简介：ThelifeofimpregnatedBa-Wcathodeswithanewconstructionhavebeenevaluatedusinganacceleratedlifetestatthreedifferenttemperatures(1170℃,1130℃,1090℃)andconstantcurrentdensity(2A/cm~2).Accordingtotherelationshipoflifewithoperatingtemperatures,anacceleratedequationhasbeensetup.Thecathodelifeatnormaloperatingtemperatureisdeductedbasedontheacceleratedequation.Theresultsshowthatlifeofthenovelcathodeexceeds190,000houratacurrentdensityof2A/cm~2.

简介：AnewGraphicsProcessingUnit(GPU)parallelizationstrategyisproposedtoacceleratesparsefiniteelementcomputationforthreedimensionalelectromagneticanalysis.TheparallelizationstrategyisemployedbasedonanewcompressionformatcalledslicedELLFour(slicedELL-F).TheslicedELL-Fformat-basedparallelizationstrategyisdesignedforhasteningmanyaddition,dotproduct,andSparseMatrixVectorProduct(SMVP)operationsintheConjugateGradientNorm(CGN)calculationoffiniteelementequations.ThenewimplementationofSMVPonGPUsisevaluated.TheproposedstrategyexecutedonaGPUcanefficientlysolvesparsefiniteelementequations,espe-ciallywhentheequationsarehugesparse(sizeofmostrowsinacoefficientmatrixislessthan8).NumericalresultsshowtheslicedELL-Fformat-basedparallelizationstrategycanreachsigni?cantspeedupscomparedtoCompressedSparseRow(CSR)format.

简介：<正>Immunologicaltolerancetoselfisessentialformaintainingtheintegrityoftheorgansystems,anditsbreakdownmayleadtothedevelopmentofautoimmunediseases.Tolerancetoselfismaintainedthroughseveralmechanisms,whichincludenegativeselection,functionalinactivation(anergy)andsuppressionofautoreactivelymphocytes.However,onlynegativeselectionpermanentlyremovesautoreactivecellsthroughapoptosis.WhileithaslongbeenknownthatnegativeselectionrequiresaTcellreceptor(TCR)signal,itisunclearwhetheradeathligandsignalisalsoinvolved.TRAIL,thetumornecrosisfactor(TNF)-relatedapoptosis-inducingligand,isanewlydescribedmemberoftheTNFfamily.Unlikeotherdeathligandsof

简介：Atpresent,thegeopoliticallandscapeintheMiddleEastisundergoingaperiodofacceleratedtransformation,distinguishedbyarenewedgreat-powerrivalrybetweenRussiaandtheUnitedStatesandsupplementedbythecontestbetweenIranandSaudiArabia.AstheArabworldisnolongerunderaframeworkof“dualleadership,”divisionsamongregionalcampshavebecomeevenmoredistinct,makingregionalcohesionfurtherunlikely.Despiteitsoutstandingregionalinfluence,SaudiArabia’scapabilitiesstillfallshortofitsambitions.AlthoughtheKurdishindependencemovementsufferedamajorsetbackinsomeareas,ithasstillplayedanimportantroleintheevolutionofregionalgeopolitics.

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简介：我们试图与一致加速学习球状地对称的参考框架的热力学的性质，包括Rindler参考框架和一致地加速的参考框架的新类型的球状地对称的归纳。我们正式发现一个人不同于关于地平线热力学的一般研究，不能在平常的途径为他们的地平线获得热力学的法律，尽管有一个罐头定义区域熵(兜售熵的Bekenstein)。事实上，为一套一致地加速的观察员的普通地平线总是不存在，尽管兜售的Unruh温度仍然是明确的。这结果显示兜售的Unruh温度仅仅是运动学的效果，并且为地平线获得热力学的法律，一个人需要动力学的帮助。我们的结果根据从在声学的黑洞附近的各种各样的研究的那些。

