简介：碱的特征激活炉渣(AAS)，港口陆地水泥(PC)被观察在上多尺度，裂缝和破裂节与肉眼，和SEM被观察，AFM被用来在测微计上学习PC和AAS之间的结构形态学差别到nano米规模。试验性的结果显示AAS浆糊有象骨折质地一样的土壤，它由组成主要C-S-H胶化但是晶体的缺乏，并且它有一个很强壮的趋势缩小并且裂开。AAS浆糊比PC稠密得多、更同类，并且在AAS粘贴在nano上放大C-S-Hnano粒子小得多并且包装比PC浆糊稠密的大部分。

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简介：TherecoveryofAubyactivatedcarbonfibers(ACFs)wascarriedoutina40mmdiameter,1200mmheightfluidizedbedTheratesofreactionofthefunctionalfiberswithAu3+inthepureaurumsolutionandintheaurum-containingwastewaterweremeasuredrespectivelyatthedifferentsolutionfiowrates,andcomparedwiththeresultsunderthestaticsolutionconditions.Experimentalresultsindicatedthatthereactionratesinfluidizationarenotablyhigherthanthoseinthestaticstateandincreasewiththeincreaseofsolutionflowrate.Itdemonstratesthatthethicknessoftheconcentrationboundarylayerisdecreasedandauniformtemperaturefieldisestablishedinthebedduetoincreasingoftheturbulentextentwiththerelativefiber/solutionvelocity.

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简介：OrganicchelatingreagentinfluencesupontheredoxadsorptionofactivatedcarbonfibertowardsAu3-weresystematicallyinvestigated.TheexperimentalresultsindicatedthatthepresenceoforganicchelatingreagentonactivatedcarbonfiberstronglyaffectsadsorptioncapacityofactivatedcarbonfibertowardsAu3+.Thereduction-adsorptionamountofAu3+increasedthreetimesbythepresenceof8-quinolinol.Furthermore,Thereduction-adsorptionamountofAu3+dependedonthepHvalueofadsorptionandtemperature.

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简介：Receptor-ligandinteractionsinbloodflowarecrucialtoinitiatesuchbiologicalprocessesasinflammatorycascade,plateletthrombosis,aswellastumormetastasis.Tomediatecelladhesion,theinteractingreceptorsandligandsmustbeanchoredontotwoapposingsurfacesoftwocellsoracellandasubstratum,i.e.,two-dimensional(2D)binding,whichisdifferentfromthebindingofasolubleligandinfluidphasetoareceptor,i.e.,three-dimensional(3D)binding.Whilenumerousworkshavebeenfocusedon3Dkineticsofreceptor-ligandinteractionsintheimmunesystem,2Dkineticsanditsregulationshavebeenlessunderstood,sincenotheoreticalframeworkorexperimentalassayswereestablisheduntil1993.Notonlydoesthemolecularstructuredominate2Dbindingkinetics,buttheshearforceinbloodflowalsoregulatescelladhesionmediatedbyinteractingreceptorsandligands.Here,weprovideanoverviewofcurrentprogressin2Dbindingandregulations,mainlyfromourgroup.Relevantissuesoftheoreticalframeworks,experimentalmeasurements,kineticratesandbindingaffinities,andforceregulationsarediscussed.

简介：为计划接近的充分分离的放松的二个班在房间熵不平等上介绍研究分级的能量守恒定律。计划的主要优点；有一个生硬来源术语的令人放松的系统的构造的评论；结论。

简介：AcomputerscientistatWashingtonUniversityinSt.Louishasdevelopedawaytocoaxcellstodonaturalthingsunderunnaturalcircumstances,whichcouldbeusefulforstemcellresearch,genetherapyandbiofuelproduction.MichaelBrent,theHenryEdwinSeverProfessorofEngineeringintheSchoolofEngineering&

简介：AbstractChronic obstructive pulmonary disease (COPD), characterized by persistent and not fully reversible airflow restrictions, is currently one of the most widespread chronic lung diseases in the world. The most common symptoms of COPD are cough, expectoration, and exertional dyspnea. Although various strategies have been developed during the last few decades, current medical treatment for COPD only focuses on the relief of symptoms, and the reversal of lung function deterioration and improvement in patient’s quality of life are very limited. Consequently, development of novel effective therapeutic strategies for COPD is urgently needed. Stem cells were known to differentiate into a variety of cell types and used to regenerate lung parenchyma and airway structures. Stem cell therapy is a promising therapeutic strategy that has the potential to restore the lung function and improve the quality of life in patients with COPD. This review summarizes the current state of knowledge regarding the clinical research on the treatment of COPD with mesenchymal stem cells (MSCs) and aims to update the understanding of the role of MSCs in COPD treatment, which may be helpful for developing effective therapeutic strategies in clinical settings.

