简介:目的:为临床利用带血供肌蒂锁骨瓣提供应用解剖学资料。方法:在50侧成人上肢标本上解剖观测锁骨的形态、血供来源、分支、分布特点及其间的吻合。结果:锁骨长13.9±0.7cm,最窄处矢状径为1.2±0.4cm;血供主要来源于胸肩峰动脉的分支。其次还通过附着于其上的肌肉获得营养;颈横动脉、肩胛上动脉也有分支到达锁骨。结论:应用锁骨的血供特点和肌肉的附着特点,可设计带血管或肌蒂的半片锁骨骨(膜)瓣,转位移植修复下颌骨缺损、肱骨骨不连及行颈椎前路植骨。
简介:垂体瘤是常见的颅内肿瘤之一,约占颅内肿瘤的10-15%[1]。目前对垂体瘤的病因和发病机理还没达到统一的认识。手术治疗垂体瘤仍有相当多的复发病例,垂体瘤理想的治疗方法仍众说不一。为了更深入地研究垂体瘤的发病机理,并探索一种治疗垂体瘤的有效途径,在动物体内建立类似人类垂体瘤的模型是垂体瘤基础理论研究的重要课题。1自发性垂体瘤动物模型肝(spontaneousanimalmod-elsofpituitarytumors)动物自发性垂体瘤动物模型的发生率相当低,其发生率取决于动物的种系、性别和年龄。雌性64~135周龄的Wistar-Fulth(W/Fu)大鼠自发性垂体瘤的发生率高达69%,而雄性7
简介:Toverifytheanti-tumoureffectsofpolyscaccharideisolatedfromTangerineskinonmicetransplantabletumour,andtodevelopanewanticancerdrugfromplant.MiceweretransplantedwithS-180sarcomaorEhrhch'sasciticcarcinomaandhumanhysterotrachecarcinomaHelaceli.Drugsweregivendaily,byoraladministration.Forsevendays,ontheeighthdayanimalsweresacrificed.Peripheralbloodcellcounts,aswellasplasmasupemxidedismutase(SOD),malondialdehyde(MDA)andredbloodcellimmunityfunctiondetermination.TheinhibitionrateofTangerineskinpolysaccharideformiceS-180andEACwere21.6%and27.3%respectively.'FneeffecttoHealcellweredeteminedbyMTT.TheeffectofTangerineskinpolysccharideonperipheralbloodcountswereincreasednumbersofperipheralleukocytesandlymphocytes,theTangerineskinpolysaccharidegroupwashigherthanAnliurugroup(P<0.01).PlasmSODactivitywereincreased,MDAcontentdepressed,butnodifference.Redbloodceilimmunefunctionincreased(P<0.01).TheinhibitionrateforhumanhysterotrachecarcinomaHelaceilwere52.4%,63.0%and72.0%.Tangerineskinpolysaccharideexhibitedanti-canceractivityandmayincreaseperipheralleucocytecountandnumberoflymphocytesandenhanceimmunompetece.Itispromisinginadjuvanttherapy.Furtherstudyisworthcontinuing.