简介：频率当横梁前者收到宽带信号时，不变的反应算法为在高频率克服信号失真被建议。在这个方法，参考书横梁模式的重量向量第一被设计，然后重量向量在主要接近参考书反应的频率亚乐队的横梁反应什么时候被计算由，优化了方法或适应方法。由这个方法，在每sub-bandcan的横梁模式几乎被使不变。作为结果，收到啁啾信号能被改进。由于到途径的适应方法的采纳优化向量，它没有限制数组格式和元素择向性，和方法能广泛地被使用。

简介：Thetransmissionantennasofcooperativesystemsarespatiallydistributedonmultiplenodes,sothereceivedsignalcanbeasynchronousduetopropagationdelays.Areceivingschemeforcooperativerelaynetworksisproposed,multipleasynchronoussignalsarereconstructedatthereceiverbyforwardandbackwardinterferencecancellation,whichcanobtaingainsofcooperativetransmissiondiversitywithobviousdelayandwithnorequiringtimingsynchronizationororthogonalchannelizationbetweenrelays.Analysisandsimulationshowthatthebiterrorrate(BER)oftheproposedschemeissimilartoAlamouticode,andtheschemehasthediversityorderoforthogonaltransmissionschemeaccompaniedbyminimalBERlosses.Itisdemonstratedthattheperformancecanbefurtherimprovedbyaddinganerrorcorrectingcode(ECC).

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简介：Ifeelthatthisawardwasnotmadetomeasaman,buttomywork—alifesworkintheagonyandsweatofthehumanspirit,notforgloryandleastofallforprofit,buttocreateoutofthematerialsofthehumanspiritsomethingwhichdidnotexistbefore,sothisawardisonlymineintrust.Itwillnotbedifficulttofredadedi-cationforthemoneypartofitcommensuratewiththepurposeandsignificanceofitsorigin.ButIwouldliketodothesamewiththeac-claimtoo,byusingthismomentasa...

简介：AbstractBackground:Post-operative pneumonia (POP) is a common complication of lung cancer surgery, and muscular tissue oxygenation is a root cause of post-operative complications. However, the association between muscular tissue desaturation and POP in patients receiving lung cancer surgery has not been specifically studied. This study aimed to investigate the potential use of intra-operative muscular tissue desaturation as a predictor of POP in patients undergoing lung cancer surgery.Methods:This cohort study enrolled patients (≥55 years) who had undergone lobectomy with one-lung ventilation. Muscular tissue oxygen saturation (SmtO2) was monitored in the forearm (over the brachioradialis muscle) and upper thigh (over the quadriceps) using a tissue oximeter. The minimum SmtO2 was the lowest intra-operative measurement at any time point. Muscular tissue desaturation was defined as a minimum baseline SmtO2 of <80% for >15 s. The area under or above the threshold was the product of the magnitude and time of desaturation. The primary outcome was the association between intra-operative muscular tissue desaturation and POP within seven post-operative days using multivariable logistic regression.The secondary outcome was the correlation between SmtO2 in the forearm and that in the thigh.Results:We enrolled 174 patients. The overall incidence of muscular desaturation (defined as SmtO2 < 80% in the forearm at baseline) was approximately 47.1% (82/174). The patients with muscular desaturation had a higher incidence of pneumonia than those without desaturation (28.0% [23/82] vs. 12.0% [11/92]; P = 0.008). The multivariable analysis revealed that muscular desaturation was associated with an increased risk of pneumonia (odds ratio: 2.995, 95% confidence interval: 1.080-8.310, P = 0.035) after adjusting for age, American Society of Anesthesiologists status, Assess Respiratory Risk in Surgical Patients in Catalonia score, smoking, use of peripheral nerve block, propofol, and study center.Conclusion:Muscular tissue desaturation, defined as a baseline SmtO2 < 80% in the forearm, may be associated with an increased risk of POP.Trial registration:No. ChiCTR-ROC-17012627.

