简介:Thenegativeionfastatombombardment(NIFAB)massspectraofmono-,di-saccharidesandglycosidesusingphenylboronicacid(PBA)asreagenthavebeenstudied.Intheionsource,PBAreactsstereospecificallywiththemoleculescontainingcis-vicinalglycolstoformcharacteristicions,fromwhichthestereo-isomersofsaccharidescanbedefinitelydistinguished.Disaccharidesandglyco-sideswithβ-glycosidiclinkageseemtobeunfavorabaletoreactwithPBA,therefore,bycomparisonoftheabundancesofthecharacteristicions,theconfigurationoftheglycosidiclinkageinthesecompoundsmaybeinferred.