Despitethehugedevelopmentofradiofrequencycatheterablation,surgicaloperation,pacemakerimplantation,anddrugtherapyremainsthefirstlinetreatmentofatrialfibrillation.Severalnewanti-arrhythmicdrugsandanticoagulationdrugshavecomeoutrecently,andhavemadethedrugtherapyofatrialfibrillationamorepromisingchoice.Thisarticleprovidesacontemporaryhighlightonthenewanti-arrhythmicagentsofatrialfibrillation.