简介:大音阶的第五音胶化旋转涂层在Pt/Ti/SiO2/Sisubstrate上准备的Pb(Zr0.4Ti0.6)O-3电影作为最高的电极与磅或Ru被用于铁电体电容器。为thePt/PZT/Pt和Ru/PZT/Pt铁电体电容器,尽管与一样的铁电体他,不同最高的电极材料招致PZT电容器的不同性质例如疲劳,漏,残余、浸透的极化,除了PZTfilm的类似的水晶取向。在(10)10交换周期以后,Ru/PZT/Pt和Pt/PZT/Ptcapacitors的残余的极化分别地减少到70%和84%。在(8)10交换周期以后,后者的漏水流密度在积极偏爱显然增加,与前者相比。为最高的电极的Differentmaterials在PZT/top电极接口带不同条件。在PZT/electrode接口和在到充电注射的PZT/electrode接口的电极材料的氧化物的影响的氧空缺集中的Theinfluence能作为最高的电极与磅或Ru解释PZT电容器的性质的差别。
简介:摘要目的总结纯红细胞再生障碍(PRCA)的继发因素、实验室特点、治疗方案及预后。方法本研究为多中心回顾性临床研究,纳入2010年6月1日至2019年6月1日初诊的18岁以上PRCA患者进行随访,并根据不同治疗方案与药物减量速度等进行疗效、生存的比较分析。结果共纳入67例PRCA患者,其中继发性PRCA占44.8%(30/67),最常见的基础疾病为胸腺瘤(10例)和T细胞大颗粒淋巴细胞白血病(6例)。PRCA患者总缓解率(ORR)为85.7%,3年总体生存(OS)率为(74.3±7.5)%。单用环孢素A治疗缓解率稍高于单用激素或环孢素A联合糖皮质激素[90.0%(36/40)对75.0%(12/16),P=0.147]。环孢素A治疗达完全缓解或部分缓解3~6个月后,每次减量25 mg/d,减量间隔≥1个月组中位无病生存时间长于减量间隔<1个月组[未达到对15(95% CI 7~23)个月,P<0.001]。有62.5%(10/16)患者复发后按初始治疗方案或增加剂量再次治疗仍有效。结论PRCA可发生于多种疾病,缓解率与生存率高,单用环孢素A治疗效果好,起效且稳定后需缓慢减量以降低复发率。
简介:ThemetaloxidesCuMnCeandCeYwashcoatsoncordieritewerepreparedusinganimpregnationmethod,andthenusedassupportfortheactivePtcomponenttopreparethePt/CuMnCeandPt/CeYmonolithiccatalystsforthedeepoxidationofVOCs.IncomparisonwiththePt/CeY,CuMnCe,andCeYmonolithiccatalysts,thePt/CuMnCemonolithiccatalystshowsanexcellentperformancefortoluene,ethylacetate,andn-hexaneoxidationandtheT90%islowto216,200and260℃,respectively.TheactivecomponentsPt/PtOandCuMnCeresultinabettersynergeticinteraction,whichpromotethecatalystreducibility,increasetheoxygenmobility,andenhancetheadsorptionandactivationoforganicmolecules.
简介:目的:基于影像组学方法,分析超声医学影像信息,评估影像组学方法预测原发性肝细胞癌(hepatocellularcarcinoma,HCC)中Ki-67表达的可行性。方法:回顾性分析133例经术后病理证实的HCC患者的灰阶超声图像,通过图像分割、提取图像中肿瘤病灶的小波、纹理、形态特征,结合最大相关最小冗余(minimum-redundancy-maximum-relevance,mRMR)准则的遗传算法选出234个特征,之后再用稀疏表示(sparserepresentationcoefficient,SRC)方法进一步筛选,得到最优特征子集并用于分类。结果:利用支持向量机(supportvectormachine,SVM)和留一法(leave-one-outcrossvalidation,LOOCV)的预测模型对临床HCC超声图像进行分类和评价。结果显示,受试者操作特性曲线下面积(areaunderthereceiveroperatingcharacteristiccurve,AUC)达到了0.75。结论:基于HCC超声灰阶图像的影像组学分析和Ki-67表达存在相关性,可以为临床合理诊疗和预后预测提供有用的信息。
简介:摘要目的研究血管内皮生长因子(VEGF)和Ki-67在口腔鳞状细胞癌(OSCC)中的表达及意义。方法采用免疫组织化学EnVision法检测30例OSCC和20例正常口腔粘膜(NOM)中VEGF和Ki-67的表达情况。结果VEGF和Ki-67在OSCC中的表达阳性率明显高于NOM,差异具有统计学意义(P<0.05);VEGF和Ki-67阳性表达与病理组织学分级和淋巴结转移呈正相关(P<0.05),与OSCC患者的年龄和性别无关(P>0.05);同时表达与组织分化和淋巴结转移相比较均有显著性差异(P<0.05)。结论VEGF和Ki-67在OSCC中高表达,两者可能与口腔鳞状细胞癌的发生、发展、侵袭及转移有关。
