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  • 简介:Inthecomingyearslifeexpectancyisexpectedtoincreaseandwiththisthepercentageofthepopulationaboveage65willgrow.Patientsabove65makeupmorethantwothirdsofthosecurrentlydiagnosedwithgastrointestinalmalignancies.Availableevidencebasedmedicinedoesnotfocusontheaveragepatient,abovetheage70,encounteredineverydaypractice.Mostguidelinesandclinicaltrialsarenotdesignedtotakeintoaccountthespecialconsiderationsneededwhentreatingtheelderlysuchasfunctionalstatus,comorbidities,polypharmacy,lifeexpectancy,andsocialsupport.Themajorityofavailabledataisbasedonretrospectivereviewsorsubsetanalysesoflargerstudieswheretheelderlyrepresentafractionofthestudiedpopulation.Thisreviewfocusesonthetoxicitiesandtolerabilityofcurrentstandardtherapiesfornoncolorectalgastrointestinalmalignancies,includinggastroesophageal,pancreatic,bileductandhepatocellularcancersintheelderly.Withcarefulpatientselectionandgeriatricassessmenttheelderlycansafelybenefitfromstandardtherapiesofferedtoyoungerpatients.

  • 标签: 恶性肿瘤 结直肠癌 消化系统 老年人 胃肠道 治疗
  • 简介:Datacollectedonthesurfaceoftheearthoftenhasspatialinteraction.Inthispaper,anon-isotropicmixingspatialdataprocessisintroduced,andundersuchaspatialstructureanonparametrickernelmethodissuggestedtoestimateaspatialconditionalregression.Undermildregularities,sufficientconditionsarederivedtoensuretheweakconsistencyaswellastheconvergenceratesforthekernelestimator.Ofinterestarethefollowing:(1)Alltheconditionsimposedonthemixingcoefficientandthebandwidtharesimple;(2)Differentlyfromthetimeseriessetting,thebandwidthisfoundtobedependentonthedimensionofthesiteinspaceaswell;(3)Forweakconsistency,themixingcoefficientisallowedtobeunsummableandthetendencyofsamplesizetoinfinitymaybeindifferentmannersalongdifferentdirectioninspace;(4)However,tohaveanoptimalconvergencerate,fasterdecreasingratesofmixingcoefficientandthetendencyofsamplesizetoinfinityalongeachdirectiona

  • 标签: Bandwidth kernel estimator mixing non-isotropic SPATIAL
  • 简介:Somespecificnon-isotropicJacobiapproximationsinmultiple-dimensionsareinvestigated,whichareusedfornumericalsolutionsofdifferentialequationsonvariousunboundeddomains.Theconvergenceofproposedschemesareproved.Someefficientalgorithmsareprovided.Numericalresultsarepresentedtoillustratetheefficiencyofthisnewapproach.

  • 标签: 无界域 非等方性雅各比近似值 边界问题 微分方程
  • 简介:全部的推迟的微粒(TSP)样品沿着Qingdao的海岸在三个地点被收集,中国,在前并且在在2002年3月的主要尘暴期间。为比较,PM_(10)(有空气动力学的直径的微粒物质不到10μm)样品被收集三个地点赎回。词法观察和体积和单个粒子的组合分析被使用扫描与为TSP和PM_(10)的散X光检查系统(SEM/EDX)取样的一个精力装备的电子显微镜学执行。结果证明形态学的不同类型的粒子有类似的形态学的不同元素的作文,而是粒子总是没为非灰尘样品有一样的元素的作文。非灰尘粒子的Themorphology和作文在不同地点是不同的。分数维、球形的粒子为非灰尘样品主要在粗粒级存在,当时在好模式(<10μm)有絮状物,一起结队并且包含外壳的元素的好粒子形成。与非灰尘粒子相比,尘粒以形态学,颗粒大小和作文是更同类的。有andwell分布式的尺寸在灰尘样品统治了的不规则的形状的粒子,包含象Mg那样的外壳的元素,艾尔,Si,Ca,Fe,等等。高硫内容显示了那同类并且多相反应在Qingdao的特定的环境发生在尘粒的表面上。

  • 标签: 气溶胶 颗粒污染物 电子显微镜扫描 灰尘 大气污染
  • 简介:预兆的deconvolution算法(PD)基于秒顺序统计,假设primaries和multiples是含蓄地直角的。然而,地震数据通常不在实践满足这个假设。自从地震数据(primaries和multiples),有non-Gaussian分布,在这篇论文我们在场由最大化恢复primaries的non-Gaussianity的一个改进预兆的deconvolution算法(IPD)。合成、真实的地震数据集上的IPD方法的应用证明建议方法获得有希望的结果。

  • 标签: 预定去卷积 多重稀薄化 地震数据 最大值
  • 简介:Anewalgorithmforsolvingthethree-dimensionalelasticcontactproblemwithfrictionispresented.Thealgorithmisanon-interiorsmoothingalgorithmbasedonanNCPfunction.Theparametricvariationalprincipleandparametricquadraticprogrammingmethodwereappliedtotheanalysisofthree-dimensionalfrictionalcontactproblem.Thesolutionofthecontactproblemwasfinallyreducedtoalinearcomplementarityproblem,whichwasreformulatedasasystemofnonsmoothequationsviaanNCP-function.Asmoothingapproximationtothenonsmoothequationswasgivenbytheaggregatefunction.ANewtonmethodwasusedtosolvetheresultingsmoothingnonlinearequations.Thealgorithmpresentediseasytounderstandandimplement.ThereliabilityandefficiencyofthisalgorithmaredemonstratedbothbythenumericalexperimentsofLCPinmathematicalwayandtheexamplesofcontactproblemsinmechanics.

