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简介：AbstractBackground:Whether regional anesthesia may help to prevent disease recurrence in cancer patients is still controversial. The stage of cancer at the time of diagnosis is a key factor that defines prognosis and is one of the most important sources of heterogeneity for the treatment effect. We sought to update existing systematic reviews and clarify the effect of regional anesthesia on cancer recurrence in late-stage cancer patients.Methods:Medline, Embase, and Cochrane Library were searched from inception to September 2020 to identify randomized controlled trials (RCTs) and cohort studies that assessed the effect of regional anesthesia on cancer recurrence and overall survival (OS) compared with general anesthesia. Late-stage cancer patients were primarily assessed according to the American Joint Committee on Cancer Cancer Staging Manual (eighth edition), and the combined hazard ratio (HR) from random-effects models was used to evaluate the effect of regional anesthesia.Results:A total of three RCTs and 34 cohort studies (including 64,691 patients) were identified through the literature search for inclusion in the analysis. The risk of bias was low in the RCTs and was moderate in the observational studies. The pooled HR for recurrence-free survival (RFS) or OS did not favor regional anesthesia when data from RCTs in patients with late-stage cancer were combined (RFS, HR= 1.12, 95% confidence interval [CI]: 0.58-2.18, P = 0.729, I2 = 76%; OS, HR= 0.86, 95% CI: 0.63-1.18, P = 0.345, I2 = 48%). Findings from observational studies showed that regional anesthesia may help to prevent disease recurrence (HR = 0.87, 95% CI: 0.78-0.96, P = 0.008, I2 = 71%) and improve OS (HR = 0.88, 95% CI: 0.79-0.98, P = 0.022, I2 = 79%).Conclusions:RCTs reveal that OS and RFS were similar between regional and general anesthesia in late-stage cancers. The selection of anesthetic methods should still be based on clinical evaluation, and changes to current practice need more support from large, well-powered, and well-designed studies.

简介：摘要：特征近来新生代构造Qinghai西藏高原的南部的边缘高举可以在Zanda盆从fluvio湖的阶层被推断，Ngari，西藏。在盆的厚fluvio湖的阶层是老的5.890.78妈并且他们的免职为5.11妈坚持了的Magnetostratigraphic学习表演，即在结束开始在早更新世的结束中新世、结束，在比1.58妈没有迟了的区域以第四级的冰川的阶段开始。沉积环境的分析显示高原开始了的南部的Qinghai西藏上的Zanda盆在5.89妈，高举比北Qinghai西藏高原迟了。在Guge和Qangz的石子床的存在

简介：Accordingtofieldinvestigationandinterpretationofremotesensingimages,thenorthsegmentoftheLongling-RuilifaultisaHolocenedextralstrike-slipfaultwithasmallamountofnormalfaulting.Basedonlarge-scalegeologicalmappingatsometypicallocationsandquantitativegeomorphologicdeformationmeasurementanddatinganalysis,thisfaultisaHoloceneactivefault.Thestrike-sliprateoftheLongling-Ruilifaultis2.2~2.5mm/aandverticalsliprateis0.6mm/asincethelatePleistoceneepoch.Thestrike-sliprateoftheLongling-Ruilifaultis1.8~3.0mm/aandverticalsliprateis0.5mm/asincetheHoloceneepoch.BasedonthePoissonmodel,lognormalmodelandBPTmodel,theoccurrenceprobabilityofstrongearthquakesin50yearsisestimatedtobe6.32%,0.08%and0.05%,respectively.Then,a1.82%probabilityofoccurrenceofcharacteristicearthquakeforthenorthsegmentoftheLongling-Ruilifaultisobtainedbysettingaweightof0.28,0.36and0.36tothePoissonmodel,lognormalmodelandBPTmodel,respectively.

