简介：无

简介：BackgroundTwo-dimensionalspeckletrackingimaging(2D-STI)andreal-timethree-dimensionalechocardiography(RT-3DE)havemoreadvantagesinevaluatingleftventricular(LV)systolicdyssynchronythantraditionalechocardiographictechniques.ThestudyaimedtoevaluateLVdyssynchronyparametersbyboth2D-STIandRT-3DE,andthecorrelationbetweenthesetwotechniques.MethodsAtotalof43chronicheartfailure(CHF)patientsand27healthyvolunteerswereenrolled.Therewere23dyssynchronyparametersselectedtoevaluateleftventricularsystolicsynchronization,involving15from2D-STIand8fromRT-3DE.ResultsFewofthedyssynchronyparametersshowednegativecorrelationswithLVejectionfraction(LVEF)intheCHFgroup.Thedifferencebetweentimetopeak-systolicradialstrainoftheanteroseptalandposteriorsegmentsatthelevelofpapillarymuscles[AS-P(RS)]from2D-STIshowedpositivecorrelationswithpartsoftheparametersfromRT-3DE(P<0.05).ConclusionsLVsystolicdysfunctiondoesnotcorrelatewithdyssynchrony.Moreover,thereisaweakassociationbetween2D-STIandRT-3DEinassessmentofleftventriculardyssynchrony.

简介：AbstractBackground:Hemifacial microsomia (HFM), which involves multiple sites with different levels of severity, is the second most common congenital craniofacial deformity after cleft lip and palate. However, three-dimensional (3D) measurements of mandibular deformities have not yet been studied in detail. The objective of this study is to investigate the method of 3D measurements of mandibular deformities in HFM patients.Methods:A total of 48 HFM patients were included in this study. All clinical treatment for patients was performed in the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences at Peking Union Medical College from June 2006 to June 2020. The patients’ 3D computerized tomography scan data were processed using medical imaging software, following four iterative steps: 3D reconstruction, mirroring, differential analysis, and partition.Results:The characteristics of the mandibular bone in HFM patients are mainly presented as follows: (1) compared to the normal side, the part of the bone body that extends from the ascending ramus to the pogonion (Po-NB) is analyzed using a dynamic process: less fullness-fullness-more fullness; (2) absences were frequently observed among the angular zones, that is, the height of the ascending ramus is deficient.Conclusions:HFM is a complicated condition with numerous variations in clinical presentation. We employed both 3D image reconstruction and computerization image processing techniques to investigate asymmetrical mandibular deformity in HFM patients in detail and with great accuracy. This will be of great use to clinicians for disease management.

简介：无

简介：AbstractPurpose:Secondary displacement represents a frequent complication of conservative treatment of fractures, particularly of the distal radius. The gap space between skin and cast may lead to a certain degree movements and this increased mobility might favor redisplacement. The aim of this study was to develop a new 3D method, to measure the gap space in all 3 geometrical planes, and to validate this new technique in a clinical setting of distal radius fractures.Methods:This study applies 3D imaging to measure the space between plaster and skin as a potential factor of secondary displacement and therefore the failure of conservative treatment. We developed and validated a new methodology to analyze and compare different forearm casts made of plaster of Paris and fiberglass. An unpaired t-test was performed to document differences between the investigated parameters between plaster of Paris and fiberglass casts. The significance level was set at p< 0.05.Results:In a series of 15 cases, we found the width of the gap space to average 4 mm, being slightly inferior on the radial side. Comparing the two different casting materials, plaster of Paris and fiberglass, we found a significantly larger variance of space under casts made of the first material (p=0.39). A roughness analysis showed also a markedly significantly higher irregularity of the undersurface of plaster of Paris as compared with fiberglass.Conclusion:This study allows for a better understanding of the nature of the "gap space" between cast and skin and will contribute to develop and improve new immobilization techniques and materials.

