简介：Immunecheckpointinhibitorsareincreasinglydrawingmuchattentioninthetherapeuticdevelopmentforcancertreatment.However,manycancerpatientsdonotrespondtotreatmentswithimmunecheckpointinhibitors,partlybecauseofthelackoftumor-infiltratingeffectorTcells.CancervaccinesmayprimepatientsfortreatmentswithimmunecheckpointinhibitorsbyinducingeffectorT-cellinfiltrationintothetumorsandimmunecheckpointsignals.Thecombinationofcancervaccineandanimmunecheckpointinhibitormayfunctionsynergisticallytoinducemoreeffectiveantitumorimmuneresponses,andclinicaltrialstotestthecombinationarecurrentlyongoing.
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