简介：Theadsorptionofproteinonnanoparticleswasstudiedbyusingdynamiclightscatteringtomeasurethehydrodynamicsizeofbothpureproteinandnanoparticlesadsorbedwithdifferentamountsofprotein.Thethicknessoftheadsorbedproteinlayerincreasesasproteinconcentration,butdecreasesastheinitialsizeofnanoparticles.Afterproperlyscalingthethicknesswiththeinitialdiameter,weareabletofitallexperimentaldatawithasinglemastercurve.Ourexperimentalresultssuggestthattheadsorbedproteinsformamonolayeronthenanoparticlesurfaceandtheadsorbedproteinmoleculesareattachedtotheparticlesurfaceatmanypointsthroughapossiblehydrogen-bonding.Ourresultsalsoindicatethatasproteinconcentrationincreases,theoverallshapeoftheadsorbedproteinmoleculecontinuouslychangesfromaflatlayerontheparticlesurfacetoastretchedcoilextendedintowater.Duringthechange,thehydrodynamicvolumeoftheadsorbedproteinincreaseslinearlywithproteinconcentration.

简介：　　INTRODUCTION　　Nanoparticles,fortheirsubcellularsize,havebeenaimportantcarrierinsomefields.Thesefieldsincludepharmacology,food,cosmetic,etc.Here,wefocusonpresentapplicationsofnanoparticlesindrugcarrierandgenecarrier.　　……

简介：Wereviewhow,startingfrompolymericnanoparticles,togenerateclustersoffractalmorphologyandtoexpandtheentirespaceandinterconnecttoformgels,througheitherBrownianmotionorintenseshearinducedaggregation.InthecaseofBrownianmotion-inducedgelation,specifictechniquesdevelopedtoobtainuniformstructureofgelsunderbothreaction-limitedanddiffusion-limitedclusteraggregationconditionshavebeendescribed.Inthecaseofintenseshear-inducedgelationasanewlydevelopedtechnique,ourfocusisonitsprinciple,theoreticaldevelopmentandadvantageswithrespecttoBrownianmotion-inducedgelationinpracticalapplications.Weconsidergelationofbothrigidandsoftparticles.Asaphysicalprocess,thebondingbetweentheparticleswithingelsisowedtovanderWaalsattractions,thusbeingeasilybroken.However,inthecaseofsoftparticlesthatcancoalesceuponcontact,thecoalescencecanallowtheparticlestosticktogetherformingpermanentgels.Inthiscase,thegelstructurecanbecontrolledbycontrollingthedegreeofcoalescence.Techniquesusedtocontrolthedegreeofcoalescencehavealsobeendescribed.

简介：在用黄金和银做的塑造的nanoparticles的合成的进展在这篇文章被考察。这评论由分析在nanoparticle形状和它的内部水晶的结构的几何对称之间的关系以一个新角度开始。根据关系，有明确的形状的nanoparticles被分类进三个范畴：有单个crystallinity，有尖双胞胎的nanoparticles，和有平行双胞胎的nanoparticles的nanoparticles。为在每个范畴的塑造的nanoparticles的合成的古典方法的讨论和分析也被包括，在塑造的金属nanoparticles的合成的未来研究方向上的个人观点简短被总结。这评论被期望在为塑造的nanoparticles的合成设计策略并且分析相应生长机制提供一个指南。

简介：Polymer/metalcompositesegmentalJanusnanoparticles(NPs)aresynthesizedbysequentialgrowthagainstpoly(4-vinylpyridine)(P4VP)crosslinkedcP4VP-PSJanusNPs.AJanusclusterofpoly(4-vinylpyridine)-block-polystyrene(P4VPb-PS)diblockcopolymerisself-organizedafterabsorptionontoasilicapatchysphereviahydrogenbonding.SelectivecrosslinkingofP4VPleadstotheformationofrobustcP4VP-PSJanusNPs.WithinthecP4VPdomain,functionalspeciessuchasmetalsarepreferentiallygrownbyinsitureduction.Otherthiol-cappedpolymers,forexample,thiol-cappedpoly(Nisopropylacrylamide)(PNIPAM-SH),canbeconjugatedontotheoppositesidetoformpolymer/metaltriplesegmentalJanusNPs.ThehyperthermiaeffectofAuNPofPNIPAM-Au@cP4VP-PSbynearinfrared(NIR)irradiationcantriggerafasttransitionfromamphiphilictohydrophobicoftheJanusNPsatlowsurroundingtemperature.De-stabilizationoftheemulsionisNIRtriggeredalthoughthesystemtemperatureisbelowLCST(~32°C).