简介：WehavecarefullyreadthedescriptionoftheproposedmechanismsofhamstringmusclestraininjurybyLiuetal.1andnoticedthattheysuggestthathamstringstraininjuriesmaybeassociatedwithextensivemuscleforceandoccurduringtheearlystancephaseofsprintingwhenthehamstringsarethoughttoworkconcentrically.Wedidnotfindanyevidenceinourextensiveliteraturereviewtosupportthisparticular

简介：AnanalysisofseismicdataobtainedthroughacableroutesurveystartingfromtheQingdaocoasttooffshorehasdeterminednineseismicunitssinceLatePleistocene.CorrelationoftheseismicdatawithBoreholeHi2confirmsthreeeustaticeventsthatoccurredduringtheLateQuaternaryandformedterrestrialunits2,5and7.Atthelowsealevelstage,paleo-rivershighlydeveloped,erodedpreviousstrata,formedpaleo-valley,andleftmaterials.

简介：晚第四级沿着东方Kunlun差错的Maqu片断滑动率用高分辨率的遥感形象解释，地观察和微分全球放系统(GPS)的联合被估计偏移量河平台的大小，和14从偏移量起床人收集的蜗牛壳标明日期的C。结果证明沿着片断的离开滑倒率是3-5mm/a，并且垂直滑倒率是0.3-0.5mm/a。两水平、垂直在在∼100km的距离上一致的片断遗体上滑倒。当以前建议了，它意味着不滑动坡度沿着Maqu片断发生了，并且它可能因此作为一个独立seismogenic差错表现。在年轻梯田之中从多重关系判定抵消，我们推断典型地震在Maqu差错上与Ms7.0-7.5的大小生产的那co地震的表面破裂能产生一水平4.5-5m滑倒并且一垂直0.45-0.5m滑倒，与大约9的相应比率(Dh/Dv)。二个表面破裂事件肯定发生在过去的3300年，最近的可能在1485calBP和1730calBP之间。

简介：TheLateCretaceousMambagranodioritebelongstoapartoftheMesozoicGangdesecontinentalmagmaticbelt.Noquantitativemineralogicalstudyhasbeenmadehitherto,andhencethedepthatwhichitformedispoorlyconstrained.HerewepresentmineralogicaldatafortheMambapluton,includinghostrocksandtheirmaficmicrogranularenclaves(MMEs),toprovideinsightsintotheiroverallcrystallizationconditionsandinformationaboutmagmamixing.AllamphibolesintheMambaplutonarecalcic,with~B(Ca+Na)>1.5,andSi=6.81–7.42apfuforthehostrocksandSi=6.77–7.35apfufortheMMEs.Theparamountcationsubstitutionsinamphiboleincludeedenitetypeandtschermakitetype.BiotitesbothinthehostrocksandtheMMEscollectivelyhavehighMgO(13.19wt.%–13.03wt.%)contents,butdefineanarrowrangeofAlapfu(atomsperformulaunit)variations(2.44–2.57).TheoxygenfugacityestimatesarebasedonthebiotitecompositionsclusteraroundtheNNObuffer.Thecalculatedpressurerangesfrom1.2to2.1kbaraccordingtothealuminum-in-hornblendebarometer.Thecomputedpressurevariesfrom0.9to1.3kbarbasedonthealuminum-in-biotitebarometerwhichcorrespondstoanaveragedepthofca.3.9km.Besides,theestimatesofcrystallizationpressuresvaryfrom0.8to1.4kbarbasedontheamphibolebarometerproposedbyRidolfietal.(2010),whichcanbeequivalenttothedepthsrangingfrom3.1to5.2km.TheMMEshaveplagioclaseoscillatoryzoningsandquartzaggregates,probablyindicatingthepresenceofmagmamixing.Besides,core-to-rimelementvariations(Rb,Sr,Ba,andP)fortheK-feldsparmegacrystsserveasrobustevidencetosupportmagmamixingandcrystalfractionation.ThisindicatesthesignificanceofthemagmamixingthatcontributestotheformationofK-feldsparmegacrystzoningsintheMambapluton.

简介：TheLateCenozoicstratigraphicsequenceanditsinformationoftectonicevolutionareobtainedherethroughthedetailedpetrostratigraphicandmagnetostratigraphicstudyandresearchofstratigraphiccontactandsedmentaryfacesoftheCenozoicstrataprofile,Hejiakouziarea,NingxiaHuiAutonomousRegion.TheintenseCenozoictectonicdeformationbeganat10MaBPintheHaiyuan-TongxinSyntaxis,thenortheasternmarginofQinghai-XizangPlateau,andafewdeformationeventsoccurredduringLateCenozoicEra.

