简介：在这研究，我们比较了由我们与慢可编程的结冰的快速的结冰的内部方法人的精子结冰/融化重复的效果。从11个normozoospermic题目的精子样品通过密度坡度被处理并且把aliquots划分了成三：非结冰，快速的结冰并且慢可编程的结冰。在快速的结冰组的精子活动性和生存能力最好在慢结冰比那些组织(P<；0.01)在结冰/融化的第一，第二和第三个周期以后，但是在形态学没有差别。在第二个实验，快速的结冰在20个题目被重复三次。从每个融化的周期的样品用碱的彗星试金为DNA破碎被评估。DNA破碎开始在结冰/融化的第二个周期以后更加增加了。在第三个实验，快速的结冰在10个题目反复被做，直到没有能动精子在融化以后被观察。结冰/融化那个产出的不能动的精子重复的中部的数字是七(范围：5-8，意味着：6.8)。在结论，我们表明了那我们的快速的结冰方法给了更好的结果比的使用的处理精液结冰/融化重复标准慢可编程的结冰。这个方法能帮助在帮助繁殖技术最大化宝贵cryopreserved精子样品的用法。

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简介：在这篇文章下列随机拦截混合效果模型将被考虑：y_(ij)=v_i+x_(ij)~τβ+ε_(ij)，i=1，...，m；j=1,2，...，n_i，在此{v_i}arei.i.d。有吝啬的α和有限变化σ_v~2的随机的效果；{ε_(ij)}是有有限变化σ_ε~的i.i.d随机错误2。这里，我们将估计α，σ_v~2，σ_ε~2，β和学习他们的大样品性质例如强壮的一致性，强壮的集中率和asymptotic规度。

简介：Theone-waymultivariaterepeatedmeasurementsanalysisofvariance(1-wayMRMANOVA)modelforcompletedataandthesphericitytestarestudied.

简介：Anewquantitativeconceptisintroducedinthispaper,whichmaybeusedtofacilitatethemeasurementofthecontrollabilityofasubspace～subspacecontrollabilitydegree.Thentheconcreteformofthesubspacecontrollabilitydegreeofaflexiblestructureisderived,andtheerrorsofsubspacecontrollabilitydegreeanddynamicalresponsecausedbythesubstitutionofarepeatedmodesubspaceforacloselyspacedmodesubspacearediscussed.Alltheresultsshowthatthissubstitutionisrationalundersomeconditions.

简介：TheexcitingsourceoftheactivesourcerepeatedmonitoringislocatedintheXiliushuiReservoirinZhangye,GansuProvince.ThesystembeganoperatingnormallyonJuly9,2015,andwehadcompletedaperiodof40daysofcontinuousexcitationexperimentbeforeNovember10,2015.Ourresultsrevealthattheairgunsourcehasgoodconsistencyandrepeatability,andthedetectivesystemofactivesourcecanrecordsignalclearly.Theconstructionofactivesourcerepeatedexplorationprojectshasachievedsomeresults,whichcanprovidevaluableexperiencefortheresearchofactivesourcerepeatedexploration.TheobservationdataweobtainedmakesitpossibletofollowthetemporalandspatialvariationsofthedeepstructureoftheQilianMountainareas.

简介：Anewresponse-spectrummodesuperpositionmethod,entirelyinrealvalueform,isdevelopedtoanalyzethemaximumstructuralresponseunderearthquakegroundmotionforgenerallydampedlinearsystemswithrepeatedeigenvaluesanddefectiveeigenvectors.Thisalgorithmhasclearphysicalconceptsandissimilartothecomplexcompletequadraticcombination(CCQC)methodpreviouslyestablished.Sinceitcanconsidertheeffectofrepeatedeigenvalues,itiscalledtheCCQC-Rmethod,inwhichthecorrelationcoefficientsofhigh-ordermodalresponsesareenclosedinadditiontothecorrelationcoefficientsinthenormalCCQCmethod.Asaresult,theformulasforcalculatingthecorrelationcoefficientsofhigh-ordermodalresponsesarededucedinthisstudy,includingdisplacement,velocityandvelocity-displacementcorrelationcoefficients.Furthermore,therelationshipbetweenhigh-orderdisplacementandvelocitycovarianceisderivedtomaketheCCQC-Ralgorithmonlyrelevanttothehigh-orderdisplacementresponsespectrum.Finally,apracticalstep-by-stepintegrationprocedureforcalculatinghigh-orderdisplacementresponsespectrumisobtainedbychangingtheearthquakegroundmotioninput,whichisevaluatedbycomparingittothetheorysolutionunderthesine-waveinput.Themethodderivedhereissuitableforgenerallylinearsystemswithclassicalornon-classicaldamping.

