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239 个结果
  • 简介:Purpose:Theaimofthisstudywastoextendcurrenthalf-sarcomeremodelsbyinvolvingarecentlyfoundforce-mediatedactivationofthethickfilamentandanalyzetheeffectofthismechanosensingregulationonthelengthstabilityofhalf-sarcomeresarrangedinseries.Methods:Weincludedasuper-relaxedstateofmyosinmotorsanditsforce-dependentactivationinaconventionalcross-bridgemodel.Wesimulatedactivestretchesofasarcomereconsistingof2non-uniformhalf-sarcomeresonthedescendinglimboftheforce-lengthrelationship.Results:Themechanosensingmodelpredictsthat,inapassivesarcomereonthedescendinglimboftheforce-lengthrelationship,thelongerhalf-sarcomerehasahigherfractionofmyosinmotorsintheon-statethantheshorterhalf-sarcomere.Thedifferenceinthenumberofmyosinmotorsintheon-stateensuresthatuponcalcium-mediatedthinfilamentactivation,theforce-dependentthickfilamentactivationkeepsdifferencesinactiveforcewithin20%duringanactivestretch.Intheclassicalcross-bridgemodel,thecorrespondingdifferenceexceeds80%,leadingtogreatlengthinstabilities.Conclusion:Oursimulationssuggestthat,incontrasttotheclassicalcross-bridgemodel,themechanosensingregulationisabletostabilizeasystemofnon-uniformhalf-sarcomeresarrangedinseriesonthedescendinglimboftheforce-lengthrelationship.

  • 标签: Force-length relationship Instability Mathematical modelling Myofibril
  • 简介:HowcanteachersteachEnglishwritingeffectively?Andhowcanstudentslearntowriteessayscorrectly?TheseseemtobetwopuzzlingproblemsforChineseteachersandlearners.Thispaperaimstointroduceanewteachingapproach:theLengthApproach,anddiscussesitsmerits.

  • 标签: ENGLISH LANGUAGE TEACHING ENGLISH WRITING LENGTH
  • 简介:MeasurementforElectricalLengthofCables¥LiJi;ZhengJianhua;YeFengandChuZhengshengItisimportanttomatchcableelectricallengthinthe...

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  • 简介:Forgivendata(ti,yi),I=0,1,…,n,0=t0<t1<…<tn=1westudyconstrainedinterpolationproblemofFavardtypeinf{‖f'‖∞|f∈W2∞[0,1],f(ti)=yi,i=0,…,n,l(f;[0,1])≤l0},wherel(f';[0,1])=∫10/1+f'2(x)dxisthearclengthoffin[0,1].Weprovetheexistenceofasolutionf*oftheaboveproblem,thatisaquadraticsplinewithasecondderivativef'*,whichcoincideswithoneoftheconstants-‖f'*‖∞,0,‖f'*‖∞betweeneverytwoconsecutiveknots.Thus,weextendaresultofKarlinconcerningFavardproblem,tothecaseofrestrictedlengthinterpolation.

  • 标签: 弧长 分割 插值 节点 二次样条
  • 简介:英文原名:G-Force中文译名:豚鼠特工队/超鼠特攻/鼠胆妙算电影宣传语:Theworldneedsbiggerheroes.

  • 标签: 小学 英语教学 教学方法 阅读
  • 简介:AbstractBackground and objective:The size of the cochlea varies a lot among the human population bringing the necessity for electrode arrays to be available in various lengths irrespective of the cochlear implant (CI) brand. This research software helps in the estimation of the patient’s cochlear duct length (CDL) which is then used for the simulation of the correct length electrode array matching the patient’s cochlear size and as well in getting the patient specific cochlear frequency map.Methods:Visual Studio Express 2012 for Windows Desktop is used in the architecture of this research software. The basal turn diameter of the cochlea ( "A" value) needs to be measured from the pre-operative computed tomography (CT) image of the patient’s temporal bone. This "A" will be taken as the input for the CDL equations proposed by Alexiades et al for estimating the CDL along the basilar membrane for various insertion depths. Greenwood’s equation is then used in combination with the CDL for the full length of the cochlea in getting the patient specific frequency map.Results:The research software with the help of the "A" value as input, with few button clicks, gives the patient specific CDL for various insertion depths and the Greenwood’s frequency map. The users have the choice to select any electrode array of their choice and place it under the frequency map to see how good it fits to that particular patient’s cochlea. Also, given the possibility to drag and move the electrode array picture to mimic the post-operative actual electrode insertion depth.Conclusions:This research software simplifies the overall process of CDL estimation and in getting the patient specific cochlear frequency map. The clinicians get the chance to simulate placing the various electrode array lengths in patient cochlea in identifying the best fit electrode. This could help in pushing the CI field into the concept of individualized CI electrode array solution that ultimately benefits the patients.

