简介:Anexperimentofuniaxialcompressionwascarriedoutonsamplesof8representativerocktypes.Thetemporalvariationsoftheremanentmagnetization,strainandacousticemissionofsampleswererecordedandinvestigated,especiallywhenthesampleswereunderconstantloadandwhentheyhadjustbeenunloaded.Itwasfoundthatmostsamplesstillshowedchangesoftheirremanentmagnetizationunderconstantloadandthetendencyofthesechangesremainedthesameasthatbeforetheloadhadbeenkeptconstant.Inthemeantime,similarchangesofstrainswereobservedaswell.However,inashorttimeperiodimmediatelyafterthesamplehadbeencompletelyunloaded,thevariationsofremanentmagnetizationandstrainswerestillobserved.Theabovephenomenaseemtobethereflectionofrheologicalpropertiesofrocks.Itisinterestingtonotethatsomesimilarphenomenawerealsofoundinfieldobservations,suchasaseismicgeomagneticchangesandsecularvariationinlocalgeomagneticfieldbeforeandaftere
简介:【摘要】目的:观察表没食子儿茶素没食子酸酯 (EGCG)对 D-半乳糖诱导的阿尔茨海默病( AD)模型大鼠 Rho/Rho相关卷曲螺旋形成蛋白激酶( ROCK)通路的影响。 方法:对照组给予常规饲料及蒸馏水喂养,模型组给大鼠 150mg/kg*d皮下注射 D-半乳糖,连续 42天,制备 AD大鼠模型。造模 14天后,第二组给予生理盐水灌胃,第三组给予 0.04%EGCG2mg/kg*d灌胃,连续 28天,前后分别采用 Morris水迷宫检验大鼠的行为变化,制作 HE染色切片,免疫组化检测 β 淀粉样蛋白和 ROCK的表达。 结果: Morris水迷宫测试中,模型组大鼠的平均逃避潜伏期显著高于 EGCG组和西药组。 对照组、 EGCG组和西药组大鼠的 β 淀粉样蛋白显著低于模型组大鼠( P < 0.05); 对照组、 EGCG组和西药组大鼠的 ROCK蛋白的表达显著高 于模型组大鼠。 模型组大鼠的 SOD、 GSH-Px水平显著低于 EGCG组和 西药组( P < 0.05)。 结论: EGCG可能通过抑制 β 淀粉蛋白和激活 ROCK的表达水平,增加 SOD、 GSH-Px表达来改善其认知障碍。
简介:Faultisacomplexdynamicsystemcontrolledbythecouplingofrocktexture,reaction,fluidflow,stress,androckdeformationmechanism.Acoupledreaction-transport-mechanicaldynamicmodelforfaultsystemisestablishedanddescribedinthispaper.AnexampleispresentedfortheShuikoushandeposit,Hunan.Theresultsofdynamicsimulationindicatethattheevolutionandmagnitudeoffracturepermeabilityofdifferentrocksaredifferent,andthatfaultingcanenhancethespatialheterogeneityofrockpermeabilityandfacilitatefluidflowandmineralizationinlocalfaultzone.Thepressureforafaultusuallyshowsavariationmodeofaperiodicoscillationwithtime,whichreflectsthechaoticbehavioroftheevolutionofafault.
简介:StabilizedorChebyshevexplicitmethodshavebeenwidelyusedinthepasttosolvestiffordinarydifferentialequations.MakinguseofspecialpropertiesofChebyshev-likepolynomials,thesemethodshavefavorablestabilitypropertiescomparedtostandardexplicitmethodswhileremainingexplicit.Anewclassofsuchmethods,calledROCK,introducedin[Numer.Math.,90,1-18,2001]hasrecentlybeenextendedtostiffstochasticdifferentialequationsunderthenameS-ROCK[C.R.Acad.Sci.Paris,345(10),2007andCommun.Math.Sci,6(4),2008].InthispaperwediscusstheextensionoftheS-ROCKmethodstosystemswithdiscretenoiseandproposeanewclassofmethodsforsuchproblems,theT-ROCKmethods.Onemotivationforsuchmethodsisthesimulationofmulti-scaleorstiffchemicalkineticsystemsandsuchsystemsarethefocusofthispaper,butournewmethodscouldpotentiallybeinterestingforotherstiffsystemswithdiscretenoise.TwoversionsoftheT-ROCKmethodsarediscussedandtheirstabilitybehaviorisanalyzedonatestproblem.ComparedtotheT-leapingmethod,asignificantspeed-upcanbeachievedforsomestiffkineticsystems.Thebehavioroftheproposedmethodsaretestedonseveralnumericalexperiments.
简介:Geothermalenergyisapreciousresource,whichiswidelydistributed,varied,andabundant.Chinahasenteredaperiodofrapiddevelopmentofgeothermalenergysince2010.Asshallowgeothermalenergypromoting,thedepthofhydrothermalgeothermalexplorationisincreasing.ThequalityofHotDryRock(HDR)andrelatedexploratorytechnologiesarebetterdevelopedandutilized.Onthebasisofgeothermaldevelopment,thispaperreviewsthegeothermalprogressduringthe"12thFive-YearPlan",andsummarizestheachievementsofhydrothermalgeothermalandhotdryrocksfromgeothermalsurveyandevaluationaspects.Finally,theauthorspredictthedevelopmenttrendofthefuturegeothermalresearchtobenefitgeothermalandhotdryrockresearch.