简介：Three-dimensional(3D)printing(3DP)isarapidprototypingtechnologythathasgainedincreasingrecognitioninmanydifferentfields.Inherentaccuracyandlow-costpropertyenableapplicabilityof3DPinmanyareas,suchasmanufacturing,aerospace,medical,andindustrialdesign.Recently,3DPhasgainedconsiderableattentioninthemedicalfield.Theimagedatacanbequicklyturnedintophysicalobjectsbyusing3DPtechnology.Theseobjectsarebeingusedacrossavarietyofsurgicalspecialties.Theshortageofcadaverspecimensisamajorprobleminmedicaleducation.However,thisconcernhasbeensolvedwiththeemergenceof3DPmodel.Custom-madeitemscanbeproducedbyusing3DPtechnology.Thisinnovationallows3DPuseinpreoperativeplanningandsurgicaltraining.Learningisdifficultamongmedicalstudentsbecauseofthecomplexanatomicalstructuresoftheliver.Thus,3Dvisualizationisausefultoolinanatomyteachingandhepaticsurgicaltraining.However,conventionalmodelsdonotcapturehapticqualities.3DPcanproducehighlyaccurateandcomplexphysicalmodels.Manytypesofhumanoranimaldifferentiatedcellscanbeprintedsuccessfullywiththedevelopmentof3Dbio-printingtechnology.Thisprogressrepresentsavaluablebreakthroughthatexhibitsmanypotentialuses,suchasresearchondrugmetabolismorliverdiseasemechanism.Thistechnologycanalsobeusedtosolveshortageoforgansfortransplantinthefuture.

简介：无

简介：瞄准：为了检验因素，用一个最近确定的在试管内模型在肠的巨噬细胞(IMAC)的区别包含了。方法：测试是否可溶或膜界限因素induceIMAC区别，刚，elutriated单核白血球(瞬间)与肠的上皮细胞(IEC)的调节媒介或细胞膜被孵化或与在transwell系统的IEC有教养。决定瞬间的活跃迁居的重要性，从瞬间和IEC的1:1混合的三维的总数被免疫组织化学和流动血细胞计数检验。Apoptosis被caspase-3检验西方的污点。在区别模型的细胞外的矩阵生产被免疫组织化学比较。结果：IMAC区别在一个复杂三维的合作文化模型被观察(多细胞的球状体，MCS)与在进球状体的瞬间的移植以后的IEC。由有调节媒介或IEC的膜准备的瞬间的合作文化，没有IMAC区别被导致。有在transwell文化的IEC的瞬间的合作文化，与二个房间，膜也分开的人口没导致瞬间的象肠一样区别。与有在IEC和瞬间的混合MCS入境瞬间的IEC球状体相对照，瞬间的一张仅仅小潜水艇人口能熬过七个天文化时期。结论：瞬间在试管内的象肠一样区别仅仅在三维的MCS在在IMAC的区别期间显示房间矩阵或房间房间相互作用的一个角色的瞬间的移民以后建模的建筑群被导致。

简介：

简介：客观：调查运动人工制品的影响在上三维(3D)重建体积和保角的放射疗法计划。方法：能沿着头部尾的方向模仿肺肿瘤的片断运动的一个幽灵被步进马达构造，聚乙烯和土豆的小球。十个不同扫描协议被设置，幽灵的CT数据被使用一台商业GELightSpeed16CT扫描仪获得。CT数据的3D重建被采用GEAdvantageSim6.0系统的显示卷的技术实现。在不同扫描协议的每个目标的重建的体积通过测量工具的3D被测量。因此，在动人的目标和静态的之间的重建体积的相对偏差是坚定的。三维的保角的放射治疗(3DCRT)计划和保角的地与计划系统(TPS)的WiMRT处理为一个静态/动人的目标被创造并且比较。结果:为一个静态的目标，当CT数据与不同程度和片被获得时，在3D重建卷之中没有明显的差别。3D重建体积和3D的外观一个动人的目标的保角的地与静态的的相当不同。最大的相对偏差为与不同扫描协议扫描的一个动人的目标是将近90%。相对偏差在不同目标之中是可变的，关于从-39.8%到89.5%为一个更小的目标并且从-18.4%到20.5%为更大的one.Conclusion:运动人工制品在3D-CRT计划和重建体积上有大效果，它将极大地为一个动人的目标导致弄歪的保角的放射域和假DVH。

