摘要
AIMTodescribeathree-dimensionalmodel（3DM）toaccuratelyreconstructanatomicrelationshipsofcentrallylocatedhepatocellularcarcinomas（HCCs）.METHODS：FromMarch2013toJuly2014,reconstructionsandvisualsimulationsofcentrallylocatedHCCswereperformedin39patientsusinga3Dsubject-basedcomputedtomography（CT）modelwithcustomdevelopedsoftware.CTimageswereusedforthe3DreconstructionofCouinaud＇spediclesandhepaticveins,andthecalculationofcorrespondingtumorterritoriesandhepaticsegmentswasperformedusingYorktalDMITsoftware.Therespectivevolume,surgicalmargin,andsimulatedvirtualresectionoftumorswerealsoestimatedbythismodelpreoperatively.Allpatientsweretreatedsurgicallyandtheresultswereretrospectivelyassessed.Clinicalcharacteristics,imagingdata,procedurevariables,pathologicfeatures,andpostoperativedatawererecordedandcomparedtodeterminethereliabilityofthemodel.RESULTS：3Dreconstructionallowedstereoscopicidentificationofthespatialrelationshipsbetweenphysiologicandpathologicstructures,andofferedquantifiableliverresectionproposalsbasedonindividualizedliveranatomy.Thepredictedvalueswereconsistentwiththeactualvaluesfortumormassvolume（82.4±109.1mLvs84.1±108.9mL,P=0.910）,surgicalmargin（10.1±6.2mmvs9.1±5.9mm,P=0.488）,andmaximumtumordiameterthenumberandextentofportalvenousramifications,aswellastheirrelationtohepaticveins,werevisualized.Preoperativeplanningbasedonsimulatedresectionfacilitatedcompleteresectionoflargetumorslocatedintheconfluenceofmajorvessels.Andmostofthepredicteddatawerecorrelatedwithintraoperativefindings.CONCLUSION：This3DMprovidesquantitativemorphometryoftumormassesandastereo-relationshipwithadjacentstructures,thusprovidingapromisingtechniqueforthemanagementofcentrallylocatedHCCs.
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
