于单纯的凹陷性痘坑(P<0.05)。接受治疗后,患者未出现任何色斑沉着、水疱形成等不良反应,可能存在短暂红肿、疼痛和灼热感等症状,但这些症状通常会在1-3 d内自行消失。在红肿消退后,会出现像针孔一样的黑褐色细小薄痂,大约需要5-7 d才会长出新的皮肤。结论:对痘坑(带有黑褐色色素沉着痘坑、单纯凹洞性痘坑)患者,采用1550 nm非剥脱点阵激光治疗效果较好,减轻不良反应,应推广借鉴。