简介：瞄准：讨论CT的临床的价值三维(3-D)在诊断胃肠道疾病的成像。方法：52个病人的Three-D成像调查结果回顾地被分析。Three-D成像方法包括的遮的表面显示(SSD)，显示的体积(VR)，虚拟内视镜检查法(VE)(MPR)并且多平面的重新格式化。CT3-D的诊断结果被比较内视镜检查法或外科的发现与那些评估。结果：有胃肠道疾病的52个病人被CT3-D成像，50个盒子正确地被诊断诊断，2被误诊。有胃的疾病的33个盒子(27与癌，5与消化性溃疡并且1与平滑肌瘤)并且19大肠的疾病(10与结肠癌，2与直肠的癌，5与结肠息肉并且2与回盲肠连接的肺结核)。有突出的损害的22个盒子(9与随后的空损害)，20与洞的狭窄(8与伴随物突出的损害)并且10与空损害(5与伴随物突出的损害)在3-D图象被显示出。显示出的最小的损害是1.0厘米x0.8厘米x0.5厘米。结论：CT3-D成像，没有疼痛的非侵略的考试，能清楚地并且直接与精确地点和高诊断精确性显示胃肠道的损害。它是到内视镜检查法的一种重要互补技术。

简介：AIMTodescribeathree-dimensionalmodel（3DM）toaccuratelyreconstructanatomicrelationshipsofcentrallylocatedhepatocellularcarcinomas（HCCs）.METHODS：FromMarch2013toJuly2014,reconstructionsandvisualsimulationsofcentrallylocatedHCCswereperformedin39patientsusinga3Dsubject-basedcomputedtomography（CT）modelwithcustomdevelopedsoftware.CTimageswereusedforthe3DreconstructionofCouinaud＇spediclesandhepaticveins,andthecalculationofcorrespondingtumorterritoriesandhepaticsegmentswasperformedusingYorktalDMITsoftware.Therespectivevolume,surgicalmargin,andsimulatedvirtualresectionoftumorswerealsoestimatedbythismodelpreoperatively.Allpatientsweretreatedsurgicallyandtheresultswereretrospectivelyassessed.Clinicalcharacteristics,imagingdata,procedurevariables,pathologicfeatures,andpostoperativedatawererecordedandcomparedtodeterminethereliabilityofthemodel.RESULTS：3Dreconstructionallowedstereoscopicidentificationofthespatialrelationshipsbetweenphysiologicandpathologicstructures,andofferedquantifiableliverresectionproposalsbasedonindividualizedliveranatomy.Thepredictedvalueswereconsistentwiththeactualvaluesfortumormassvolume（82.4±109.1mLvs84.1±108.9mL,P=0.910）,surgicalmargin（10.1±6.2mmvs9.1±5.9mm,P=0.488）,andmaximumtumordiameterthenumberandextentofportalvenousramifications,aswellastheirrelationtohepaticveins,werevisualized.Preoperativeplanningbasedonsimulatedresectionfacilitatedcompleteresectionoflargetumorslocatedintheconfluenceofmajorvessels.Andmostofthepredicteddatawerecorrelatedwithintraoperativefindings.CONCLUSION：This3DMprovidesquantitativemorphometryoftumormassesandastereo-relationshipwithadjacentstructures,thusprovidingapromisingtechniqueforthemanagementofcentrallylocatedHCCs.

简介：

简介：Reasonabledenturedesignwillaffectthehealthoforalsupportingtissueandrelatetothesuccessandfailureofprosthodontic.Inordertoinvestigatethestressdistributeoforalsupportingtissueswiththreevariousdesignsunderconditionsofverticalloading,wemeasuredthemodelofthelossoflowerfirstmolarwith3-Dco-ordinatemeasuringapparatus,anddidanaloguedenturedesignwithauto-CADsoft-waresystemincomputer.AllmodelswereanalyzedwithSuper-SAPfiniteelementprogram.Ineachcase,150Nverticalloadingwasappliedonthesecondpremolar,

