简介：<正>Inthemostrecentreportofinjurydataon15sportsfromtheU.S.NationalCollegiateAthleticAssociation(NCAA)InjurySurveillanceSystemoveraspanof16years(1988-2004),ankleligamentsprainswerethemostcommoninjury.Residualsymptomssuchasrecurrentsprains,pain,instability,andgivingwayarecommonafteraninitial,acuteligamentsprain.Chronicankleinstability(CAI)isoneofthesecommonproblems,andhasenjoyedincreasedinterestintherecentliterature.However,CAIremainsapoorly-definedandunderstoodcondition.

简介：Humanimmunodeficiencyvirus(HIV)hashadaninsightfulimpactaboutthestateofhealthinessofhumanimmunesystem.Duetogreatimprovementindrugtherapy,HIVinfectionshavebeenreducedby17%overthepasteightyears.IthasbeenprovedthatmosteffectivetreatmentHAART(HighlyActiveAntiRetroviralTherapy)mainlycontrolsthediseasesprogressionbutitdoesnoteradicatethediseasescompletely.ReverseTranscriptaseInhibitordrugsspeciallyassociatedwithvirusspecificCytotoxicT-Lymphocyte(CTL)thatdeclineswithdiseaseprogression.CTLresponsesagainstAIDSpathogenesiscouldbepotentialinthedynamicsofvirusreplication,recognitionandclearanceofinfectedcells.InthisresearcharticleamathematicalmodelhasbeenproposedonthebasisofCTLresponsesuppressioninthechronicphaseofinfectionduetopresenceofvirus.WealsoconsiderthegrowthoftheviruspopulationfromtheinfectedCD4~+Tcellsbuddingprocessandfromtheotherinfectedcellslikemacrophagesandthymocytes.Ouranalyticalandnumericalstudiesareconsistentwithexistingobservationsfromalliedareas.

简介：Levofloxacin是通常被用来对待长期的细菌的前列腺炎的合成fluoroquinolone。我们在中国病人为长期的细菌的前列腺炎的治疗与ciprofloxacin相比调查了levofloxacin的安全和功效。这是multicenter，开标签的、使随机化的控制非低劣试用。有临床的症状/症状的471个病人被注册进学习，并且408个病人是微生物学地证实的长期的细菌的前列腺炎，被使随机化到也口头的levofloxacin(500 ；mgq.d)或ciprofloxacin(500 ；mgb.i.d)为4个星期。细菌的清理率，临床的症状/症状，不利反应和疾病复发被估计。临床的症状和症状和在与levofloxacin对待的209个病人和与ciprofloxacin对待的199个病人的细菌文化(包括的尿痛，会阴的不快或疼痛)是类似的。最普通的细菌是Escherichiacoli和葡萄球菌aureus。在4星期治疗的结束以后的一～四个星期，细菌的清理率(86.06%；对60.03%；P<；0.05)并且临床的功效(包括临床的痊愈和临床的改进(93.30%；对71.86%；P<；0.05))比在对待ciprofloxacin的组在对待levofloxacin的组是显著地更高的。microbiological复发率比在对待ciprofloxacin的组在对待levofloxacin的组是显著地更低的(4.00%；对19.25%；P<；0.05)。不利事件和处理相关的不利事件的率比在对待ciprofloxacin的组在对待levofloxacin的组是稍微更低的。Levofloxacin以临床的功效和疾病复发在ciprofloxacin上显示出一些优点，与不利事件的低率，为在中国病人的长期的细菌的前列腺炎的治疗。

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简介：<正>Purpose:Thepurposeofthisstudywastoexamineeffectsofasportversionofasemi-rigidanklebrace(ElementTM)andasoftanklebrace（ASO）onanklebiomechanicsandgroundreactionforces（GRFs）duringadroplandingactivityinsubjectswithchronicankleinstability(CADcomparedtohealthysubjectswithnohistoryofCAI.Methods:Tenhealthysubjectsand10subjectswhohadmultipleanklesprainsparticipatedinthestudyasthecontrolandunstablesubjects,respectively.TheCAIsubjectswereage,bodymassindexandgendermatchedwiththecontrolsubjects.Thearchindexandanklefunctionsofthesubjectsweremeasuredinasubjectscreeningsession.Duringthebiomechanicaltestsession,participantsperformedfivetrialsofdroplandingfrom0.6m,wearingnobrace（NB）.Element?braceandASObrace.Simultaneousrecordingofthree-dimensionalkinematic（240Hz）andGRF（1200Hz）datawereperformed.Results:TheCAIsubjectshadloweranklefunctionalsurveyscores.ThearchindexanddeformityresultsshowedgreaterarchdeformityofElementTMagainstastaticloadthaninNBandASOduetogreaterinitialarchpositionheldbythebrace.CAIparticipantshadgreatereversionvelocitythanhealthycontrols.TheASObracereducedthefirstpeakverticalGRFwhereasElementTMincreased2ndpeakverticalGRF.ElementTMbracereducedeversionrangeofmotion（ROM）andpeakeversionvelocitycomparedtoNBandASO.Inaddition,ElementTMreduceddorsiflexionROMandincreasedpeakplantarflexionmomentcomparedtoNBandASO.Conclusion:Resultsofstaticarchmeasurementsanddynamicanklemotionsuggestthattherestrictionsofferedbybothbracesareinpartduetomoredorsiflexedanklepositionsatcontact,andhigherinitialarchpositionandstifferankleforElementTM.