简介：AbstractGlucagon is a potent glucose-elevating hormone that is secreted by pancreatic α- cells. While well-controlled glucagon secretion plays an important role in maintaining systemic glucose homeostasis and preventing hypoglycaemia, it is increasingly apparent that defects in the regulation of glucagon secretion contribute to impaired counter-regulation and hyperglycaemia in diabetes. It has therefore been proposed that pharmacological interventions targeting glucagon secretion/signalling can have great potential in improving glycaemic control of patients with diabetes. However, despite decades of research, a consensus on the precise mechanisms of glucose regulation of glucagon secretion is yet to be reached. Second messengers are a group of small intracellular molecules that relay extracellular signals to the intracellular signalling cascade, modulating cellular functions. There is a growing body of evidence that second messengers, such as cAMP and Ca2+, play critical roles in α-cell glucose-sensing and glucagon secretion. In this review, we discuss the impact of second messengers on α-cell electrical activity, intracellular Ca2+ dynamics and cell exocytosis. We highlight the possibility that the interaction between different second messengers may play a key role in the glucose-regulation of glucagon secretion.

简介：某些疾病被知道引起变化在物理并且房间的biomechanical性质。这些在其它之中包括癌症，疟疾，和镰刀房间贫血症。典型地，如此的物理性质变化能导致房间僵硬的几褶层增加或减少，它是重要的并且能导致严重病理和最终的灾难的故障身体功能。当有时开发了生物化学、生物的试金检测疾病的发作或存在，总是有需要开发更快速、精确、敏感的方法检测并且诊断疾病。Biomechanical性质变化能起一个重要作用在这方面。因此，对疾病biomechanics的研究不能仅仅给我们位于疾病前进下面的机制的深入的知识，但是能也为察觉和诊断用作一个强大的工具。这篇文章提供一些卓见进机会因为在疾病的发作或前进期间在细胞的机械性质换掉怎么重要，能为察觉和诊断作为有用工具被利用。我们将也展示已经被开发了执行如此的察觉和诊断的几种技术。

简介：Thecurrentconceptof“AdoptiveTCellImmunotherapyofCancer”isquitedifferentfromhowitwasoriginallyconceived．Withthedevelopmentofmoderntechnologyinmolecularbiology,cellbiology，immunologyandbiochemistryduringthelasttwentyyearsorso，adoptiveimmunotherapyhasgrownfromitsinitialformofasimple“bloodcelltransfer”intoitspresentprocesswhichinvolveshostvauccination，effectorcellactivation／polarizationandgeneticmodification．Withtheuseofimmuneadjuvantsandtheidentification／characterizationoftumor-reactiveTcellsubsets，orincombinationwithothertherapeuticstrategies，adoptivelytransferredTcellshavebecomemuchmorepotentinmediatingtumorregression．Inaddition，studiesonthetraffickingofinfusedTcells，celltransferperformedinlymphopenicmodels，aswellasthediscoveryofnoveltechniquesinimmunemonitoringforthegenerationofeffectorcellsinvitroandaftercelltransferinvivohaveprovidedusefultoolstofurtherimprovethetherapeuticefficacyofthisapproach．ThisarticlewillreviewtheserelatedaspectsofadoptiveTcellimmunotherapyofcancerwithspecificcommentsoncertaincriticalareasintheapplicationofthisapproach．Withtherapidlyevolvingadvancesinthisarea，itishopedthatthiscellularimmunologictherapyasitwasconceptualizedinthepast，canbecomemoreusefulinthetreatmentofhumancancerinthenearfuture．