简介：InthisworkweanalyzethecharacteristicsofquantumentangleinentoftheDiracfieldinnoninertialreferenceframesinthecontextofanewtypepseudo-purestate,whichiscomposedoftheBellstates.Thiswillhelpustounderstandtherelationshipbetweentherelativityandquantuminformationtheory.SomestateswillbechangedfromentangledstatesintoseparableonesaroundthecriticalvalueF=1/4,butthereisnosuchacriticalvalueforthevariableyrelatedtoaccelerationa.WefindthatthenegativityNas(ρ^TAAB1)increaseswithFbutdecreaseswiththevariabley、whilethevariationofthenegativityNb1b11(ρ^TB1B1B11)isoppositetothatofthenegativityNAB1(ρ^TAAB1).WealsostudythevonNeumannentropiesS(ρAB1)andS(ρB1B11)、WefindthattheS(ρAB1)increaseswithvariableybutS(ρB1B11)isindependentofit.However,bothS(ρAB1)andS(ρB1B11)firstdecreaseswithFandthenincreaseswithit.TheconcurrencesC(ρAB1)andC(ρB1B11)arealsodiscussed.WefindthattheformerdecreaseswithywhilethelatterincreaseswithybutbothofthemfirstincreasewithFandthendecreasewithit.

简介：Theinteractionsofasphericalflamewithanin-cidentshockwaveanditsreflectedshockwaveinaconfinedspacewereinvestigatedusingthethree-dimensionalreactiveNavier-Stokesequations,withemphasisplacedontheeffectofchemicalreactivityofmixtureontheflamedistortionanddetonationinitiationafterthepassageofthereflectedshockwave.Itisshownthatthespatio-temporalcharacteristicsofdetonationinitiationdependhighlyonthechemicalreactivityofthemixture.Whenthechemicalreactivityenhances,theflamecanbeseverelydistortedtoformareactiveshockbifurcationstructurewithdetonationsinitiatingatdifferentthree-dimensionalspatiallocations.Moreover,thedetonationinitiationwouldoccurearlierinamixtureofmoreenhancedreactivity.Theresultsrevealthatthedetonationsarisefromhotspotsintheunburnedregionwhichareinitiatedbytheshock-detonation-transitionmechanism.

简介：在这份报纸，我们基于插入内推的系数建议一个加速的搜索扩展方法(ASEM)有限元素方法，搜索扩展方法(SEM)和为semilinear获得多重答案的二格子的方法椭圆形的方程。这策略成功地是不仅实现了为semilinear的一个类获得多重解决方案椭圆形的边界值问题，而且还原剂昂贵的计算极大地。在1-D和2-D盒子的数字结果将显示出我们的途径的效率。

简介：BACKGROUND:Alongwithaging,antioxidaseactivitydecreasesandoxygen-derivedfreeradicalsgreatlyaccumulate,resultingincellularsenescence,orevencelldeath.Thisismanifestedbyhypomnesiaanddis-orderedmetabolismoffreeradicals.StudieshavereportedthatLongyanshenpolysaccharideshavethefunc-tionofantioxidationandimprovedbrainmemory.OBJECTIVE:ToobservetheeffectsofLongyanshenpolysaccharidesonfreeradicalmetabolisminbraintissuetoverifytheanti-agingmechanismsinsenescenceaccelerated-prone(SAMP8)mice.DESIGN,TIMEANDSETTING:Therandomized,controlled,biochemicalexperimentwasperformedintheDepartmentofPharmacologyandScientificExperimentalCenterofGuangxiMedicalUniversity(China)fromSeptember2005toJanuary2008.MATERIALS:FortySAMP8micewererandomizedintofourgroups:SAMP8controlgroup,aswellaslow-,mid-,andhigh-dosepolysaccharide,with10miceineachgroup.Tensenescenceaccelerated-resistant-prone(SAMR1)miceservedasthenormalcontrolgroup.Longyanshenpolysaccharides,extractedfromthemedicalplantLongyanshen,weresuppliedbytheDepartmentofPharmacology,GuangxiMedicalUniversity.Superoxidedismutase(SOD),glutathioneperoxidase(GSH-Px),malonaldehyde(MDA),nitricoxide(NO),andtotalproteintestkitwerepurchasedfromNanjingJianchengBioengineeringInstitute(China).METHODS:SAMP8micewereusedtoestablishadementiaanimalmodel.SAMP8andSAMR1controlmicewereadministered30mL/kgsaline.Thelow-,middle-,andhigh-dosepolysaccharidegroupswereadministered45,90,and180mg/kgLongyanshenpolysaccharides,respectively.Eachgroupwastreatedbyin-tragastricadministration,oncedaily,for50continuousdays.MAINOUTCOMEMEASURES:Onehourafterthelastadministration,mousebraintissueswerecollected,andretroorbitalbloodsamplingwasperformed.SpectrophotometrywasusedtomeasureSODandGSH-Pxactivity,aswellasMDAandNOconcentrationinseraandbrainsofSAMP8mice.RESULTS:

简介：Theboundaryelementmethod(BEM)isamainmethodforanalyzingtheinteractionsbetweenthewavesandthemarinestructures.AswiththeBEM,asetoflinearequationsaregeneratedwithafullmatrix,therequiredcalculationsandstorageincreaserapidlywiththeincreaseofthestructurescale.Thus,anacceleratedmethodwithalowstorageisdesirableforthewaveinteractionwithaverylargestructure.AsystematicreviewisgiveninthispaperfortheBEMforsolvingtheproblemofthewaveinteractionwithalargescalestructure.VariousintegralequationsarederivedbasedondifferentGreenfunctions,theadvantagesanddisadvantagesofdifferentdiscretizationschemesoftheintegralequationsbytheconstantpanels,thehigherorderelements,andthesplinefunctionsarediscussed.Forthehigherorderelementdiscretizationmethod,thespecialconcernsaregiventothenumericalcalculationsofthesingle-layerpotential,thedoublelayerpotentialandthesolidanglecoefficients.Foralargescalecomputationproblemsuchasthewaveinteractionwithaverylargestructureoralargenumberofbodies,theBEMswiththeFMMandpFFTaccelerationsarediscussed,respectively,includingtheprinciplesoftheFMMandthepFFT,andtheirimplementationsinvariousintegralequationswithdifferentGreenfunctions.Finally,somepotentialapplicationsoftheaccelerationmethodsforproblemswithlargescalecomputationsintheoceanandcoastalengineeringareintroduced.

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简介：3-hydroxy-3-methylglutaryl辅酶a(HMGCoA)reductase生产mevalonate，在胆固醇和必需品的合成的重要中介非甾醇isoprenoids。reductase通过被甾醇并且非调停的多重机制服从于反馈控制的过高的数量mevalonate的甾醇结束产品新陈代谢。这里，我将讨论为reductase的控制使一机制清楚些的最近的进展，它包含酶的快速的降级。某些甾醇的累积触发reductase的绑定到endoplasmic(嗯)膜蛋白质叫了Insig-1和Insig-2。在联系膜的ubiquitin连接酶的招募的Reductase-Insig有约束力的结果叫了gp78，它开始reductase的ubiquitination。这ubiquitination是为reductase从的识别和降级的应尽的反应嗯由cytosolic26Sproteasomes的膜。因此，reductase的加速甾醇的降级代表一般细胞的进程(嗯联系降级)怎么被用来控制一条重要新陈代谢的小径(胆固醇合成)的一个例子。

简介：Peltophorumdubiumseedsweresettoimbibewithfourtreatments,soakedwithsolutionCaptan0.2%under10and27℃,PEG6000-1.0MPaunder10and27℃.Foreachtreatmenttherewerefourreplicateswith40seedsincubatedin9-cmPetridisheswithdoublefilterpapermoistenedwithtestingsolution.Theimbibitioncurvesshowedthatthefinalweightincreasewerefrom70%to150%inthetreatmentswhenimbibitionenteredalagphase.Seedsweretestedforeffectsongerminationoffivetreatments:controlgroup(nonprimed),primedwithPEG6000-1.0MPaat10and27℃,primedwithCaptan0.2%at10and27℃.Foreachtreatment,therewerethreesub-treatments:seedsweresoakedindistilledwaterfor12,24and36hbeforetheenergytest.GerminationpercentagesofnonprimedseedsandprimedinPEG27℃soakedindistilledwaterduring12hwerethehighest,reaching100%.ThelowestgerminationpercentageoccurredprimedseedswithPEG600027℃andsoakedindistilledwaterduring36h,whichwasonly52%.GerminationmeantimeofprimedseedsinPEGat10℃,soaked24hwas1.08days,meantimeofprimedseedsinPEGat27℃soaked12hwas2.42days.Acceleratedageingresultsshowedlowornogerminationafterageing72h.Controlgrouphadahighergerminationpercentageandseedsweremoreresistanttodeteriorationthanthoseinprimedgroups,bothinPetridish(27℃)andvermiculate(roomtemperature).