简介：Longling-Ruili差错是在西南的中国的一个重要活跃差错，向东北通常罢工。差错沿着它在Longling盆，Mangshi盆和Zhefang盆的它的二个方面，以及发展上控制沉积系列和magmatic行动的发展。由于有限第四级的沉积和严厉自然条件，Longling-Ruili差错的北片断上的近来第四级的差错活动正在缺乏的学习和最新的指责的时间并且第四级滑倒率不目前是清楚的。基于遥远的图象的解释，量的geomorphologic变丑大小并且年轻平台存款和冲积扇子，标明日期这份报纸如下获得一些新结果。Longling-Ruili差错的北片断是有正常的某部件的一个Holocene右罢工滑倒差错滑倒。主要在4kaB.P期间形成的冲积存款创作的平台T1。是由Longling-Ruili差错的北片断的偏移量并且它的左侧面并且它的垂直排水量分别地是8m12m和2m。迟了的更新世冲积扇子分别地与70m和18m的左侧面、垂直的排水量被代替。Longling-Ruili差错的罢工滑倒率是2.2mm/a2。5mm/a并且垂直滑倒率是0。6mm/a自从迟了的更新世时代。Longling-Ruili差错的罢工滑倒率是1.8mm/a3.0mm/a并且垂直滑倒率在Holocene时代期间是0.5mm/a。比例对垂直排水量水平是大约4：1，它意味着垂直在Longling-Ruili差错的北片断上滑动率是大约25%水平滑倒率。左侧面在迟了的Holocene滑动率与GPS测量一致。罢工滑倒自从迟了的更新世时代，率具有在不同时间规模的大一致性，显示Longling-Ruili的活动指责稳定性大。

简介：在Qinghai西藏的高原附近散布的活跃差错的kinematics的定量分析是批评的理解高原的当前的构造过程。按年代先后的分析基于在地区性的气候和地形学之中的比较，数字摄影测量学，偏移量地形，和tectonics在东方西藏的高原在Xianshuihe差错上在这研究被采用。二或更多的偏移量年龄数据为Xianshuihe和Yunongxi差错的每个片断被获得。包括河梯田，冲积扇子和冰川的冰碛，偏移量地形提供限制为晚第四级滑动Xianshuihe差错的率。左侧面的罢工在东南片断上在西北片断上从17mm/a滑动Xianshuihe差错减少的率到9.3mm/a。认为Xianshuihe差错地区和它的邻近的块是一个地区性的构造系统，向量分析习惯于份量上分析纵的kinematical转变并且横过滑倒在地区以内以主要差错的kinematical参数在差错地区上划分。有的结果表演一分布式垂直以越过Gongga山区域弄短引起的6.1公里/年的率高举。把结果基于这些，我们建立了为Xianshuihe差错地区的东南的片断划分的slip的一个模型。

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简介：Tocomparetheeffectsofslow-releasenitrogenfertilizeratsixdifferentlevelsontheflagleafchlorophyllfluorescencecharacteristicsofsuperhybridrice,afieldfertilizationexperimentwasconductedwithsuperhybridriceYLiangyou1asatestmaterial.Thephotosyntheticelectrontransportrate(ETR),effectivequantumyield(EQY),photochemicalquenchingcoefficient(qP),andnon-photochemicalquenchingcoefficient(NPQ)offlagleavesweremeasuredattheinitialheading,fullheading,10dafterfullheadingand20dafterfullheadingstages.ResultsshowedthatthevaluesofETR,EQYandqPincreasedwithricedevelopmentfrominitialheadingto20dafterfullheading,whereastheNPQdecreased.Duringthemeasuredstages,ETR,EQYandqPincreasedinitiallyandthendecreasedasnitrogenapplicationamountincreased,buttheypeakedatdifferentnitrogenfertilizerlevels.ThemaximumETRandEQYvaluesappearedatthetreatmentof135kg/hm2N.Inconclusion,theoptimumnitrogenamountforchlorophyllfluorescencecharacteristicsofsuperhybridricewas135180kg/hm2.

