简介：AbstractBackground:Endoscopic ultrasound (EUS)-guided transmural drainage for pancreatic fluid collections (PFCs) has become the first-line treatment with quicker recovery and more minor injury compared with surgery and percutaneous drainage. The efficacy of stents implantation and drainage for different PFCs remains controversial, especially lumen-apposing metal stents (LAMS). This study aimed to compare the efficacy and safety of LAMS drainage for pancreatic pseudocysts (PPC) and walled-off necrosis (WON).Methods:A meta-analysis was performed for LAMS drainage for WON and PPC by systematically searching PubMed, Cochrane, and Embase databases from January 2010 to January 2020. From 2017 to 2019, 12 patients who were treated with LAMS drainage for PFCs in our medical center were also reviewed and included in this study.Results:Combining 11 copies of documents with the data from our medical center, a total of 585 patients with PFCs were enrolled in this meta-analysis, including 343 patients with WON and 242 with PPC. The technical success rate in WON is not significantly different from that of PPC (P = 0.08 > 0.05). The clinical success of LAMS placement was achieved in 99% vs 89% in PPC and WON, respectively (RR = 0.92, 95% CI: 0.86-0.98, P = 0.01 < 0.05). The further intervention of direct endoscopic necrosectomy was required by 60% of patients in WON group. There was no significant difference in the incidence of adverse events, including infection, bleeding, stent migration and stent occlusion, after LAMS placement between WON and PPC.Conclusions:Endoscopic ultrasound-guided LAMS for PFCs are feasible, effective with preferable technical and clinical success rates. The clinical effect of LAMS on PPC is slightly better than that of WON, but its adverse reactions still need to be verified in a large-sample prospective study.

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简介：<正>声音SOUND"现在我终于拿到了五个总冠军,比奥尼尔多了一个,其实我心里一直都记着这件事情。"科比在进入总决赛之前说他对于冠军并没有什么想法,就只是想要获得总冠军而已。但当他终于再次获得总冠军之后,他还是讲出了心中压抑已久的想法,奥尼尔一直都是他心中试图超越的对象。

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简介：<正>声音"我不怎么喜欢麦迪,无论是在球场上还是球场下。"——小斯在北京时间3月28日太阳战胜尼克斯的比赛后谈起了尼克斯队员麦迪,他表示自己并不是太喜欢麦迪这个人。两人的纠葛来自于2001年,他认为麦迪当时没有给他一个良好的关于职业生涯的建议。

简介：UV-visandluminescencespectroscopictitrationexperimentsshowthatanovelRu(Ⅱ）complexexhibitsoff-on-offpHluminescentswitchingwithamaximumon-offrationofabout100.

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简介：Bymeansoffirst-principlesdensityfunctionaltheory(DFT)calculationsandmoleculardynamics(MD)simulations,aseriesofcoronalmulti-walledsiliconnanotubes(MWSiNTs)withoutorwithhydrogenterminationsaresystematicallyidentified.Notably,coronalMWSiNTs,wheretheinteractionbetweenthewallsispreferablethroughcovalentbondsratherthanweakinteraction,showbetterstabilitythanCNT-likeSiNTs.Moreover,theyexhibitgoodelasticitywithsmallYoung’smodulus.Theinvestigationoftheelectronicstructuredemonstratesthattheypresentmetalliccharacteristics,whichisinstrikingcontrasttobulksilicon.Thus,theMWSiNTsmayfindimportantapplicationsinelectronicdevices.

简介：MrKingisatallandstrongman.HeteachesP.E.inamiddleschool.Hewearsalongheard(胡子)andtakesgoodcareofit.

简介：1991’sDomesticRareEarthEx-hibition,sponsoredbytheLeadingGroupofRareEarthundertheStateCouncilwasheldfromMay21-30intheCulturalPalaceoftheNationalities,Beijing.Itwasthesuccessionofthe1986’s

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简介：A'witkey'isapersonwhosellsknowledgeandexperiencetoothersviatheInternet.Whataretheopportunitiesandchallengesofthisnewandrapidlyexpandingareaofe-commerce?ITwasoneo'clockinthemorning,andHuangWeiguowashunchedoverhiskeyboard,busilyapplyingthefinishingtouchestotheproducthewasabouttosendtohisclientviaawitkeywebsite.Hehadspenttwosimilarlytediouslatenightsstaringathisscreen,makingsurethatthepackagehereturnedwouldbeahigh-qualityjob.'It'saverydemandingjob,butthehourscanbeflexible.What'smore,youcanfindtheworkyouspecializeindirectlyonthesewitkeywebsites.'

简介：SNDisasphericalnon-magneticdetectoroperatingsince1996atVEPP-2Melectron-positroncolliderinNovosibirsk,SNDisperforminganupgradeofitssubsystems,electronics,andsoftwareforthenextrunatVEPP-2000,PresentFortran-basedofflineprogramswillbereplacedwiththeobject-orientedframework,whichsupportssimulation,reconstructionandanalysisactivities,Newframeworkexploitstheexperienceobtainedintheworkwiththecurrentofflineandsupportsorextendsitsessentialfeatures.Themainframeworkconceptisamodule,whichisabasicprocessingunitconsumingsomedataandproducingnewdata.Everymodulecanbeparameterizedduringruntime.Formalizeddescriptionofthemodulesisusedbytheframeworksequencerfortheselectionandorderingofminimalsubsetofmodulesforanygiventask.Datapersistencyservicesaremadesufficientlyabstracttoallowimplementationfordifferentpersistencytechnologies.Prsentlythereisanimplementationforthesequentialfileswithpackeddata.Theframeworkprovidesaninterfaceforscriptinglanguages.Togetherwithacustomexpressionparserthisgivesasupportforextensiblerun-timehistogramming.ThefunctionalprototypeoftheframeworkwasimplementedinPythonlanguageandprovedtheconceptsoftheproject.CurrentlythisprototypeisbeingreimplementedinC++.

简介：Ifthegapbetweentechnologyrichandtechnologypoorwasprimarilyphysicalinthe1990s,thegapinthisdecadeisincreasinglyskills-based.

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简介：AbstractCell death occurs in various tissues and organs in the body. It is a physiological or pathological process that has different effects. It is of great significance in maintaining the morphological function of cells and clearing abnormal cells. Pyroptosis, apoptosis, and necrosis are all modes of cell death that have been studied extensively by many experts and scholars, including studies on their effects on the liver, kidney, the heart, other organs, and even the whole body. The heart, as the most important organ of the body, should be a particular focus. This review summarizes the mechanisms underlying the various cell death modes and the relationship between the various mechanisms and heart diseases. The current research status for heart therapy is discussed from the perspective of pathogenesis.

简介：站在落叶满地的路旁，冷风吹在你的胸膛，此刻的你望着面前一片片枯黄的叶子，也许在思考着什么。这些叶子以它们独有的姿态迎接着生命中的冬天！你的脑海里会不会出现这样一个问题：为什么叶子会落下来呢？是风的召唤，还是树的请求？还是让科学家们来解释一下吧！