简介:Electrolysisofammoniainalkalineelectrolytesolutionwasappliedfortheproductionofhydrogen.BothPt-loadedNifoamandPt-IrloadedNifoamelectrodeswerepreparedbyelectrodepositionandservedasanodeandcathodeinammoniaelectrolyticcell,respectively.TheelectrochemicalbehaviorsofammoniainKOHsolutionwereindividuallyinvestigatedviacyclicvoltammetryonthreeelectrodes,i.e.bareNifoamelectrode,Pt-loadedNifoamelectrodeandPt-IrloadedNifoamelectrode.ThemorphologyandcompositionofthepreparedNifoamelectrodewereanalyzedbyscanningelectronmicroscopy(SEM)andX-raydiffraction(XRD).Effectsoftheconcentrationofelectrolytesolutionandtemperatureofelectrolyticcellontheelectrolysisreactionwereexaminedinordertoenhancetheefficiencyofammoniaelectrolysis.Thecompetitionofammoniaelectrolysisandwaterelectrolysisinthesamealkalinesolutionwasfirstlyproposedtoexplainthechangesofcellvoltagewiththeelectrolysisproceeding.Atvaryingcurrentdensities,differentcellvoltagescouldbeobtainedfromgalvanostaticcurves.Thelowcellvoltageof0.58V,whichislessthanthepracticalelectrolysisvoltageofwater(1.6V),canbeobtainedatacurrentdensityof2.5mA/cm2.Basedonsomeexperimentalparameters,suchastheappliedcurrent,theresultingcellvoltageandoutputofhydrogengas,thepowerconsumptionpergramofH2producedcanbeestimated.
简介:Thisworkreportsafeasiblesynthesisofhighly-dispersedPtandPt-Fenanoparticlessupportedonmultiwallcarbonnanotubes(MWCNTs)withoutFeandmultiwallcarbonnanotubeswithiron(MWCNTs-Fe)whichappliedaselectrocatalystsformethanolelectrooxidation.APtcoordinationcomplexsaltwassynthesizedinanaqueoussolutionanditwasusedasprecursortopreparePt/MWCNTs,Pt/MWCNTs-Fe,andPt-Fe/MWCNTsusingFeCl24H2OasironsourcewhichwerenamedS1,S2andS3,respectively.Thecoordinationcomplexofplatinum(TOA)2PtCl6wasobtainedbythechemicalreactionbetween(NH4)2PtCl6withtetraoctylammoniumbromide(TOAB)anditwascharacterizedbyFT-IRandTGA.ThematerialswerecharacterizedbyRamanspectroscopy,SEM,EDS,XRD,TEMandTGA.TheelectrocatalyticactivityofPt-basedsupportedonMWCNTsinthemethanoloxidationwasinvestigatedbycyclicvoltammetry(CV)andchronoamperometry(CA).Pt-Fe/MWCNTselectrocatalystsshowedthehighestelectrocatalyticactivityandstabilityamongthetestedelectrocatalystsduetothattheadditionof'Fe'promotestheOHspeciesadsorptionontheelectrocatalystsurfaceatlowpotentials,thus,enhancingtheactivitytowardthemethanoloxidationreaction(MOR).
简介:TheeffectofPtandCuelectrodesontheresistiveswitchingpropertiesandfailurebehaviorsofamorphousZrO2?lmswereinvestigated.ComparedwithCu/ZrO2/Ptstructures,thePt/ZrO2/PtstructuresexhibitbetterresistiveswitchingpropertiessuchasthehigherresistanceratioofOFF/ONstates,thelongerswitchingcyclesandnarrowdistributionofOFFstateresistance(Roff).TheswitchingmechanisminthePt/ZrO2/Ptstructurecanbeattributedtotheformationandruptureofoxygenvacancy?laments;whileintheCu/ZrO2/Ptstructure,thereexistbothoxygenvacancy?lamentsandCu?laments.TheformationofCu?lamentsisrelatedtotheredoxreactionofCuelectrodeundertheappliedvoltage.TheinhomogeneousdispersiveinjectionofCuionsresultsinthedispersiveRoffandsigni?cantdecreaseofoperatevoltage.Schematicdiagramsoftheformationofconductive?lamentsandthefailuremechanismintheCu/ZrO2/Ptstructuresarealsoproposed.