简介：spirooxazine(SPO)和它的photomerocyanine(PMC)的nanoparticles通过降水方法被准备。二个不同特征被观察。一个人是为PMCnanoparticles的腐烂的一生为驱散的分子是600次那，并且其它是SPOnanoparticles的荧光紧张到240次驱散的单体的被提高。

简介：Objective:Estimationofactivityaccumulatedintumorandorgansisveryimportantinpredictingtheresponseofradiopharmaceuticalstreatment.Inthisstudy,wesynthesized177Lutetium(177Lu)-trastuzumabironoxidenanoparticlesasadoubleradiopharmaceuticalagentfortreatmentandbetterestimationoforganactivityinanewwaybymagneticresonanceimaging（MRI）.Methods:177Lu-trastuzumab-ironoxidenanoparticlesweresynthesizedandallthequalitycontroltestssuchaslabelingyield,nanoparticlesizedetermination,stabilityinbufferandbloodserumupto4d,immunoreactivityandbiodistributioninnormalmiceweredetermined.Inmicebearingbreasttumor,liverandtumoractivitieswerecalculatedwiththreemethods:singlephotonemissioncomputedtomography（SPECT）,MRIandorganextraction,whichwerecomparedwitheachother.Results:Thegoodresultsofqualitycontroltests（labelingyield:61%±2%,meannanoparticlehydrodynamicsize:41±15nm,stabilityinbuffer:86%±5%,stabilityinbloodserum:80%±3%,immunoreactivity:80%±2%）indicatedthat177Lu-trastuzumab-ironoxidenanoparticlescouldbeusedasadoubleradiopharmaceuticalagentinmicebearingtumor.Resultsshowedthat177Lu-trastuzumab-ironoxidenanoparticleswithMRIhadtheabilitytomeasureorganactivitiesmoreaccuratethanSPECT.Conclusions:Co-conjugatingradiopharmaceuticaltoMRIcontrastagentssuchasironoxidenanoparticlesmaybeagoodwayforbetterdosimetryinnuclearmedicinetreatment.

简介：Thisresearchreportsthepreparationandcharacterizationofcoppernanoparticlesmodifiedbydidecylbenzenesulfonate(DBS),TheCunanoparticles'sizewasdeterminedtobe40nmbytransmissionelectronmicroscope(TEM).TheX-rayphotoelectronspectrometry(XPS)resultsshowthatthereareinteractionsbetweenthecoppernanoparticlesandDBSfunctiongroup.Thenonlinearopticalpropertieswerestudiedbythefour-wavemixingmethod.Thevalueofx^(3)/α0wasfoundtobe6.9×10^-11esucm.

简介：AnovelphotoelectrochemicalbiosensorincorporatingnanosizedCdSsemiconductorcrystalswithenzymetoenhancephotochemicalreactionhasbeeninvestigated.CdSnanoparticlesweresynthe-sizedbyusingdendrimerPAMAMasinnertemplates.TheCdSnanoparticlesandglucoseoxidase(GOD)wereimmobilizedonPtelectrodevialayer-by-layer(LbL)techniquetofabricateabiological-inorganichybridsystem.Underultravioletlight,thephoto-effectoftheCdSnanoparticlesshowedenhancementofthebiosensortodetectglucose.PtnanoparticlesweremixedintotheNafionfilmtoimmobilizetheCdS/enzymecompositesandtoimprovethechargetransferofthehybrid.Experimentalresultsdemon-stratethedesirablecharacteristicsofthisbiosensingsystem,e.g.asensitivityof1.83A/(mMcm2),lowerdetectionlimit(1M),andacceptablereproducibilityandstability.