简介：背景知识：Cell与开源CellBroadbandEngine（本文简称Cell）是一款异构（heterogeneous）的多核CPU，其目前主要用在PS3和IBM的CellBladeServer上，著名的Roadrunner就是使用了这款CPU。IBM在发布Cell处理器技术细节的时候，就表明了IBM对开放源代码计算设计的支持。通常情况下，芯片厂商会共享部分系统设计，以鼓励其它厂商开发相关应用程序或兼容芯片。

简介：超声能不仅在检查，而且在治疗被使用，特别在癌症的治疗。Sonodynamic治疗是使用超声提高作为sonosensitizers知道的代理人的细胞毒素的效果的一个试验性的癌症治疗方法。它在vitro并且在vivo被测试了。超声能在一些直接改变房间膜渗透的条件下面渗透织物和房间，从而在某度允许外长的分子的交货进房间。超声能禁止增长或在vitro或在vivo导致癌症房间的apoptosis。低频率的显示的最近的研究和低紧张的超声能导致房间apoptosis，它能被sonodynamic敏感加强，microbubbles，化学疗法的药等等。超声的大多数类型通过导致癌症房间的apoptosis压制了癌症房间的增长。apoptosis的机制不是清楚的。在这评论，我们将集中于并且由超声讨论癌症房间apoptosis的正式就职的机制。

简介：Onthebasisofthequantizationofmesoscopicbiologicalcellequivalentcircuit,westudiedthequantumfluctuationsofvoltageandcurrentofmesoscopicbiologicalcellequivalentcircuitasfinitetemperaturebyBogoliuovtransformation.Theresultshowsthatthequantumfluctuationsofvoltageandcurrentnotonlyrelatewiththeparametersofequivalentcircuit,temperature,butalsodecaywithtime.Thisresultmayhavesignificantvalueonthedesignandapplicationofthebio-electronicapparatus.

简介：房间趋于在本国的纸巾形成层次结构。在象癌症球状体和胚胎的身体那样的vitro的房间总数的形成提供一个唯一的工具在vivo学习机械性质和他们的对应物的生物行为/功能。在这份报纸，我们考察最先进的试验性的途径在vitro估计机械性质和房间总数的机械地导致的回答。这些途径根据装载形式被分类进五个范畴，包括micropipette渴望，centrifugation，装载的压缩，底层膨胀，和液体砍装载。我们讨论了每条途径，和潜在的生物医学的应用的优点和劣势。房间总数的机械行为的理解提供卓见给在生物功能的房间和正直之间的物理相互作用，它可以为象atheromatosis和癌症那样的疾病启用机械干预。

简介：Rabbitlimbalcornealepithelialcells,cornealendothelialcellsandkeratocyteswereculturedonamnioticmembrane.Phasecontrastmicroscopeexaminationwasperformeddaily.Histologicalandscanelectronmicroscopicexaminationswerecarriedouttoobservethegrowth,arrangementandadhesionofcultivatedcells.Resultsshowedthatthreecornealcelltypesseededonamnioticmembranegrewwellandhadnormalcellmorphology.Culturedcellsattachedfirmlyonthesurfaceofamnioticmembrane.Cornealepithelialcellsshowedsingularlayerorstratification.Cellboundarieswereformedandtightlyopposed.Cornealendothelialcellsshowedcobblestoneorpolygonalmorphologiccharacteristicsthatappeareduniforminsize.Thecellulararrangementwascompact.Keratocyteselongatedandshowedtriangleordendriticmorphologywithmanyintercellularjointswhichcouldformnetworks.Inconclusion,amnioticmembranehasgoodscaffoldproperty,diffusioneffectandcompatibilitywithcornealcells.Thebasementmembranesideofamnioticmembranefacilitatedthegrowthofcornealepithelialcellsandendothelialcellsandcelljunctionsweretightlydeveloped.Thespongylayerofamnioticmembranefacilitatedthegrowthofkeratocytesandintercellularjointswererich.Amnioticmembraneisanidealbiomaterialforlayeringtissueengineeredcornea.

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简介：Ananomeshhasbeendevelopedthatnearlytriplessolarcellefficiency.Theresearchteammanagedtoreducethereflectivityofthematerialsused,effectivelyincreasingtheamountofcapturedlight.Inadditiontothis,thenewsolarcellsarealsomuchthinnerthancurrentonesonthemarket.Thestructureiscreatedbysandwichingmetalwithnanomeshandisbeingcalled'PlasomnicCavity