简介:目的:在NAFLD动物模型建造过程中,对其实施亚低温状态5周游泳运动联合干预,比对研究各组别鼠肝组织病理切片、血清脂肪代谢指标、鼠肝组织氧化应激指标和HSP70mRNA表达量及其HSP70生成量变化,旨在实验研究改善NAFLD的机制。方法:60只SD大鼠随机分为对照组(C)、高脂组(F)、常温游泳高脂组(TS)、常温浸泡高脂组(TI)、亚低温游泳高脂组(HS)和亚低温浸泡高脂组(HI),每组10只。建造NAFLD动物模型的过程中,给予相应高脂分组预定干预。5周后宰杀SD大鼠,分别制备鼠肝组织病理切片、测试相关指标和采用固相夹心法酶联免疫吸附实验(ELISA)检测肝脏组织HSP70含量、Real-TimePCR相对定量分析测试肝组织HSP70mRNA。结果:肝组织病理学切片HE染色显示:HS相比TS肝小叶结构更清晰,脂滴空泡视野数目显著性减少;HS组血清学脂肪代谢指标:TG、TC、FFA相比F组有非常显著性降低;LDL相比F组有显著性降低;HDL相比F组降低,但是没有显著性差异;HS组肝组织氧化应激指标:MDA相比F组有非常显著性降低;GSH、SOD相比F组有非常显著性升高;HS组的肝组织HSP70同对照组C、F组比较呈升高,有非常显著性差异(P〈0.01);HS组的肝组织HSP70RNAReal-TimePCR表达量同对照组C、F组比较,均呈升高变化,有非常显著性差异(P〈0.01)。结论:在SD大鼠NAFLD模型建造过程中,实施亚低温状态下联合有氧运动干预措施,可以诱导NAFLD肝细胞生成大量应激蛋白参与并加速脂质代谢、参与增强NAFLD肝细胞抗氧化应激能力的环节从而延缓NAFLD的发生与发展。
简介:长铁杆通常指5号以上的2、3、4号铁杆,5号、6号为中长铁杆。长铁杆由于其杆面相对陡立,角度较小,所以不好掌握。一般的业余球手会用5号、7号球道木杆代替长铁杆的使用。
简介:Purpose:ThepurposeofthisquantitativereviewwastosummarizethestateofElliot’sHierarchicalModelofApproachandAvoidanceMotivation,specificallytheantecedentsofthe2×2achievementgoalsinthesport,physicalactivity,andphysicaleducationliterature.Inaddition,theintercorrelationsamongstthe2×2goalswerealsoexamined.Methods:Asystematicreviewoftheliteraturewasconducted.Meta-analyticprocedureswereusedwiththemeanweightedsamplecorrelation(rw)astheeffectsizemetric.TheantecedentswerecodedbyElliot’s(1999)antecedentcategories.Anumberofmoderatorswerecodedapriori.Results:Basedonafixedeffectsmodelfrom47publishedstudies(totaluniquen=15,413)thatmetinclusioncriteria,the2×2achievementgoalsweresignificantlycorrelatedamongsteachotherrangingfromsmalltomediumtolargeinmeaningfulness.Concerningtheantecedents,overalltheyweretheoreticallycorrectinassociations,butonlyafewoftherelationshipsweremediuminmeaningfulness.Mostrelationshipsweresmallinmeaningfulness.Heterogeneitywaspresentfortheinterrcorrelationandantecedentanalyses.Conclusion:FutureresearchisencouragedtogrowandenrichtheunderstandingofachievementgoalswithinElliot’scompleteHierarchicalModelofApproachandAvoidanceMotivationtoincludebothantecedentsandoutcomessimultaneouslytoimproveupontheunderstandingofachievementmotivationinsport,exercise,andphysicalactivitysettings.