  • 标签: Cochlear duct length Greenwood frequency map Electrode array
  • 简介:D-Force是一家以桌球游戏为主的娱乐会所。游戏如一场微缩的故事,开局、角逐、高潮、结局;游戏拥有许多戏剧的元素,从不明朗的开局到最终的胜负,中间的角逐就是游戏的魅力。D-Force企图用空间去表达这种游戏的状态。

  • 标签: 会所 游戏 娱乐
  • 简介:Surfaceeffectsonthepersistencelengthofquasi-one-dimensionalnanomaterialsareinvestigatedbyusingthetheoryofsurfaceelasticityandthecore–shellmodelofnanobeams.Asimpleandunifiedexpressionisprovidedtodeterminethepersistencelengthofnanowiresandnanotubeswithanyregularpolygonalcross-sections.Itisdemonstratedthatsurfaceeffectshaveadistinctinfluenceonthepersistencelengthwhenthecharacteristicsizesofmaterialsshrinktonanometers.Thisworkishelpfulnotonlyforunderstandingthesize-dependentbehaviorofnanomaterialsbutalsoforthedesignofdevicesbasedonnanotubesornanowires.

  • 标签: 表面效应 纳米管 纳米线 长度 一维纳米材料 尺寸缩小
  • 简介:Classicalsortingbyreversalsusestheunit-costmodel,thatis,eachreversalconsumesanequalcost.Thismodellimitsthebiologicalmeaningofsortingbyreversal.Benderandhiscolleaguesextendeditbyassigningacostfunctionf(l)=lαforallα≥0,wherelisthelengthofthereversedsubsequence.Inthispaper,weextendtheirresultsbyconsideringamodelinwhichlongreversalsareprohibited.Usingthesamecostfunctionaboveforpermittedreversals,wepresenttightornearlytightboundsfortheworst-casecostofsortingbyreversals.Thenwedevelopalgorithmstoapproximatetheoptimalcosttosortagiven0/1sequenceaswellasagivenpermutation.OurproposedproblemsaremorebiologicallymeaningfulandmorealgorithmicallygeneralandchallengingthantheproblemconsideredbyBenderetal.Furthermore,ourboundsaretightandnearlytight,whereasouralgorithmsprovidegoodapproximationratioscomparedtotheoptimalcosttosort0/1sequencesorpermutationsbyreversals.

  • 标签: 资料排架 生物学 长度限制 生长逆转
  • 简介:Basedontheperiodicstructureofcodeworksoflinearblockcodes,anewideaoflength-varyingcodingdigitalcommunicationssystemisproposedtosavethechannel.Itisshown,byexample,thatupto1/3ofchannelcapacitycanbesavedbythenewsysteminsomespecialsituations.Inordertofindwhichblockcodeissuitabletouseinlength-varyingcodingsystem,theperioddistributionofthecodehastobecal-culated.Newrwsultsabouttheperioddistributionarepresentedwhilemanyopenproblemsremain.

  • 标签: 编码 周期分配 长度变化 数字通信系统 分组码
  • 简介:Magneticforcetransmissionofareciprocatingmotionisstudiedbytheoreticalanalysisandexperiment.Amathematicalmodelforcalculatingthemagneticforceisderivedusingthetheoryofequivalentmagneticcharges.Anexperimentalrigisconstructedtotestthetransmissionandthemodelisverifiedbyexperiment.Effectofthetransmissionparametersonthemagneticforceisanalyzedtheoreticallyfromthemodel,andcharacteristicofthetransmissionisstudiedexperimentally.Sincethetransmissioniswithoutdirectcontactbetweentwoelements,itissuitableforapplicationinanorganism.

  • 标签: 往复运动 磁力 理论分析 数学模型
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  • 简介:一条高速公路在江西省被构造,中国,彻底地多山的区域。高速公路的一些节通过了在哪儿的山谷6的软泥土层-8.5m深被遇到。一个新爆炸方法为这个工程被开发并且采用。在这个方法,爆炸被用来与压碎的石头移开并且代替软泥土。爆炸费用被放在根据某个模式要改善的土壤。压碎的石头在费用被安装的区域后面被积累。爆炸在爆炸区域移开大多数土壤并且引起压碎的石头的堆积滑动进土壤被爆炸移开的区域。Aformular被建议计算使用改进土壤的某个类型的费用重量。方法的Theeffectiveness用地上凿穿探索被评估,板负担测试,探查andground雷达测试。

  • 标签: 爆炸力 人行道 公路 基础改进
  • 简介:IntroductionDigitalstronggroundacelerationobservationinstrument,suchasPDR1,SSA1andSSR1producedbyKinemetricsInc.,USAandSCQ?..

  • 标签: successive FORMULA method\ FORCE BALANCED accelerometer\