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2015年6期
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西利宾胺在抗痨治疗中的保肝作用
西利宾胺在抗痨治疗中的保肝作用
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摘要
摘要目的讨论西利宾胺在肺结核抗痨治疗中保护肝脏的作用。方法回顾性分析200例初治肺结核病人分为观察组和对照组,均予以2EHRZ/4HR标准方案抗痨治疗,观察组加西利宾胺保肝,对照组无任何保肝药物。结果观察组发生药物性肝功能损害的为8%,对照组发生药物性肝功能损害的为34%。结论西利宾胺能显著降低肺结核患者抗痨治疗后药物性肝功能损害的发生率,减少因抗痨药物所致肝功能损害而造成的不规则治疗。
DOI
2d3m6ky849/3840791
作者
金婷
机构地区
金婷(上海市复旦大学附属中山医院青浦分院201700)
出处
《医师在线》
2015年6期
关键词
抗痨治疗
肝功能损害
西利宾胺中图分类号
R2
文献标号
A
文章编号
2095-7165(2015)11-0005-01Hepatoprotective
effects
of
silybin
meglumine
tablets
in
the
treatment
of
tuberculosisAbstractObjective
to
discuss
the
liver
protection
and
anti
tuberculosis
of
silybin
meglumine
tablets
in
treatment
of
pulmonary
tuberculosis
patients
ineffect.
Methods
a
retrospective
analysis
of
200
cases
of
initially
treated
pulmonary
tuberculosis
patients
were
divided
into
observation
group
and
controlgroup.
All
of
them
2EHRZ/4HR
standard
anti
tuberculosis
treatment
were
observed
in
the
group
Jiaxilibin
of
amine
hepatoprotective
control
groupwithout
any
hepatoprotective
drugs.
Results
the
occurrence
of
drug-induced
liver
damage
in
the
observation
group
was
8%
and
the
control
group
was34%.
Conclusion
silybin
meglumine
tablets
can
significantly
reduce
the
incidence
of
drug-induced
liver
damage
after
anti
tuberculosis
treatment
in
patientswith
pulmonary
tuberculosis
reduced
due
to
anti
tuberculosis
drugs
induced
liver
function
damage
caused
b
分类
[医药卫生][临床医学]
出版日期
2015年06月16日(中国期刊网平台首次上网日期,不代表论文的发表时间)
相关文献
1
康娅;刘聪;岳永花;康永;倪艳;郝旭亮.
抗痨复肝胶囊止咳祛痰、保肝复肝作用的实验研究
.药学,2014-02.
2
王玉彬.
西利宾胺预防抗结核药所致肝损害的临床观察
.呼吸系统,2012-01.
3
夏六均.
西利宾胺联合甘利欣治疗慢性重度乙肝48例
.免疫学,2013-06.
4
邵蕊陈广龙.
肺结核治疗中西利宾胺的护肝疗效分析
.临床医学,2016-03.
5
陈敏张树青.
还原型谷胱甘肽联合水飞蓟宾治疗抗痨所致药物性肝损害的疗效
.免疫学,2012-12.
6
杨淑华.
肝痨中医治疗
.公共卫生与预防医学,2011-06.
7
巴桑旺堆.
酒肝合并结核病的抗痨选择
.文化科学,2011-04.
8
李金元.
抗痨药引起肝损害的多因素分析
.免疫学,2015-12.
9
白靓.
不同性别年龄在抗痨药物性肝损害治疗中的影响分析
.公共卫生与预防医学,2015-12.
10
陆友金.
抗痨治疗中并发症的处理
.呼吸系统,2002-01.
来源期刊
医师在线
2015年6期
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相关关键词
抗痨治疗
肝功能损害
西利宾胺中图分类号
R2
文献标号
A
文章编号
2095-7165(2015)11-0005-01Hepatoprotective
effects
of
silybin
meglumine
tablets
in
the
treatment
of
tuberculosisAbstractObjective
to
discuss
the
liver
protection
and
anti
tuberculosis
of
silybin
meglumine
tablets
in
treatment
of
pulmonary
tuberculosis
patients
ineffect.
Methods
a
retrospective
analysis
of
200
cases
of
initially
treated
pulmonary
tuberculosis
patients
were
divided
into
observation
group
and
controlgroup.
All
of
them
2EHRZ/4HR
standard
anti
tuberculosis
treatment
were
observed
in
the
group
Jiaxilibin
of
amine
hepatoprotective
control
groupwithout
any
hepatoprotective
drugs.
Results
the
occurrence
of
drug-induced
liver
damage
in
the
observation
group
was
8%
and
the
control
group
was34%.
Conclusion
silybin
meglumine
tablets
can
significantly
reduce
the
incidence
of
drug-induced
liver
damage
after
anti
tuberculosis
treatment
in
patientswith
pulmonary
tuberculosis
reduced
due
to
anti
tuberculosis
drugs
induced
liver
function
damage
caused
b
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