简介：Theanalog-to-informationconvertor(AIC)isasuccessfulpracticeofcompressivesensing(CS)theoryintheanalogsignalacquisition.Thispaperpresentsamulti-narrowbandsignalssamplingandreconstructionmodelbasedonAICandblocksparsity.Toovercomethepracticalproblems,theblocksparsityisdividedintouniformblockandnon-uniformblocksituations,andtheblockrestrictedisometrypropertyandsub-samplinglimitindifferentsituationsareanalyzedrespectivelyindetail.TheoreticalanalysisprovesthatusingtheblocksparsityinAICcanreducetherestrictedisometricconstant,increasethereconstructionprobabilityandreducethesub-samplingrate.Simulationresultsshowthattheproposedmodelcancompletesub-samplingandreconstructionformulti-narrowbandsignals.ThispaperextendstheapplicationrangeofAICfromthefiniteinformationratesignaltothemulti-narrowbandsignalsbyusingthepotentialrelevanceofsupportsets.Theproposedreceivingmodelhaslowcomplexityandiseasytoimplement,whichcanpromotetheapplicationofCStheoryintheradarreceivertoreducetheburdenofanalog-todigitalconvertor(ADC)andsolvebandwidthlimitationsofADC.

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简介：Objective:Anlotinibhydrochlorideisamultitargettyrosinekinaseinhibitorthattargetsvascularendothelialgrowthfactorreceptor,fibroblastgrowthfactorreceptor,platelet-derivedgrowthfactorreceptor,c-Kit,andc-MET;therefore,itexhibitsbothantitumorandanti-angiogeneticactivities.AphaseIIItrialhasshownthatanlotinibimprovedprogression-freesurvival(PFS)andoverallsurvival(OS)inpatientswithadvancednon-smallcelllungcancer(NSCLC),whopresentedwithprogressivediseaseorintoleranceafterstandardchemotherapy.Thisstudyaimedtoanalyzethecharacteristicsofpatientsreceivinganlotinibtreatmenttodeterminethedominantpopulationswhoarefitforthetreatment.Methods:DatawerecollectedfromMarch2015toJanuary2017fromarandomized,double-blind,placebo-controlled,multicenter,phaseIIItrialofanlotinib(ALTER0303).Atotalof437patientswereenrolledandrandomlyallocated(2:1)totheanlotinibandplacebogroups.Kaplan–Meieranalysisandlog-ranktestwereperformedtocomparePFSandOS.Coxproportionalhazardsmodelwasadoptedformultivariateprognosticanalysis.Results:Multivariateanalysisindicatedthathighpost-therapeuticperipheralbloodgranulocyte/lymphocyteratioandelevatedalkalinephosphataselevelswereindependentriskfactorsforPFS.Meanwhile,elevatedthyroid-stimulatinghormone,bloodglucose,andtriglyceridelevels;hypertension;andhand–footsyndromewereindependentprotectivefactorsofPFS.Highposttherapeuticperipheralbloodgranulocyte/lymphocyteratio,anEasternCooperativeOncologyGroup(ECOG)score≥2,andthesumofthemaximaltargetlesionlengthatbaselinewereindependentriskfactorsofOS,andhypertriglyceridemiawasanindependentprotectivefactorofOS.Conclusions:ThisstudypreliminarilyexploredthepossiblefactorsthataffectedPFSandOSafteranlotinibtreatmentinpatientswithadvancedrefractoryNSCLC,andthebaselinecharacteristicsofthetherapeuticallydominantpopulationswere

简介：Objective:Toinvestigatetheinfluenceofdifferentrightventricular(RV)pacingsitesonQRSwidth,andtoprovideapotentialreferencesiteforpermanentrightventricularpacinginpatientsimplantedwithpermanentpacemakers.PacingatthesitewiththeshortestQRSdurationmayreducethedeleteriouseffectsofRVpacingonLVfunction,andthushavingbeneficialeffectsonpatient’soutcome.Methods:AllconsecutivepatientswhowereplannedtohavepermanentpacemakerimplantationforaClassIorIIaindicationatourdepartmentfromOctober2010toJuly2012werescreenedfortheparticipationinthisprospective,singlecenter,non-randomizedstudy.ThebaselinesurfaceECGwasanalyzedforQRSwidthandmorphology,respectively.DuringtheimplantationprocedurepatientsweretransientlypacedatdifferentRVlocations(rightventricularapex,rightventricularinflowtract[RVIT],midseptum,highseptumandrightventricularoutflowtract[RVOT])beforetheleadwasplacedatitsfinalposition.Duringpacingatthedifferentpositionsthesurface12-leadsECGwasrecorded.BasedonthesurfaceofECGQRSdurationandmorphologyofthedifferentrightventricularpacingsiteswereanalyzedandcomparedwithbaselineandtoeachother.Results:Atotalof216patients(39%female,meanage69±13years,higherdegreeAVblock30.5%)wasenrolledinthestudy.PacedQRSdurationwassignificantlydifferentbetweenallrightventricularpacingsitescomparedwiththebaselineECG(baseline:106ms±21ms;meanpaced:158ms±16ms;p<0.001).RVApacingshowedthewidestQRS(168ms±16ms).QRSdurationwithRVITpacingwas166ms±15ms,andthatwithRVOTpacingwas165ms±15ms,respectively.QRSdurationwasnotsignificantlydifferentbetweenthesethreepositions.Mid-septalpacingshowedthenarrowestQRS(139ms±19ms)comparedtoallotherpacingsites(p<0.001).Pacingatthehigh-septumshowedabroaderQRS(153ms±14ms)thanthatpacingatthemid-septum.Comparedtootherrightventricularpacingsites

