Elementary study on the antigenicity of SARS-CoV Mc region-中国期刊网

摘要 TotesttheantigenicactivityofMprotein(Mcprotein)intheinnermembraneofSARS-CoV,SARS-CoVMcprotein'sbaseslocatinginsidethemembranewerecloned,theHis-fusionproteinwasexpressedinE.coliandanalyzedforitsantigenicactivity.Amongthose7clinicallydiagnosedpatients'sera,therewere5positiveand2negativeinreactionwithHis-fusionprotein.Allofthe20healthypersons'seraandrabbitanti-OC43and229EwereofnegativereactionwithHis-fusionprotein.TheanimalsimmunizedwithHis-fusionproteinhaveproducedmulti-clonalantibody.TheHis-fusionproteincouldspeciallyreactwithclinicallydiagnosedSARSpatients'seraandtheanimalsimmunizedwithHis-fusionproteincouldproducespecificallymulti-clonalantibody,butitcouldnotreactwiththeseraofhealthypersonsandtherabbitanti-OC43and229E.

1JingqiangWang;JiaJi;JiaYe;XiaoqianZhao;JieWen;WeiLi;JianfeiHu;DaweiLi;MinSun;HaipanZeng;YongwuHu;XiangjunTian;XuehaiTan;NingzhiXu;ChangqingZeng;JianWang;ShengliBi;HuanmingYang. The Structure Analysis and Antigenicity Study of the N Protein of SARS-CoV.分子生物学,2003-02.
2JingxiangLi;ChunqingLuo;YajunDeng;YujunHan;LingTang;JingWang;JiaJi;JiaYe;FanboJiang;ZhaoXu;WeiTong;WeiWei;QingrunZhang;ShengbinLi;WeiLi;HongyanLi;YudongLi;WeiDong;JianWang;ShengliBi;HuanmingYaug. The Structural Characterization and Antigenicity of the S Protein of SARS-CoV.分子生物学,2003-02.
3Gordana M. Pavlovic-Lazetic;Nenad S. Mitic;Andrija M. Tomovic;Mirjana D. Pavlovic;Milos V. Beljanski. SARS-CoV Genome Polymorphism： A Bioinformatics Study.分子生物学,2005-01.
4ShutingLi LiangLin HaoWang JianningYin YanRen ZheZhao JieWen CuiqiZhou XuminZhang XiaoleiLi JingqiangWang ZhengfengZhou JinxiuLiu JianminShao TingtingLei JianqiuFang NingzhiXu SiqiLiu. The Epitope Study on the SARS-CoV Nucleocapsid Protein.分子生物学,2003-03.
5GuozhenLiu;ShaohuiHu;YongwuHu;PengChen;JianningYin;JieWen;JingqiangWang;LiangLin;JinxiuLiu;BoYou;YeYin;ShutingLi;HaoWang;YanRen;JiaJi;XiaoqianZhao;YongqiaoSun;XiaoweiZhang;JianqiuFang;JianWang;SiqiLiu;JunYu;HengZhu;HuanmingYang. The C-Terminal Portion of the Nucleocapsid Protein Demonstrates SARS-CoV Antigenicity.分子生物学,2003-03.
6JingXu;JianfeiHu;JingWang;YujunHan;YongwuHu;JieWen;YanLi;JiaJi;JiaYe;ZizhangZhang;WeiWei;SonggangLi;JunWang;JianWang;JunYu;HuanmingYang. Genome Organization of the SARS-CoV.分子生物学,2003-03.
7JianfeiHu;JingWang;JingXu;WeiLi;YujunHan;YanLi;JiaJi;JiaYe;ZhaoXu;ZizhangZhang;WeiWei;SonggangLi;JunWang;JianWang;JunYu;HuanmingYang. Evolution and Variation of the SARS-CoV Genome.分子生物学,2003-03.
8WenbingChen ShousongLi BiyingShao TengZheng ShuxunJiang XiaorongHuan KaizhenCai ZhidengZhang. Preliminary Study on Detecting the SARS-CoV Specific Target cDNA Fragments by Multiplex PCR.分子生物学,2004-01.
9QingfaWu;YilinZhang;HongLu;JingWang;XimiaoHe;YongLiu;ChenYe;WeiLin;JianfeiHu;JiaJi;JingXu;JiaYe;YongwuHu;WenjunChen;SonggangLi;JunWang;JiauWang;ShengliBi;HuanmingYang. The E Protein Is a Multifunctional Membrane Protein of SARS-CoV.分子生物学,2003-02.
10JunWang;SiqiLiu;ChangqingZeng;JianWang;HuanmingYang;YongwuHu;JieWen;LinTang;HaijunZhang;XiaoweiZhang;YahLi;JingWang;YujunHan;GuoqingLi;JianpingShi;XiangjunTian;FengJiang;XiaoqianZhao. The M Protein of SARS-CoV： Basic Structural and Immunological Properties.分子生物学,2003-02.

Elementary study on the antigenicity of SARS-CoV Mc region

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Elementary study on the antigenicity of SARS-CoV Mc region

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