简介：AbstractBackground:Fetal weight is an important parameter to ensure maternal and child safety. The purpose of this study was to use three-dimensional (3D) limb volume ultrasound combined with fetal abdominal circumference (AC) measurement to establish a model to predict fetal weight and evaluate its efficiency.Methods:A total of 211 participants with single pregnancy (28-42 weeks) were selected between September 2017 and December 2018 in the Beijing Obstetrics and Gynecology Hospital of Capital Medical University. The upper arm (AVol)/thigh volume (TVol) of fetuses was measured by the 3D limb volume technique. Fetal AC was measured by two-dimensional ultrasound. Nine cases were excluded due to incomplete information or the interval between examination and delivery >7 days. The enrolled 202 participants were divided into a model group (134 cases, 70%) and a verification group (68 cases, 30%) by mechanical sampling method. The linear relationship between limb volume and fetal weight was evaluated using Pearson Chi-squared test. The prediction model formula was established by multivariate regression with data from the model group. Accuracy of the model formula was evaluated with verification group data and compared with traditional formulas (Hadlock, Lee2009, and INTERGROWTH-21st) by paired t-test and residual analysis. Receiver operating characteristic curves were generated to predict macrosomia.Results:AC, AVol, and TVol were linearly related to fetal weight. Pearson correlation coefficient was 0.866, 0.862, and 0.910, respectively. The prediction model based on AVol/TVol and AC was established as follows: Y=-481.965+ 12.194TVol + 15.358AVol + 67.998AC, R2adj = 0.868. The scatter plot showed that when birth weight fluctuated by 5% (i.e., 95% to 105%), the difference between the predicted fetal weight by the model and the actual weight was small. A paired t-test showed that there was no significant difference between the predicted fetal weight and the actual birth weight (t= -1.015, P = 0.314). Moreover, the residual analysis showed that the model formula’s prediction efficiency was better than the traditional formulas with a mean residual of 35,360.170. The combined model of AVol/TVol and AC was superior to the Lee2009 and INTERGROWTH-21st formulas in the diagnosis of macrosomia. Its predictive sensitivity and specificity were 87.5% and 91.7%, respectively.Conclusion:Fetal weight prediction model established by semi-automatic 3D limb volume combined with AC is of high accuracy, sensitivity, and specificity. The prediction model formula shows higher predictive efficiency, especially for the diagnosis of macrosomia.Trial Registration:ClinicalTrials.gov, NCT03002246; https://clinicaltrials.gov/ct2/show/NCT03002246?recrs=e&cond=fetal& draw=8&rank=67.

简介：

简介：

简介：Havingawiderangeofmotion,thecervicalspineisratherpredisposedtotrau-maandotherdisorderswithseriousconsequences.Themotionofcervicalspineisacomplexonecomposedofmicromotions,includinghorizontaldisplacementsalongallthreeaxesandrotationsaroundthemwithsixfreedomdegreesofmovement.Reportonprecisemeasurementofthethree-dimensionalmotionofthecervicalsectionof

简介：AbstractBackground:Extra-corporeal video telescope operating monitor system provides a necessary instrument to perform high-precision neurosurgical procedures that could substitute or supplement the traditional surgical microscope. The present study was designed to evaluate a compact high-definition two-dimensional exoscope system for assisting in surgical removal of large vestibular schwannoma (VS), as an alternative to a binocular surgical microscope.Methods:Patients with Koos grade 3 and grade 4 VS undergoing surgery were enrolled in this prospective cohort study between January 2013 and June 2018. The demographics and tumor characteristics (size, Koos grade, composition [cystic or solid mass]) were matched between the two groups of patients. The following outcome measurements were compared between the two groups: duration of surgery, volume of blood loss, extent of tumor resection, number of operating field adjustments, pre- and post-operative facial and cochlear nerve function evaluated at 3 months post-surgery, complications and surgeons’ comfortability.Results:A total of 81 patients received tumor resection through the retrosigmoid approach under either an exoscope (cases, n = 39) or a surgical microscope (control, n = 42). Patients in the two groups had comparable tumor location (P = 0.439), Koos grading (P = 0.867), and composition (P = 0.891). While no significant differences in the duration of surgery (P = 0.172), extent of tumor resection (P = 0.858), facial function (P = 0.838), and hearing ability (P = 1.000), patients operated on under an exoscope had less blood loss (P = 0.036) and a fewer field adjustments (P < 0.001). Both primary and assistant surgeons reported a high level of comfort operating under the exoscope (P = 0.001 and P < 0.001, respectively).Conclusions:The compact high-definition two-dimensional exoscope system provides a safe and efficient means to assist in removing large VSs, as compared to a surgical microscope. After the acquaintance with a visual perception through a dynamic hint and stereoscopically viewing corresponding to the motion parallax, the exoscope system provided a comfortable, high-resolution visualization without compromising operational efficiency and patient safety.

简介：