简介：Background:Thoughthemechanismsofskeletalmuscleregenerationaredeeplyunderstood,thoseinvolvedinmusclecontusion,oneofthemostcommonmuscleinjuriesinsportsmedicineclinics,arenot.Theobjectiveofthisstudyistoexplorethemechanismsinvolvedinmuscleregenerationaftercontusioninjury.Methods:Inthisstudy,atotalof72micewereused.Eightofthemwererandomlychosenforthecontrolgroup,whiletherestweresubjectedtomusclecontusion.Subsequently,theirgastrocnemiusmuscleswereharvestedatdifferenttimepoints.Thechangesinmusclemorphologywereassessedbyhematoxylinandeosin(HE)stain.Inaddition,thegeneexpressionwasanalyzedbyreal-timepolymerasechainreaction.Results:Thedatashowedthattheexpressionofmanygenes,i.e.,specificmarkersofimmunecellsandsatellitecells,regulatoryfactorsformuscleregeneration,cytokines,andchemokines,increasedintheearlystagesofrecovery,especiallyinthefirst3days.Furthermore,therewerestrictrulesintheexpressionofthesegenes.However,almostallthegenesreturnedtonormalat14dayspost-injury.Conclusion:Thesequenceofimmunecellsinvadedaftermusclecontusionwasneutrophils,M1macrophagesandM2macrophages.SomeCC(CCL2,CCL3,andCCL4)andCXC(CXCL10)chemokinesmaybeinvolvedinthechemotaxisoftheseimmunecells.HGFmaybetheprimaryfactortoactivatethesatellitecellsaftermusclecontusion.Moreover,2weeksareneededtorecoverwhenacutecontusionhappensasusedinthisstudy.

简介：GA-hardnessandinterdependencebetweengenesinthechromosomeareimportantquestionsinthestudyofgeneticalgorithms(GA).Traditionalmethods,whichareusedtomeasuretheinteractionbetweengenes,canonlyreflecttheextentofepistasisbetweenallgenesinthechromosome.Therefore,thedefinitionofthefitnesslandscapeofschemataisproposedinthispaper,andepistasismeasuresonthislandscapeofschemataareusedtoanalyzethedegreeofinterdependencebetweensomecertaingenelociinstudy.Someinformationbetweenthesesitescanbereflectedbysomecharactersofthefitnesslandscapeofschematawhicharecomposedofthesefixedsites.Thestrongertheinteractionbetweenthesesites,thelargerthevariationofthefitnessofschematawhosefixedsitescorrespondtothosesitesinstudy,andthemoreruggedthefitnesslandscapeoftheseschemata.Accordingtothedegreeofinteractionbetweenthesegivengeneloci,buildingblocksofGAcanbeanalyzedanddetermined,andfurthergeneticoperatorsandthestructureofGAcanbedesignedandadjustedtoimprovetheperformanceofGA.Atlast,alotofexperimentsincludingNK-modelsaredone,andresultsofempiricalanalysisshowthatthismethodiseffective.

简介：为了实现智能家庭服务机器人的人脸跟踪、语音识别、自主移动、动作响应、远程遥控等功能,本智能家庭服务机器人实现了人脸跟踪、语音识别、自主移动、动作响应、远程遥控等功能,家庭服务机器人行走控制

简介：Sincethecarbohydratecontentaffectspearflavorduringtheprocessofgrowth,itisnecessarytodeterminethesugarcomponentsthataccumulateinthefruit.Weanalyzedthefruitcarbohydratecontent,andthegeneexpressionandactivityofacidinvertase(AI),neutralinvertase(NI),sucrosesynthase(SS),andsucrosephosphatesynthase(SPS)duringthedevelopmentof“Huangguan”and“Yali”pears.Theresultsdemonstratethatduringdevelopment,thefruitsugarmetabolismofthe“Huangguan”pearfollowsatypicalsorbitol–starch-solublesugarsmiddlemodel,whereasthe“Yali”pearfruitfollowsatypicalsorbitol–sucrose–starch-solublesugarsmiddlemodel.Inthe“Huangguan”pear,wefoundtheAIandNIgeneexpressions,aswellasAI(P<0.05)andNI(P<0.01)enzymeactivities,tobepositivelycorrelated,whereaswefoundtheNIgeneexpressionandNIenzymeactivityof“Yali”peartobenegativelycorrelated(P<0.01).Weobservedthehighlevelsoflate-stageAIandearly-stageSSduringdevelopmenttoroughlycorrespondwiththegeneexpressionfoundinthelateandearlystages,respectively,suggestingtheirpotentialregulatoryrolesin“Huangguan”pearfruitdevelopment.OurresultsindicatethattheprimaryfunctionofSPSduringtheearlydevelopmentalstageistoaccumulatesucrose,whereastheprimaryfunctionofAIistopromotehexoseaccumulationduringthelatedevelopmentalstageofmature“Yali”pearfruit.