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简介：<正>AttheinvitationoftheChineseAssociationforInternationalUnderstanding(CAFIU),a10-memberJCI(JuniorChamberInternationalJapan)delegationheadedbyAgeharaYasumaro,ChairmanofJCIJapan-ChinaFriendshipAssociationandHayashiHiroshi,Vice-ChairmanofJCIJapan-ChinaFriendshipAssociationvisitedBeijingfromMay19-22.JuniorChamberofJapan(JCforshort)wasestablishedin1951andithas698chaptersacross

简介：AbstractBackground:The effects of keto acid (KA) supplements on Chinese patients receiving maintenance hemodialysis (MHD) are unclear. This study aimed to evaluate the effects of KA supplementation on nutritional status, inflammatory markers, and bioelectric impedance analysis (BIA) parameters in a cohort of Chinese patients with MHD without malnutrition.Methods:This was a prospective, randomized, controlled, single-center clinical study conducted in 2011 till 2014. Twenty-nine patients with MHD were randomly assigned to a control (n = 14) or a KA (n = 15) group. The control group maintained a dietary protein intake of 0.9 g/kg/day. The KA group received additional KA supplement (0.1 g/kg/day). BIA was used to determine the lean tissue mass, adipose tissue mass, and body cell mass. The patients’ nutritional status, dialysis adequacy, and biochemical parameters were assessed at the ends of the third and sixth months with t test or Wilcoxon rank-sum test.Results:The daily total energy intake for both groups was about 28 kcal/kg/day. After 6 months, the Kt/V (where K is the dialyzer clearance of urea, t is the dialysis time, and V is the volume of the distribution of urea) was 1.33 ± 0.25 in KA group, and 1.34 ± 0.25 in the control group. The median triceps skin-fold thickness in KA group was 12.00 and 9.00 mm in the control group. In addition, the median hand-grip strength in KA group was 21.10 and 25.65 kg in the control group. There were no significant differences between the groups with respect to the anthropometry parameters, dialysis adequacy, serum calcium and phosphorus levels, inflammatory markers, and amino-acid profiles, or in relation to the parameters determined by BIA. Both groups achieved dialysis adequacy and maintained nutritional status during the study.Conclusions:In this cohort of Chinese patients with MHD, the patients in the control group whose dietary protein intake was 0.9 g/kg/day and total energy intake was 28 kcal/kg/day, maintained well nutritional status during study period. The KA supplement(0.1 g/kg/day) did not improve the essential amino acid/non-essential amino acid ratio, nor did it change the patients’ mineral metabolism, inflammatory parameters, or body compositions.

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简介：瞄准：低剂量的阿司匹林的使用很好被建立阻止心血管的疾病事件。然而，上面的胃肠的流血的发生和有它的使用的预言者(UGIB)是未知的。我们有希望地在低剂量的阿司匹林用户学习了消化剂溃疡的发生和结果。方法：有低剂量的阿司匹林上的冠的动脉疾病(CAD)的991个病人的一个总数是有希望地跟随起来的为出现和UGIB的首先就医的事件的临床的特征的二年了。结果：UGIB有一个双性人有45%发生在四月阿司匹林开始以内的形式的表示并且每年有1.5%的全面流行。没有UGIB相关的死亡。高血压(或=4.6，95%CI1.5-14.7，P=0.009)，消化剂溃疡的历史(或=3.1，95%CI1.1-9.0，P=0.039)，第三级的教育(或=3.08，95%CI1.1-9.0，P=0.039)并且更高瘦的身体质量(P=0.016)独立因素与UGIB被联系。硝酸盐的使用没减少UGIB。结论：在有长期的低剂量的阿司匹林上的CAD的病人的UGIB的发生是低的，但是伴有重要病态。与阿司匹林的延长使用，UGIB继续是为有风险因素并且特别在有消化性溃疡，UGIB在趋于在阿司匹林治疗以后早发生的历史的病人的那些的一个问题。

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