  • 标签: NCP-函数 光滑算法 集成功能 参数变化原则 弹性接触 摩擦接触
  • 简介:Settlingvelocityisafundamentalparameterinsedimenttransportdynamics.ForuniformPar-ticles,thereareabundantformulasforcalculationoftheirsettlingvelocities.Butinnaturalfields,sedi-mentconsistsofnon-uniformparticles.Theinteractionamongparticlesiscomplexandshouldnotbeneg-lected.Inthispaper,basedontheanalysisofsettlingmechanismofnon-cohesiveandnon-uniformparti-cles,atheoreticalmodeltodescribesettlingmechanismisproposed.Besidessuspensionconcentrationandupwardturbulentflowcausedbyotherparticles,collisionamongparticlesisanothermainfactorinflu-encingsettlingvelocity.Byintroducingthecollisiontheory,equationsoffallvelocitybeforecollision,colli-sionprobability,andfallvelocityaftercollisionareestablished.Finally,aformulausedtocalculatetheset-tlingvelocityofnon-cohesiveparticleswithwidegraingradationispresented,whichagreeswellwiththeexperimentaldata.

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  • 简介:Non-transferreddcarcplasmageneratorsarewidelyusedinmaterialsprocessing.Theyaregenerallyconsideredsteadily-operatingdevises.However,unsteadyphenomenadoexistinthem,andmaycausenon-idealeffectsinprocesseswhichrequirehighcontrollabilityandreproducibility.Theseunsteadyphenomenacancauseparameterfluctuationsinthearcandtheplasmajet,someofwhichhavebeenstudiedinrecentyears.Severaltypesandmechanismsofthesephenomenahavebeenidentified.Thispaperreviewst...

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  • 简介:Inthisarticle,itispointedoutthattheinformationnon-modifiabilityandinformation“fidelity”involvedin“informationdeterminacy”isamomentousrevolutioninepistemologicalconception.Byeliminatingtheconstrictionofquantitativestability,thereexistpeculiarinformationandperiodicityundernonlinearinstability.ThecommensurabilitybyWengWenbomaybeexplainedbyapplyingspecialcharactersofpeculiarinformation.Onevolutionofsubstance,thegeneralrulesforquantitativeanalysescannotbeextendedintoprocessofpeculiarinformation.Therefore,thecontemporaryscienceshavenotresolvedsomeimportantproblemsinevolutionofsubstancesuchas“time”,peculiarity,non-inertialsystem,andfabricatedinformationinquantitativeanalyses.Thenaturalcharactersandnon-modifiabilityofinformationhaveessentiallyprovedthatitisanepistemologicalmisunderstandingtoconsidertheinformationanalysisinmodern“informationscience”thesameasquantitativeanalysisinthecontemporarysciences.Thatis,“information”cannotbeidenticalto“quantity”.

  • 标签: 信息决策 内容演化 非潮间系统 自然灾害 预测方法
  • 简介:Inthispaper,addedresistancesactingonahullofnonballastwatership(NBS)inhighwavesisdiscussed.ThenonballastwatershipsweredevelopedatthelaboratoryoftheauthorsatOsakaPrefectureUniversity,Japan.Inthepresentpaper,theperformancesofthreekindsofbowshapesdevelopedfortheNBSweretheoreticallyandexperimentallyinvestigatedtofindthebestoneinhighwaves.Inpreviouspapers,anoptimumbowshapefortheNBSwasdevelopedincalmwaterandinmoderatedwaves.Fora2mmodelforexperimentsandcomputations,thewaveheightis0.02m.Thismeansthatthewaveheightis15%ofthedraftoftheshipinfullloadconditions.Inthispaper,addedresistancesinhighwavesupto0.07mfora2mmodelor53%ofthefullloaddraftareinvestigated.Insuchhighwaveslinearwavetheorieswhichhavebeenusedinthedesignstageofashipforalongtimemaynotworkwellanymore,andexperimentsaretheonlyeffectivetooltopredicttheaddedresistanceinhighwaves.Withthecomputationsforwaves,theshipisinafullycapturedconditionbecauseshorterwaves,λ/Lpp〈0.6,areassumed.

  • 标签: KEYWORDS added resistance non BALLAST water
  • 简介:AIMTo调查在patients.METHODSNon-DSEK在接枝拒绝率,和它的全面程序的有效性上剥去endothelialkeratoplasty(non-DSEK)的non-Descemet的影响在64个病人,和程序的结果的65只眼睛上被执行包括接枝的拒绝事件,失败和脱臼,最好改正的视觉尖酸(BCVA),endothelial房间密度(ECD),和另外的复杂并发症,是65看的分析retrospectively.RESULTSOf,63从bullouskeratopathywi恢复了吝啬的后续时间是26.4mo(范围,6-84mo)。吝啬的BCVA在外科以后在1y在3mo,在6mo的0.46logMAR,和0.37logMAR外科手术前地从1.70logMAR改善了到0.54logMAR。成功地经历了镜子的显微镜的检查的25个病人的手术后的施主ECD是1918<

  • 标签: endothelial keratoplasty non-Descemet 脱衣 endothelial keratoplasty endothelial 机能障碍 Descemet 膜