简介：Arepeatedinterdiffusionmethodisdescribedforphase-stableandhigh-quality(FA,MA)PbI_3film.Thecrystallizationandgrowthoftheperovskitefilmscanbewellcontrolledbyadjustingthereactantconcentrations.Withthismethod,dense,smoothperovskitefilmswithlargecrystalshavebeenobtained.Finally,aPCEof16.5%aswellasasteady-stateefficiencyof16.3%isachievedintheplanarperovskitesolarcell.

简介：Inthisnoteasimpleiterativemethodforsimultaneouslyfindingallzerosofapolynomialisestablished.Themethoddoesnotrequirerepeatedevaluationofthepolynomialoritsderiva-tives,andisgloballyconvergentforquadraticpolynomials.

简介：AbstractObjective:The objective of this study is to study whether preimplantation genetic testing for aneuploidy (PGT-A) improves the clinical outcomes of infertile patients with repeated implantation failure (RIF) undergoing frozen-thawed embryo transfer.Methods:This is a retrospective analysis of clinical pregnancy, live birth, miscarriage rates, and obstetric and perinatal outcomes of women with RIF with or without PGT-A. Statistical analyses of categorical data were performed using propensity score matching (PSM), χ2 test, and Student’s t test.Results:We enrolled 466 patients with RIF, of which, 209 were in the RIF-PGT-A group. The rate of euploid blastocysts was significantly associated with age and day 5 or 6 blastocysts. There were significant differences between the RIF-PGT-A group and the RIF-non-PGT-A group across several parameters. After PSM, positive serum human chorionic gonadotropin (56.9% and 33.9%, P<0.01), clinical pregnancy (49.5% and 31.2%, P<0.01), live birth (43.1% and 25.7%, P<0.01), and fetal heart rates (50.0% and 29.8%, P<0.01) per transfer were significantly higher in the RIF-PGT-A group.Conclusion:Elective single-embryo transfer PGT-A can minimize the risk of obstetric and perinatal outcomes, especially fetal body weight, in women with RIF. Additionally, PGT-A can significantly improve pregnancy and live birth rates.

简介：Considerarepeatedmeasurementpartiallylinearregressionmodelwithanunknownvectorparameterβ,anunknownfunctiong(.),andunknownheteroscedasticerrorvariances.Inordertoimprovethesemiparametricgeneralizedleastsquaresestimator(SGLSE)ofβ,weproposeaniterativeweightedsemiparametricleastsquaresestimator(IWSLSE)andshowthatitimprovesupontheSGLSEintermsofasymptoticcovariancematrix.Anadaptiveprocedureisgiventodeterminethenumberofiterations.Wealsoshowthatwhenthenumberofreplicatesislessthanorequaltotwo,theIWSLSEcannotimproveupontheSGLSE.Theseresultsaregeneralizationsofthosein[2]tothecaseofsemiparametricregressions.

简介：应用根系喷雾箱（ＲｏｏｔＭｉｓｔｉｎｇＣｈａｍｂｅｒ，ＲＭＣ）形成的５次干旱循环，通过ＰＶ曲线的水分参数研究了多重复干旱循环对１年生北美短叶松ＰｉｎｕｓｂａｎｋｓｉａｎａＬａｍｂ．和黑云杉Ｐｉｃｅａｍａｒｉａｎａ［Ｍｉｌ］Ｂ．Ｓ．Ｄ．苗木耐旱特性的影响．结果表明，生长在干旱沙地的深根性树种北美短叶松，其丧失膨压的相对含水量（８０７６％～８１４１％）和水势（（－１７４±０１０）ＭＰａ）都比较低，细胞弹性模量（５７３～６５２ＭＰａ）比较小，而束缚水含量（５２７２％～５４２６％）比较高，显示出它固有的强有力的忍耐脱水能力；但是在多重复干旱循环下它却不能进一步调节其渗透势和细胞弹性，而且其束缚水含量和吸水能力也有所下降．生长在湿润地区的浅根性树种黑云杉，虽然其丧失膨压的相对含水量（８３５３％～８５５０％）和水势（（－１６８±００３）ＭＰａ）比较高，细胞弹性模量（８６２～９６４ＭＰａ）比较大，束缚水含量（３６４４％～４６０５％）比较低，显示出较弱的耐旱能力，但是它在多重复干旱循环下却能提高其束缚水含量以改善原生质耐旱程度，降低细胞弹性以提高其吸水能力，调节其渗透势以保持较高的膨压．这表?

