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简介:Itisnotunusualforthelevelofamonthlyeconomictimeseries,suchasindustrialproduction,retailandwholesalesales,monetaryaggregates,telephonecallsorroadaccidents,tobeinfluencedbycalendareffects.Sucheffectsarisewhenchangesoccurinthelevelofactivityresultingfromdifferencesinthecompositionofcalendarbetweenyears.Thetwomainsourcesofcalendareffectsaretradingdayvariationsandmovingfestivals.Ignoringsuchcalendareffectswillleadtosubstantialdistortionsintheidentificationstageoftimeseriesmodeling.Therefore,itismandatorytointroducecalendareffects,whentheyarepresentinatimeseries,asthecomponentofthemodelwhichonewantstoestimate.
简介:Azathioprine当前是在煽动性的肠疾病的维护治疗的关键药。然而,仍然有要决定的一些实际问题:一个人是我们多长必须维持这药。给疾病是标明日期长期的、非可医好的条件的那煽动性的肠,治疗应该是不定的,仅仅功效的损失或严肃的副作用的外观可以引起退却。关于到功效和他们的维护随着时间的过去,证据从长远的观点看支持这药的连续实用性:事实上,它的退却很实质地增加恶化的风险。关于副作用,azathioprine是一很好相对容忍了药和甚至不定的使用似乎安全。延长使用的主要理论风险将是癌症的骨髓中毒性,hepatotoxicity,和发展。事实上,严肃的骨髓抑制或严肃的肝损坏是不平常的,并且能与这药的合适的使用被最小化。最近的遇见的分析建议淋巴瘤的风险是真实的,但是单个风险是相当低的,并且决定分析从长远的观点看建议有利利益/风险比率。在有azathioprine谁有效、很好容忍的煽动性的肠疾病的病人,因此,这药不应该被停止。这个建议作为单个维护药使azathioprine的使用担心,并且对收到伴随物生物制品疗法的病人未必适用。
简介:Inthispaper,weproposeasusceptible-infected-susceptible(SIS)modeloncomplexnetworks,small-world(WS)networksandscale-free(SF)networks,tostudytheepidemicspreadingbehaviorwithtimedelaywhichisaddedintotheinfectedphase.Consideringtheuniformdelay,thebasicreproductionnumberR_0onWSnetworksandR_0onSFnetworksareobtainedrespectively.OnWSnetworks,ifR_0≤1,thereisadisease-freeequilibriumanditislocallyasymptoticallystable;ifR_0>1,thereisanepidemicequilibriumanditislocallyasymptoticallystable.OnSFnetworks,ifR_0≤1,thereisadisease-freeequilibrium;ifR_0>1,thereisanepidemicequilibrium.Finally,wecarryoutsimulationstoverifytheconclusionsandanalyzetheeffectofthetimedelayr,theeffectiverateλ,averageconnectivityandtheminimumconnectivitymontheepidemicspreading.
简介:Inordertosolvetheproblemofearlyestimationofmoderatelystrongaftershockdurationtimeinanearthquakesequence,thisstudyhasbeenconducted.First,thedefinitionofthestrongaftershockhasbeengiven.Itispointedoutthatthereisadifferenceinthestrongaftershockdurationtimebetweenthemainshocktypesequenceandthestrongearthquakeswarmsequence.Afterdividingthethreecases,i.e.,astrongaftershockdurationtimelargerthan1day,smallerthan1day,andnostrongaftershockoccurredinamainshocktypesequencebyusingthepatternrecognitionmethod,wegavetheroughcorrelationrelationbetweenstrongaftershockdurationtimeandfirstlargeshockmagnitudefortwotypesofsequences.Finally,thejudgmentindexandmethodofestimatingstrongaftershockdurationtimesfordifferentsequencetypeshavebeengiven.
简介:TheconstructionoftheGeologicTimeScale(GTS)isatitanicscientificchallengethathasbeenunderwayfortwocenturiesandwillrequiremuchdedicatedeffortinthefuture.ItalypreservesaparamountstratigraphicrecordofMesozoicandCenozoicmarinesedimentsthathavebeensignificantinthedevelopmentofthemodernGTS.TheItalianstratigraphicrecordhasbeenhistori-callyimportantinintroducinganddefiningthestandardChronostratigraphicUnits(CUs)oftheNeogeneandQuaternary.PelagicsuccessionsfromNorthernApen-ninesandSouthernAlpshavebeenusedintheseventiesforintegratingthelateCretaceous-PaleogeneGeomag-neticPolarityTimeScale(GPTS)withplanktonicmicrofossilbiostratieraohvandstandardCUs.Thiswasamajorcontributiontotheconstructionofanewgener-ationofGTSbasedonintegratedmagnetobiochronol-ogy.ThemiddleMiocenetoearlyPleistocenemarinerecordfromSicilyandsouthernItalyhasbeenfunda-mentalforestablishingtherecentlydevelopedAstro-nomicalTimeScale(ATS).Inprospect,therearemanypotentialsstilltobeexploitedintheItalianmarinestratigraphicrecordforimplementingtheGTSbydefin-ingGSSPsofvariousCUs,improvingmagneto-biochronologyandextendingdownwardstheATS.
简介:Usingthetimereversal(TR)-reversetimemigration(RTM)mixedmethod,thenumericalanalysistowardstheacousticfieldfordetectionandlocationoftargetsinlayeredmediaisperformed.Firsttheapproachesandstepsofthenumericalanalysisandsimulationforacousticfieldareproposed,then,theacousticfielddistributionofsingletargetandmultipletargetsarefurthercomputedbyusingtheapproachesofsingleemission-multiplereceivingandmultipleemission-multiplereceiving.Thenumericalsimulationresultsindicatethattargetdetectionandlocationcanbewellrealized.Bycomparison,goodresultsareobtainedfromthebothtwoapproaches,butlargetime-consumingisobservedinwayofmultipleemission-multiplereceiving,andsowouldbeunacceptable.Additionally,theimprovedwayisalsoproposedformultipletargetdetection.
简介:Thispaperpresentsacopulatechniquetodeveloptime-variantseismicfragilitycurvesforcorrodedbridgesatthesystemlevelandconsiderstherealistictime-varyingdependenceamongcomponentseismicdemands.Basedonmaterialdeteriorationmechanismsandincrementaldynamicanalysis,thetime-evolvingseismicdemandsofcomponentswereobtainedintheformofmarginalprobabilitydistributions.Thetime-varyingdependencesamongbridgecomponentswerethencapturedwiththebestfittingcopulafunction,whichwasselectedfromthecommonlyusedcopulaclassesbytheempiricaldistributionbasedanalysismethod.Thesystemtime-variantfragilitycurvesatdifferentdamagestatesweredevelopedandtheeffectsoftime-varyingdependencesamongcomponentsonthebridgesystemfragilitywereinvestigated.Theresultsindicatethetime-varyingdependenceamongcomponentssignificantlyaffectsthetime-variantfragilityofthebridgesystem.Thecopulatechniquecapturesthenonlineardependenceamongcomponentseismicdemandsaccuratelyandeasilybyseparatingthemarginaldistributionsandthedependenceamongthem.
简介:摘要目的探讨产道血肿形成的原因和处理方法。结果主要症状为会阴部疼痛、坠胀,见于阴道两侧沟、会阴侧切处及其深部。多见于初产妇。以产后4小时特别是产后2小时即可发现并有明显症状。结论为预防产道血肿的形成,要加强产后观察,认真细致地进行阴道缝合。