简介：Polyvinylalcoholcoatedmagneticparticles（PVAferrofluids）havebeensynthesizedbychemicalco-precipitationofFe（Ⅱ）/Fe（Ⅲ）saltsin1.5mol/LNH4OHsolutionat70℃inthepresenceofPVA.Theresultantcolloidalparticleshavecore-shellstructures,inwhichtheironoxidecrystallitesformthecoresandPVAchainsformtheshells.Thehydrodynamicdiameterofthecolloidalparticlesisintherangeof108to155nm,whichincreaseswithincreasingPVAconcentrationfrom5wt%to20wt%.Thesizeofthemagneticcoresisca.5～10nm,whichisrelativelyindependentofPVAconcentration.Undertransmissionelectronmicroscopic（TEM）examination,themagneticcoresexhibitsomewhatirregularshapesvaryingfromspherical,oval,tocubic.MagnetometrymeasurementrevealedthatthePVAcoatedmagneticparticlesaresuperparamagnetic.Thesaturationmagnetizationof5wt%and20wt%PVAferrofluidsat300Kis54and49emu/g.respectively.AllthePVAferrofluidsexhibitedexcellentcolloidalstabilityinpurewaterandphosphatebuffersaline（PBS,pH=7.4）.Theferrofluidscanremainstableinabovesolutionsformorethanthreemonthsat4℃.

简介：Thispaperreviewsourworkonthefundamentalprinciplesofhighgravitycontrolledprecipitation(HGCP)technology,anditsapplicationsintheproductionofdrugnanoparticles,whichwascarriedoutinarotatingpackedbed(RPB).Severalkindsofdrugnanoparticleswithnarrowparticlesizedistributions(PSDs)weresuccessfullypreparedviaHGCP,includingthe300-nmCefuroximeAxetil(CFA)particles,200–400-nmcephradineparticles,500-nmsalbutamolsulfate(SS)particles(100nminwidth),and850-nmbeclomethasonedipropionate(BDP)particles,etc.Comparedtodrugsavailableinthecurrentmarket,allthedrugnanoparticlesproducedbyHGCPexhibitedadvantagesinbothformulationanddrugdelivery,thusimprovingthebioavailabilityofdrugs.HGCPisessentiallyaplatformtechnologyforthepreparationofpoorlywater-solubledrugnanoparticlesfororalandinjectiondelivery,andofinhalabledrugsforpulmonarydelivery.Consequently,HGCPofferspotentialapplicationsinthepharmaceuticalindustryduetoitscost-effectiveness,efficientprocessingandtheeaseofscaling-up.

简介：Incipientplasmonicbubbleformationisobservedaroundgoldnanopillarswithdifferentinter-nanopillarseparations.Theexperimentalmeasurementsandtheoreticalanalysisshowthatthenanobubbleformationisduetotheenhancedplasmonicresonanceratherthanfromthelaserheating.Inter-nanopillardistributionmayleadtothresholdfluencevariations.Thelifetimeofplasmonicbubblescanreachseveralminutes.Furthermore,boththeradiusandthegrowthrateoftheplasmonicnanobubbleincreaseastheinter-nanopillardistributiondecreases.Smaller-spacingdistributedarraysproducedlargerbubbles.Themaximumgrowthrateofthebubblescanbereachedatabout883.5×10-6m∕son1μmnanopillars,butitisonly56.9×10-6m∕son4μmnanopillars.

