Glutathione as the End Capper for Cyclodextrin/PEG Polyrotaxanes-中国期刊网

摘要 Afacileone-potsynthesisofα-cyclodextrin-basedpolyrotaxane(PR)inaqueoussolutionisreported,wherethepeptideglutathionewasusedastheend-cappingagentandthethiol-eneMichaeladditionwasusedastheend-cappingreaction.Bothpolyrotaxaneswithlowthreadingratioandhighthreadingratioweresuccessfullyobtained.Incontrasttotheconventionallyusedmultiple-stepsynthesismethodsandhydrophobicendcappers,thisone-potaqueoussynthesisaswellasthebiocompatibilityoftheend-cappingagentcouldresultinamuchmorebiocompatiblePRtobeusedasbiomaterials.

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Glutathione as the End Capper for Cyclodextrin/PEG Polyrotaxanes

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Glutathione as the End Capper for Cyclodextrin/PEG Polyrotaxanes

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