简介：以便阐明，并且阻止病毒的疾病发生在橄榄疾病的状态，特别病毒的疾病挣扎育种站，包括流行病学的学习，研究的一个范围从1997～2003被执行。调查的育种站的地点在东方包括几个代表性的地点(Kangnung，Uljin，Pohang，Yangsan，Ul圣，釜山)，南方(Wando，Changheung，Goheung，Yeosu，Namhae，Tongyeong，Geoje，Jeju)并且西方(Seosan，Kunsan，Gochang，Yeongkwang，Mokpo，Chindo)朝鲜半岛的肋骨的区域。A总数of2000案例在7年，死亡由病毒的代理人报道for22%，或446个案例在引起了里被检验了。更加与病毒的感染联系的死亡在2003从14%in1997增加了到27%。许多病毒的疾病被观察，并且病毒的表皮的增生，病毒的腹水和病毒的畸形，病毒的紧张的坏死，和hiramerhabdoviral疾病的出现分别地是14%，51%，25%，和8%。由调查病毒的感染ofbroodstock挣扎，在育种站的海洋的birnavirus(MABV)的感染率被识别因此，是约30%获得并且使窝雪鱼干非感染是高度必要的。

简介：Oysterextractisaneffectivebioactivitycomponent.Ithasabundantnutritionalvalueandantiviral,antitumorandimmunedefensefunctions.Theroleofoysterextractintreatingliverinjuryhasbeenpaidmoreattention.WeuseWistarratstomakealcoholicliverdiseasemodelthroughinjectingalcoholintorats'stomachs.Theseratswererandomlydividedintofivegroups:modelgroup,controlgroup,low-dose,middle-doseandhigh-doseexperimentalgroupwithadoseof0.12gkg-1,0.40gkg-1,and1.20gkg-1alcoholic.Afternineweeks,serumbiomarkers(ALT,AST,TGandTCHO),malondialdehyde(MDA),glutathione(GSH),C3a,C5a,IL-17,TNF-ɑ,anti-MAA-HASIgG,CD3+,CD4+,CD8+,NKcellactivationandzinccontentwereassessed.Theresultsshowedthattheserumbiomarkers(ALT,AST,TGandTCHO),MDAcontent,anti-MAA-HSAIgG,serumC3a,C5aIL-17andTNF-ɑlevelsofoysterextracttreatmentgroupsweresignificantlydecreasedincomparisonwithmodelgroup.Onthecontrary,GSHshowedadversetrend.SerumCD3+,CD4+andNKcellactivationweresignificantlyincreasedinmiddle-dosegroupandhigh-dosegroupcomparedwithmodelgroup,andtherewasdecreaseofCD8+activityinhigh-dosegroup.PlasmaZnlevelwasdecreasedinmodelgroupcomparedwiththatincontrolgroup.Meanwhile,MeanplasmaZnlevelsincreaseddramaticallyfollowingthedoseincreaseofagivenoysterextract.