简介:Inthisstudy,Ifocusedonfindingameanofprotectingagainsthearingloss.Byinfusingthecochleawiththeneurotrophinfactor,NT-3aloneorcombinedtreatmentwithMK801,aNMDAreceptorantagonistIfoundhearinglosswasattenuatedandspiralganglionneuronlosswasnearlytotallyprotectedindicatingthattheimportanceofthecombinedtreatmentofNT-3andNMDAreceptorantagonistsinthetreatmentofhearingdisorders.
简介:Thewaltzingguineapigmaybeagoodmodeltoinvestigateifgeneticfactorcanchangethesensitivityinnoise-inducedhearingloss.Atotalof34waltzigguineapigswerestudiedandwefoundthatthereisnoanysignificantincreasedsensitivitytonoisetraumaiftheage-inducedhearinglosswasconsideredinwaltz-ingguineapig.