简介:AlkylatingagentsarechemicallyreactivedrugsthatreactwithDNAtoformcovalentbonds,causingsingle-strandordouble-strandDNAbreaksthatleadtointerstrandandintrastrandDNAcross-linking.Theseagentsareusedextensivelyincancerchemotherapy.Theyhaveasteepdose-responsecurveandarethereforeusefulindoseintensificationstrategies(e,g.inbonemarrowtransplantation).Thesubclassesofalkylatingagentsareasfollows.
简介:Riverregulationandrivertraininghavebeenperformedforvariouspurposesandnegativeeffectshavebeenshowninnumerouscases.Insomecasesthenegativeeffectsaresoseriousthathumanshavetoconsiderto'renaturalize'theregulatedrivers.Onlybyusingthestrategyofintegratedrivermanagementthediverseriverusesandnaturalfluvialprocessesandecologicalsystemsmaybeharmonized.Basedonanalysisofcasestudiesanddatacollectedfromliteraturesthispaperpresentstheconceptofintegratedrivermanagementandfourprinciplesofrivertraining.Theintegratedrivermanagementcomprises:1)takingthewatershed,upperstreambasinincludingthetributaries,middleandlowerreachesandtheestuaryasanintegratedentityintheplanning,designandmanagement;and2)mitigatingorcontrollingthenegativeimpactsonhydrology,erosionandsedimentation,fluvialprocesses,landuseandriveruse,environmentandecologywhileinachievingeconomicbenefitfromwaterresourcesdevelopment,floodsafetymanagementandhydropowerexploitation.Rivertrainingandmanagementshouldbeinaccordancewiththefourprinciples:1)extendingthedurationofriverwaterflowingonthecontinent,whichmaybeachievedbyextendingtherivercourseorreducingtheflowvelocity;2)controllingvariouspatternsoferosionsandreducingthesedimenttransportationintherivers;3)increasingthediversityofhabitatandenhancingtheconnectivitybetweentheriverandriparianwaters;and4)restoringnaturallandscapes.
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简介:Thispaperreviewscurrentrecommendationsontheappropriateevaluationandmanagementofcardiacarrhythmiasinthepregnantpatient.Mostarrhythmiasduringpregnancyarebenignandrequirenointervention.Whenrequired,thedecisiontotreatshouldbebasedonsymptomseverityandtheassociatedrisktomotherandfetusposedbypotentiallyrecurringarrhythmiaepisodesthroughoutthepregnancy.Anytreatmentstrategyinthispatientpopulationhasinherentrisktobothmotherandunbornchild.Beforetheinitiationofanyintervention,documentationofaclinicalarrhythmiaandcorrelationwithclinicalsymptomsshouldbeobtained.Thereisnoroleforempirictherapy.
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简介:a translation is a text intended to function for the target receivers and,a. Parking signs borrowed,[8]吕和发.公示语的汉英翻译[J].中国科技翻译.2004(4).
简介:甲醇摘录ofStellerachamaejasmeL被antitumor为antitumor活动估计对鼠科的白血病P388invivo的活跃生物鉴定。摘录的bioassay-directcd分离供应了七diterpene混合物(stellerarin,stelleramacrin,gnidimacrin,pimelea因素P2,subtoxin,huratoxin,simplexin)并且二biflavanone混合物(neochemae茉莉属A和B)。在他们之中,gnidimacrin,stellerarin和stelleramacrin(新奇混合物)被发现对P388,L1210和K562invivoandinvitro有高antitumor和细胞毒素的活动。结果建议diterpene混合物是有势力antitumorprinciplesofStellerachamaejasmeL。
简介:TheheightoftheU.S.strengthisattheperiodfromPresidentClinton'scomingtopowerin1992tilltheendofthelarge-scalebattlesintheIraqwaronMay1,2003.HowAmerica'snationalfortunewilldevelopdependsonhowAmericawillresolvetheIraqissue,implementitsprogramofreformingMiddleEast,andmaintaininsteadofdamagingitsnationalfundamentalprinciplesathome.
简介:Thispaperwillchseussthegeneralizedvariationalprinetples.whichtheestablishedbythemethedofundeterminedmultipliersinstructures.andanalysthestatiedllyindeterminatetruss.inwhichtheseprincipleswillbeused.Atthesametimewebringasymmetricalmatrixandgivespeeitiesohution.thusalltheinternalforeesofstructuresmaybefound.
简介:Withworldpopulationgrowtharablelandareaisdecreasing.Salinesoilisanimportantnaturalresource.Howeverithasnotbeenwellreclaimedowingtoadverseconditions.Forestationisonewayofsaltysoilutilization;ontheotherhand,itcanimprovesoilqualityaswell.Themechanismofsalinitytoleranceisthebasisfortreespeciesselectionwhenplantinginsaltaffectedsoil.Differentplantshavevariouswayofsalinitytolerance,somearesalt-exclusion,e.g.Elaeagnusangustifolia;somearesalt-secretion,e.g.Tamarixspp.;somearesalt-dilution,e.g.Hordeumvulgare;somearesalt-avoidance,e.g.Rhizophoraapiculata.Treesarefavorable,whicharesalttolerantanddroughtorwaterloggingtolerant,aswellasgrowfast.Aftertreespecieshavebeendecided,sitepreparationincludingchangeorexchangeofsoilisnecessary.Meanwhilesuitabledensityoftreesandplantingtimemustbecarefullyconsideredintermsofsoilconditionsandclimaticcharacteristics.Nowalargescaleofforestshasbeenestablishedinsalt-affectedsoilinChinabythemeansdiscussedinthepaper,andprotectforestsystemalongcoastplaysimportantrolesinsocio-economicsustainabledevelopmentandimprovementofeco-environment.