An ultrasound simulation method for carotid arteries with a wall structure of three membranes

(整期优先)网络出版时间:2015-03-13
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Ultrasoundsimulationforcarotidarteriesishelpfultotheperformanceassessmentsofvesselwalldetectionandsignalprocessingmethodsbyusingultrasoundtechniques.Anultrasoundsimulationmethodofcarotidarterywallwithathree-membranestructureisproposedinpresentstudy.Accordingtotheultrasoundspeckledistributionsvaryingwiththeshapesanddensitiesofscattererdistributions,aswellasthestatisticresultsoftheclinicalimages,theparametersofdistributions,densitiesandintensitiesofscatterersfordifferentkindsoftissuesinthecarotidarteryphantomsaredetermined.EachregionisacousticallycharacterizedusingFIELDIIsoftwaretoproducetheradiofrequencyechosignals,fromwhichultrasoundimagesarederived.Theresultsbasedon30simulationsshowthattheechodistributionsoftheintimae,mediae,adventitiasandbloodareconsistentwiththeclinicalones.Moreover,comparedwiththeresultsfromthecentralfrequencyof8MHz,themeanmeasurementsforthicknessesoftheintima,mediaandadventitiamembranes,aswellasthelumendiameterfromthesimulationimagesbasedon12MHzarethesameasthepresetones,andthemaximumrelativeerrorsarethe4.01%,1.25%,0.04%and0.15%,respectively.Thesimulationunderthisconditionismorerealistic.