简介：这研究在跟随加速的transepithelial的keratoconus角膜评估了临床的结果角膜的骨胶原cross-linking(CXL)(AvedroKXL?系统，麻省沃尔瑟姆，美国)超过一年后续。光连贯断层摄影术(10月)测量的分界线的吝啬的深度是205.19???吳????????<

简介：这份报纸建议贝叶斯的semiparametric与errors-in-covariates为二倍地审查的数据加速了失败时间模型。作者经由Dirichlet过程为未被遵守的covariates和回归错误的分布建模。而且，作者为可变选择把贝叶斯的套索途径递我们的semiparametric模型。作者为以后的计算开发Markov链蒙特卡罗策略。模拟研究被进行显示出建议方法的表演。作者也用PBC数据和ACTG175数据的分析表明方法的实现。

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简介：UnderType-IIprogressivelyhybridcensoring,thispaperdiscussesstatisticalinferenceandoptimaldesignonstepstresspartiallyacceleratedlifetestforhybridsysteminpresenceofmaskeddata.ItisassumedthatthelifetimeofthecomponentinhybridsystemsfollowsindependentandidenticalmodifiedWeibulldistributions.Themaximumlikelihoodestimations(MLEs)oftheunknownparameters,accelerationfactorandreliabilityindexesarederivedbyusingtheNewton-Raphsonalgorithm.Theasymptoticvariance-covariancematrixandtheapproximateconfidenceintervalsareobtainedbasedonnormalapproximationtotheasymptoticdistributionofMLEsofmodelparameters.Moreover,twobootstrapconfidenceintervalsareconstructedbyusingtheparametricbootstrapmethod.TheoptimaltimeofchangingstresslevelsisdeterminedunderD-optimalityandA-optimalitycriteria.Finally,theMonteCarlosimulationstudyiscarriedouttoillustratetheproposedprocedures.

简介：Thecalculationofsettlingspeedofcoarseparticlesisfirstlyaddressed,withacceleratedStokesiandynamicswithoutadjustableparameters,inwhichfarfieldforceactingontheparticleinsteadofparticlevelocityischosenasdependentvariablestoconsiderinter-particlehydrodynamicinteractions.Thesedimentationofasimplecubicarrayofsphericalparticlesissimulatedandcomparedtotheresultsavailabletoverifyandvalidatethenumericalcodeandcomputationalscheme.TheimprovedmethodkeepsthesamecomputationalcostoftheorderO(NlogN)asusualacceleratedStokesiandynamicsdoes.Then,morerealisticrandomsuspensionsedimentationisinvestigatedwiththehelpofMontCarlomethod.Thecomputationalresultsagreewellwithexperimentalfitting.Finally,thesedimentationoffinercohesiveparticle,whichisoftenobservedinestuaryenvironment,ispresentedasafurtherapplicationincoastalengineering.

简介：由由于Samokish扩大古典分析技术，在其它之中的Faddeev和Faddeeva，和Longsine和麦考密克，我们与含蓄的放气(PSD标志)证明preconditioned的集中是最陡峭的降下为解决Hermitian明确的概括特征值问题的方法。而且，我们导出PSD标志方法的集中的率的nonasymptotic估计。我们证明与移动的一种合适的选择，不定的shift-and-invertpreconditioner是局部地加速的preconditioner，并且是asymptotically最佳的它导致superlinear集中数字例子被举为解决从电子结构计算产生的性恶的Hermitian明确的概括特征值问题在PSD标志方法的集中行为上验证理论结果。当严密、照原尺寸时，preconditioned的集中证明在实际使用堵住最陡峭的降下方法仍然大部分逃避我们，我们相信在这份报纸介绍的理论结果使这些块方法的集中行为的改进理解清楚些。