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简介：有绗维素酶的帮助的chitosan(72.05%的DD)的降级在45的条件下面被执行，pH5.0并且1:15(chitosan/enzyme)的比率。结果证明绗维素酶能降级chitosan高效地。chitosan的粘性很快速被减少，减少释放的糖在降级期间与时间被增加。由使用膜，水解作用混合的分离被学习。蛋白质的拒绝能被到达是low-molecular-weightchitosans的99.74%.65.9%是不到2kDa。chitosan被发现比chitosan和发射度好的low-molecular-weight的溶解度能到达是在pH的全部范围的超过95%113。

简介：Low-intensityfocusedultrasoundstimulation(FUS),whichpossesseshighspatialresolutionandpenetrationdepth,hasbeendevelopingrapidlyfornoninvasivebrainneuromodulationinrecentyears.Inthisletter,alow-intensityFUSsystemwasdevelopedfornoninvasivebrainneuromodulationinvivo.Theradiusofultrasonicfocalspotwasquantitativelycalculatedintheorytoevaluatethespatialresolution.Thelocalfieldpotential(LFP)ofrathippocompuswererecordedbeforeandafterFUS.TheeffectofFUSonLFPpowerspectrumwasinvestigatedbycomputingtheLFPmeanabsolutepowerandrelativepowerwithWelchalgorithm.TheexperimentresultsshowthatnoninvasiveFUScanenhanceLFPmeanabsolutepowerandaltertheLFPrelativepoweratdifferentfrequencybands.TheresultsindicatethatFUScanmodulatebrainrhythmsandhassignificantpotentialinthemodulationofneuronalandpsychiatricdiseases.