简介：Inthispaper,accordingtotheresultsofthesatelliteimageryinterpretationandfieldinvestigation,westudytheactivefeaturesandthelatestactivetimesoftheChuxiong-Nanhuafault,theQuaternarybasinsformationmechanism,andtherelationshipbetweenthefaultandthe1680ChuxiongMs6%earthquake.SeveralQuaternaryprofilesatLvhe,NanhuarevealthatthefaulthasoffsetthelatePleistocenedepositsoftheT2andT3terracesofLongchuanriver,indicatingthatthefaultwasobviouslyactiveinlateQuaternary,TheChuxiong-NanhuafaulthasbeendominatedbydextralstrikeslipmotioninthelateQuaternary,withanaveragerateof1.6-2.Omm/a.SeveralpullapartQuaternarybasinsofChuxiong,Nanhua,andZiwuetc.havedevelopedalongthefault.The1680ChuxiongMs6%earthquakeandseveralmoderateearthquakeshaveoccurrednearthefault.TheChuxiong-Nanhuafaultaretheseismogenicstructureofthoseearthquakes,thelatestfaultmovementwasinthelate-Pleistocene,andeventheHolocene.Inlargearea,theChuxiong-NanhuafaultandtheeasternQujiangfaultandtheShipingfaultcomposedasetofNW-trendingobliqueorientationactivefaults,andthemotioncharacteristicsareallmainlydextralstrikeslip.Themotioncharacteristics,liketheredriverfaultoftheSichuan-YunnanRhombicBlocksouthwesternboundary,areconcernedwiththeescapingmovementoftheSichuan-YunnanRhombicBlock.

简介："Edie’sAvalanche:Snowedup"isapreviouslyunpublishedshortstoryofRichardJefferies’,ithasbeenstudiedfromdifferentapproaches.Thispaperdiscussesthechangingpositionandloveoftheprotagonistfromfeministapproach.

简介：Asuiteof1.84–1.92Gametamaficdykeswithintheparagneisssuite（khondalite）oftheQuanjimassifinNWChina,hasbeenchoseninthisstudyforfurtherunderstandingthetectonicevolutionandpossiblelinkstotheglobalColumbiasupercontinent.Occurrenceandfieldrelationssuggestthattheywereformedcoevallywithapreviousstudied1.83–1.85Gametamaficdykeswarms.Whole-rockmajorandtraceelementalgeochemistrysuggestsprecursormagmaoftheamphibolitesbeinggeneratedfromavolcanicarc-relatedtectonicsettingratherthanaback-arcenvironmentwherethemetamaficdykeswarmswereemplaced.ThemetamaficdykesshowenrichmentofLREEandstronglynegativeanomaliesforTa-Nb,Zr-HfandTi,havehighSiO2（49.3wt.%–52.5wt.%）butlowMgO（6.40wt.%–7.76wt.%）contentsandMg#（Mg#=[100×（MgO/40.3）]/[MgO/40.3+FeO/71.8]）values（45.7–52.1）,suggestingevolvedprecursormagma.ThehighvaluesofLa/Ta（22.2–42.8）andLa/Nb（1.71–2.47）,mildlynegativeεNd（t）values（-2.51–0.15）,withdepletedmantlemodelages（TDM）of2.45–2.84Ga,suggestthattheirprecursormagmaswerepossiblyderivedfromasubduction-relatedfluidmetasomatizedArcheansub-continentallithosphericmantle.Thisstudyprovidesfurtherevidenceforoceanicplatesubductionprevailingbeforeoraround1.85Ga,whichconfirmsaprolongedsubduction-accretion-collisionhistoryintheNWChinawhichispossiblylinkedtotheassemblyoftheColumbiasupercontinent.