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简介：我们学习在在相对地控告的多价的像杆的counterions的一个答案嵌入的二相似控告的表面之间的相互作用。counterions坚硬地由二组成结合的点费用，每原子价Z。有增加表面费用密度或费用的原子价的静电的联合增加的力量。系统被采用一个前後一致的领域理论分析，它在不同近似以内对待counterions的短、长期的相互作用。我们发现在弱联合限制，相互作用仅仅是排斥的。在中间的联合政体，多价的像杆的counterions能调停在表面之间的吸引人的相互作用。为足够地长的杆，衔接贡献吸引人的相互作用。在强壮的联合限制，费用关联能在在控告的表面之间的短分离贡献吸引人的相互作用。二最小然后能出现在在表面之间的力量曲线。

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简介：Carbon-supportedPdnanoparticleswerepreparedbymicrowaveheating-glycolreductionmethod,andcharacterizedbyawidearrayofexperimentaltechniquesincludingX-raydiffractionspectroscopy(XRD)andtransmissionelectronmicroscopy(TEM).TheelectrooxidationbehaviorsofethanolonthePd/Celectrodeinalkalinemediawereinvestigatedusingcyclicvoltammetry(CV),chronoamperometry(CA),electrochemicalimpedancespectroscopy(EIS)andsinglecellperformancemethods.Pd/Celectrodeforethanoloxidationshowedhighelectro-catalyticactivityandlongtermstability.However,itisobservedthatthecurrentdensitydecreaseswiththeincreasingofthepotentialandnegativeimpedancepresentsinthepotentialfrom-0.1to0.1V.Thedecreasingcurrentdensityandthenegativeimpedancecouldbeduetotheadsorbedintermediatesspeciesthatinhibitedthefurtheroxidationofethanol.BasedonthechemicalreactionanalysisandEISspectra,equivalentcircuitsrelatingtovariouspotentialzoneshavebeenobtained.TheseresultsrevealthedynamicadsorptionofintermediatesspeciesonPdsurfaces.Significantly,itisclarifiedthattheadsorptionbehaviorbeginsfromthemaximumcatalysisofelectro-catalysisandendsintheformationofthepalladium(II)oxidelayerontheelectrodesurface.

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简介：Hematitenanoparticleswhichwerecoated,respectively,withsodiumdodecylebenzenesulphonate(DBS)andcetyltrimethylammoniumbromide(CTAB)weresynthesizedbyusingmicroemulsionmethodinthesystemofwater/toluene.Theparticlesizeandshapewerecharacterizedwithtransmissuonelectronmicroscopy(TEM).TheTEMresultsshowthatthenanoparticlestaketheshapeofshperewithdimeterof5.0nmand6.0nmformodifiedDBSandCTABrespectively.ThelocalatomicstructuresofthesenanoparticleswereprobedbyusingXAFStechnique.Fe-Kabsorptionspectrawerecollectedatbeamline4W1BofBSRF.ThelocalatomicstructureinDBScoatedhematitewasfoundtobesimilarwiththatinbulkhematiteexcepttheanharmonicityincreasing,butabout0.04AexpansionofFe-ObondlengthinCTAB-coatedhematite,Theinterface/surfaceatomicconfigurationwerecomparedanddiscussed.

简介：ToxicityofMgOandZnOnanoparticlesatconcentrationsof250,500or1000mg/LforCitrusmaximaseedlingswasinvestigatedtoevaluatethepotentialityoftheiruseasnano-fertilizers.UptakeandtranslocationofmetaloxidenanoparticlesandlipidperoxidationweremeasuredandcomparedwiththoseofplantsexposedtothehighestequivalentconcentrationsofMg2+andZn2+.MgOnanoparticlesweretranslocatedfromrootstoshoots,whiletranslocationofZnOnanoparticleswaslow.ExposuretoMg2+andMgOatallconcentrationsentailedseveretoxicityandstrongoxidativestress.ZnOnanoparticlesshowedonlymildtoxicity,whileZn2+causedleafveinchlorosisandstrongoxidativestresstoplantshoots.Inconclusion,thetoxicityofMgOnanoparticlestotheplantresultedfromthedissolvedMg2+concentration,whilethatofZnOnanoparticleswasnotcorrelatedwiththedissolvedZn2+concentration.OurfindingsaresignificantfordevelopmentandapplicationofMgOandZnOnanoparticlesasnano-fertilizersinagriculture.