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简介：Theflowaroundtwoplateshavingasymmetricbeveledtrailingedgeplacedside-by-sideinauniformstreamwereinvestigatedbothnumericallyandexperimentally.Twoplateswithspacingratioof1.0andbeveledtrailingedgeofangle20oweretestedatReynoldsnumbersequalto3.97×104.Thenumericalsimulationresultsdisplayedthattheflowseparatesononeplatebeveledtrailingedgesurface.Thevortexformationandsheddingfromthisplateledtodeflectingtheflowtowardtheotherplateandconsequentlythewakebehindtheplatesshowedanasymmetricdevelopment.Thephotographsobtainedfromtheflowvisualizationconfirmedthenumericalresultsconcerningtheflowseparationandvortexformation.Itwasalsofoundthatthecomputedpressuredistributiononthetwoplatesurfaceswasdifferent,particularlyonthebeveledtrailingedgesurfacesandontheflatsides.

简介：Themomentumequationforsolid-liquidtwo-phaseflowproposedbyElghobashiandAbou-Arabistakenasthegoverningequationsfortheliquidphase,andtheLagrangiandynamicequationforasphericalparticlemovingintheliquidflowasthebasicequationfortherelativemotionoftheparticleintheliquidphaseinthepaper.Thedynamicsequationforabubbleinsolid-liquidtwophaseflowisproposed,aswellasthesimplifiedequationsundertwoextremeconditionswiththerelationshipbetweenthebubblecollapsecharacteristictimeτC*andparticleresponsetimeτrel*beingτC*>>τrel*andτC*<<τrel*.

简介：Thewaterintakeheadinstalledwithinclinedboardingsiscalledlaminatesedimentprecipitation,whichseparatesliquidandsolidparticlesintwo-phaseflowbygravity.ThepaperpresentstheequationsforcalculatingthedistanceHbetweentwoincllinedboardings,indicatingthatHhasakeyeffectontheparticleprecipitationvelocityV2.Thepaperfocusesalsoonthecal-culationofhydraulicsimilarityofmodelwiththetheoreticmodel.

简介：Thisworkaimstoinvestigatetheeffectsofdosingregimentsondrugdeliveryinsolidtumorsandtovalidatethemwithexperimentsonrats.Thelumpedparametermodelsofpharmacokineticsandofdrugdeliveryintumorweredevelopedtosimulatetimecoursesofaveragedrugconcentration(Ct)oftumorinterstitiumintwotypesofdosingregiments(i.e.,single-shotandtriple-shotones).Thetworegimentswereperformedviaantitumordrug,hydroxycamptothecin(HCPT),onrats,tomeasurethedrugconcentrationinthetumor.Thesimulationsofthedrugconcentrationinthetumorofthetwodosingregimentswereconductedandcomparedwiththeexperimentaldataonrats.Thecoefficientsinthemodelswereinvestigated.Itisconcludedthatthetriple-shotmethodismoreeffectivethanthatofsingle-shotinjection.Thepresentlumped-parametermodelisquantitativelycompetentfordrugdeliveryinsolidtumor.

简介：Duringthedevelopmentoflowpermeabilityreservoirs.theinteractionbetweenfluidflowandrock-massdeformationisobvious.Onthebasisoffluidmechanicsinporousmediaandelasto-plastictheory.theauthorpresentsanequivalentcontinuummodeltosimulatefluidflowinfracturedlow-permeabilityoilreservoircoupledwithgeo-stress.Themodelnotonlyreflectstheporositychangeofmatrix,butalsothepermeabilitychangeduetotheopeningandclosingoffracture.Byanalyzingofsimulationresults,thechangesinporosityandpermeabilityandtheireffectonoildevelopmentarestudied.