SARS Vaccine: Progress and Challenge

(整期优先)网络出版时间:2005-02-12
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Severeacuterespiratorysyndrome(SARS)emergedin2002asasevereandhighlycontagiousinfectiousdiseasethatrapidlyspreadtoanumberofdifferentcountries.Thecollaborativeeffortsoftheglobalscientificcommunityhaveprovided,withinashortperiodoftime,substantialinsightsintothemolecularbiologyandimmunologyofSARS-CoV.Althoughtheoutbreakhasbeencontained,thereiscontinuousconcernthatthevirusmayresurfaceintothehumanpopulationthroughseasonalchanges,animalreservoirsorlaboratoryaccidents.TheseveremorbidityandmortalityassociatedwithSARSmakeitimperativethataneffectivevaccinebedevelopedtopreventreemergenceandepidemicsinthefuture.Cellular&MolecularImmunology.2005;2(2):101-105.