简介：Objective:Toobservetheactivityofrepeatedextractsofbonematrixandtheproductionofpurifiedbonemorphogeneticproteins(BMPs).Methods:BMPswereextracted1-4timesfromfreshbovinecorticalbonebythemodifiedUrist'smethod,witheachcollectedprecipitateseparatedandlyophilizedaspartiallypurifiedBMPs.Anotherfreshbovinebonewasextractedthreetimesandtheprecipitatesweremixedandlyophilized.Meanwhile,thealkalinephosphatase(ALP)activitywasmeasuredbyaninvitroassayemployingculturedC2C12mousemyoblastcellsthroughtheosteoinductivityofbovineBMPsextractedfourtimesatdays1,4,7,and14,andthecorrelationbetweenBMPsquantitiesandcostingduringextractionprocesseswasanalyzed.Results:Thepurifiedandthecostshowedapositivecorrelation(r=0.969).ToseparateandlyophilizeeachcollectedprecipitateaspartiallypurifiedBMPsraisedthecost,andmixedprecipitatesalsocostmuch.ALPactivitiesof1standmixedextractionsofBMPswereshowntobehighlyosteoinductiveandkeepasignificantlyhighlevel(P<0.05-0.01)4daysafterculturingcomparedwiththe2nd,3rdand4thextractions,especiallythecontrolgroup.However,themoretimestheextractionwsdone,thelessactivityofBMPswasshownandmorecostingwas.Thex-rayandhistologicalanalysisalsoshowedthatthe1stextractionofBMPsinducedmoreossiclesandnewboneformation.Conclusions:TheresultsindicatedthatBMPsenhancedtheabilitiesofosteoinductiviytinC2C12cultureinvitro.ThefirstextractionofBMPsfromboneisfitfull,4thextractionsareunnecessaryfortheycostmoreandwastemoretime,saynothingofmixedextractions.

简介：ThedevastatingMS8.0WenchuanearthquakerupturedtwolargeparallelthrustfaultsalongthemiddlesegmentoftheLongmenshanthrustbelt.PreseismicandpostseismiclevelingdataindicatedthehangingwalloftheYingxiuBeichuan-NanbathrustfaultmainlypresentedcoseismicupliftwithrespecttothereferencepointatPingwucountytown,andtheobservedmaximumupliftof4.7mislocatedatBeichuancounty(Qushantown)whichisabout100mwestofthefaultscarp.ThefootwalloftheYingxiu-Beichuan-Nanbathrustfaultmainlyshowedsubsidencewithmaximumsubsidenceof0.6mneartherupture.Byemployingalistricdislocationmodel,wefoundthatthefaultgeometrymodelofexponentialdipangleδ=88°×[1-exp(-9/h)]withdepthof18kmanduniformthrust-slipof5.6mcouldfittheobservedcoseismicverticaldeformationverywell,whichverifiesthelistricthrustmodeloftheLongmenshanorogeniczone.

简介：TheeffectofrepeatedmeltingofthemotheringotonthethermalstabilityofaZr60All5Ni25glassyalloywasinvestigatedbydifferentialscanningcalorimetry(DSC).Experimentalresultsindicatethataftertherepeatedmeltingoftheingotsat1300and1580K,theglasstransitiontemperatureTgin.easesfrom686.4to690.7and696.8KandtheonsettemperatureofcrystallizationTxfrom757.9to758.6and763.4K,respectively,indicatingthatthethermalstabilitybecomeshigheraftertherepeatedarcmeltingofthemotheringotandthatitismoreeffectiveathighertemperature.Withintheframeworkofstructureheredity,theoriginoftheimprovementofthethermalstabilityofZr60AllsNi25bulkglassyalloyisdiscussed.

简介：AbstractBackground:The mechanism and characteristics of early and late drug-eluting stent in-stent restenosis (DES-ISR) have not been fully clarified. Whether there are different outcomes among those patients being irrespective of their repeated treatments remain a knowledge gap.Methods:A total of 250 patients who underwent initial stent implantation in our hospital, and then were readmitted to receive treatment for the reason of recurrent significant DES-ISR in 2016 were involved. The patients were categorized as early ISR (<12 months; E-ISR; n = 32) and late ISR (≥12 months; L-ISR; n = 218). Associations between patient characteristics and clinical performance, as well as clinical outcomes after a repeated percutaneous coronary intervention (PCI) were evaluated. Primary composite endpoint of major adverse cardiac events (MACEs) included cardiac death, non-fatal myocardial infarction (MI), or target lesion revascularization (TLR).Results:Most baseline characteristics are similar in both groups, except for the period of ISR, initial pre-procedure thrombolysis in myocardial infarction, and some serum biochemical indicators. The incidence of MACE (37.5% vs. 5.5%; P < 0.001) and TLR (37.5% vs. 5.0%; P < 0.001) is higher in the E-ISR group. After multivariate analysis, E-ISR (odds ratio [OR], 13.267; [95% CI 4.984-35.311]; P < 0.001) and left ventricular systolic dysfunction (odds ratio [OR], 6.317; [95% CI 1.145-34.843]; P = 0.034) are the independent predictors for MACE among DES-ISR patients in the mid-term follow-up of 12 months.Conclusions:Early ISR and left ventricular systolic dysfunction are associated with MACE during the mid-term follow-up period for DES-ISR patients. The results may benefit the risk stratification and secondary prevention for DES-ISR patients in clinical practice.