简介：ZooplanktonsurveyswerecarriedoutonNovember2-3andDecember8-10,2001at12stationsintheNanWanBayofTaiwan,China.Altogether92quantitativezooplanktonsampleswerecollectedfromsubsurfacewaterandbottomwaterlayerswithtwoconicalplanktonnets(180cminlength,45cminopeningdiameter,333μmand200μminmeshsize).Atotalof31speciesofSiphonophoreswereidentified,amongthem7speciesarenewrecordsinthewatersaroundTaiwanIsland,ofwhichRocaceacymbiformisisanewrecordinChina.DominatedbyChelophyesappendiculata,Bassiabassensis,Diphyesbojani,Diphyesdispar,AbylopsiseschscholtziandChelophyescontorta,thesespeciesaccountedforover76%and63%ofthetotalabundanceinNovemberandDecember.ThespeciesnumberandSiphonophoresabundanceinDecember(25species,1.99inds/m3)weremorethanthoseinNovember(19species,0.438inds/m3),andtheyweremoreinthesurfacewaterlayerthaninthebottomlayeratmostsamplingstations.Inearlywinter,theoffshorehighsalinitywatermasswasamainfactorinfluencingthedistribution.ThesamplingefficiencyfortwoplanktonnetsisdiscussedandtheseasonalvariationofspeciesnumberandabundanceintheNanWanBayiscomparedwiththatintheneighboringwaters.

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简介：TheNeotethysplaysanimportantroleinshapingtheGangdesemagmaticbelt,southernTibet.However,theinitialtimeofspreadingandsubductionoftheNeotethysremainscontentious.Inthisstudy,asuiteoflateTriassiccumulatehornblendegabbrowasidentifiedinthesouthernmarginoftheGangdesemagmaticbelt.Thegabbroexhibitscumulatestructure,withhornblendeandplagioclaseastheprimarymineralphases.Isotopicdataindicateahydrousmagmasourcederivedfromadepletedmantlewedgethathasbeenmodifiedbyslabdehydration.Geochemicaldiscriminationssuggestthatthegabbrowasformedinanintraoceanicarcsetting,withcrystallizationagesofca.220-213Ma.Hornblende,hornblendelagioclaseandilmenitethermometersrevealthatthecrystallizationtemperatureof900-750°Cforthegabbro.Hornblendeandhornblende-plagioclasegeobarometersyieldanemplacementdepthatca.14.5-19.5km.ThisgabbroconstitutesalineofevidenceforanintraoceanicarcmagmatismthatiscoevalwiththecounterpartsinthesouthernTurkey,revealinganintraoceanicsubductionsystemwithintheNeotethysfromwesttoeastintheLateTriassicandthattheoceanizationoftheNeotethyswasmuchearlierthanpreviousexpectation.

简介：AnalluvialbajadahasbeenrecognizedalongapartoftheactiveNarmada-SonFault(NSF)andconfinedbytheKarjanRiverontheeasternsideandbytheMadhumatiRiveronwesternside.Thebajadasequenceexposedalongtheincisedcliffsofvariousnorthflowingparallelstreamshasbeenstudiedintheirproximal,medialanddistalpart.Thesedimentsarecharacterizedonthebasisofgrainsize,fabric,sedimentarystructures,bedgeometryandsorting,andlithologspreparedfromthemappedcliffsections.Detailedstudyofsedimentarycharacteristics,lithofaciesanalysisandfaciesassociationsindicatethatsedimentsaremainlyofthreetypes-sedimentsthatweredepositedbydebrisflowsandsedimentgravityflows,andasextensivebardeposits.Threemajoraggredationalsequencesarerecognized.Eachsequenceiscomposedofcoarsening-upwardsequenceofproximalfaciesoverlainbyfining-upwardsequenceofdistalfacies.CoarseningupwardsequencerecordperiodsoftectonicactivityrelatedtoupliftalongtheNSFandfanprogradation,whereasfining-upwardsequenceresultsfromtectonicquiescenceperiods.Thepresenceofrhizocretions,calciumcarbonatenodulesandcalcitesheetswithinthebasaldebrisflowandsedimentgravityflowindicatesemi-aridclimate,whereastheformationofpedoginizedpaleosolindicaterelativelywetterclimateprevailinginthestudyarea.TectonicactivityalongtheNSFhasplayeddominantrolebycontrollingthegeometryandvolumeofbajadasediments.Climateisfoundtoberesponsibleforcompositionalandtemporaldistributionofbajadasediments.OSLdatingsuggeststhatthebajadasedimentsweredepositedduringthelaterpartoflatePleistocene.TheincisionofthesedimentsisattributedtoupliftduetoinversionofthelowerNarmadabasinduringtheearlyHolocene.