简介:Theclinicaleffectofacupunctureplusqigongonulcerativecolonitiswasanalyzedin113cases.Theywererandomlydividedintoelectroacupunctureplusqigonggroup(treatmentgroup,inshort),acupmoxigroupandqigonggroups.Theresultsshowedthatthecureratewas77%inthetreatmentgroup,57%intheacupmoxigroupand53%intheqigonggroup.Achisquaretestshowedasignificantdifference(P<0.01),indicatingthatelectroacupunctureplusqigonghadamarkedcurativeeffectandsuggestingthatearlytreatmentcanproduceasatisfactoryeffect.
简介:76patientsofimpotencewererandomlydividedintotwogroups.Of28casesinacupuncturegroup,18werecured,5effectiveand5ineffective.Of48casesinacupunctureplusacu-point-injectiongroup,41werecured,5effectiveand2ineffective.Thecurativeeffectintheacupunc-tureplusacupoint-injeetiongroupwassuperiortothatintheacupuncturegroup(P<0.01).
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简介:AbstractBackground:With the wide application of endoscopic submucosal dissection (ESD) for early gastric neoplasms, metachronous gastric neoplasms (MGN) have gradually become a concern. This study aimed to analyze the characteristics of MGN and evaluate the treatment and follow-up outcomes of MGN patients.Methods:A total of 814 patients were retrospectively enrolled. All these patients were treated by ESD for early gastric cancer or gastric dysplasia between November 2006 and September 2019 at The First Medical Center of Chinese People’s Liberation Army General Hospital. The risk factors for MGN were analyzed using Cox hazard proportional model. Moreover, the cumulative incidence, the correlation of initial lesions and MGN lesions, and the treatment and follow-up outcomes of MGN patients were analyzed.Results:A total of 4.5% (37/814) of patients had MGN after curative ESD. The 3-, 5-, and 7-year cumulative incidences of MGN were 3.5%, 5.1%, and 6.9%, respectively, and ultimately reaching a plateau of 11.3% at 99 months after ESD. There was no significant correlation between initial lesions and MGN lesions in terms of gross type (P = 0.178), location (long axis: P = 0.470; short axis: P = 0.125), and histological type (P = 0.832). Cox multivariable analysis found that initial multiplicity was the only independent risk factor of MGN (hazard ratio: 4.3, 95% confidence interval: 2.0-9.4, P < 0.001). Seventy-three percent of patients with MGN were treated by endoscopic resection. During follow-up, two patients with MGN died of gastric cancer with lymph node metastasis. The disease-specific survival rate was significantly lower in patients with MGN than that in patients without MGN (94.6% vs. 99.6%, P = 0.006).Conclusions:The MGN rate gradually increased with follow-up time within 99 months after curative gastric ESD. Thus, regular and long-term surveillance endoscopy may be helpful, especially for patients with initial multiple neoplasms.
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简介:Inthepresentpaper,theclinicalcurativeeffectsofcatgutembeddingtherapyandtraditionalacupuncturetherapyfortreatmentoflumbarmusclestrainwerecompared.Thesameacupointswereusedinbothgroups.Resultsshowedthattheeffectiverateswere100%and92.5%respectivelyin80casesofthecatgutembeddinggroupand40casesoftheacupuncturegroup.Therewasasignificantdifferencebetweenthetwogroups(P<0.005).Itindicatesthatthecatgutembed-dingtherapyisaneffectivemethodfortreatmentoflumbarmusclestrain.
简介:BACKGROUND:Conventionalmethods(suchasocclusiontherapy,finemanipulation,complementary,andalternativemedicine)takeeffectsslowly,aretimeandlaborconsuming,andhaveuncertaincurativeeffectsinthetreatmentofamblyopia.Perceptuallearning,anewmethodfortreatingamblyopia,improvestheabilitytoprocesssignalsfromthecerebralopticnervesystembyspecificvisualstimulationandvisuallearning,aswellasactivationofthevisualsignalpathwayutilizingbrainnervoussystemplasticity.OBJECTIVE:Thisstudyinvestigatedandevaluatedthecurativeeffectsofperceptuallearning,whichcandirectionallyincreasebrainplasticity,onthetreatmentofamblyopiainchildren.Therelationshipbetweencurativeeffectandtimewasalsoanalyzed.DESIGN:Aself-controlexperiment.SETTING:VisualScienceandOptometryCenter,People'sHospitalofGuangxiZhuangAutonomousRegion.PARTICIPANTS:Atotalof125amblyopicchildren(250amblyopiceyes),73males,52females,averaging(6±2)yearsofage,receivedtreatmentattheVisualScienceandOptometryCenter,People'sHospitalofGuangxiZhuangAutonomousRegionbetweenSeptember2006andFebruary2007andwererecruitedforthisstudy.Allchildrenpresentedwithnostructuraldiseaseoftheeyeballs.Writteninformedconsentfortherapeuticregimentswasobtainedfromeachchild'sparent.TheprotocolreceivedapprovalfromtheHospital'sEthicsCommittee.METHODS:Visualfunctionwastestedwithaperceptuallearningsystem(ResearchCenterforHumanHealthandDevelopmentofSunYat-senUniversity,NationalEngineeringTechniqueResearchCenterforMedicalCareImplement)forvisualnoise,positionnoise,contourdiscrimination,contrastsensitivity,gratingstereogram,andrandom-dotfusion.Thesetestshelpedtoevaluatetheefficiencyofvisualinformationprocessingofthesechildren,andtodeterminethedegreeofdefectsoftheopticnervecellsandtheconnectionsofvisualcorticalneurons.Accordingtoresultsofvisualfunct
简介:Fucoidan能通过有免疫力的激活治好锑敏感、锑抵抗的内脏的leishmaniasis。然而,位于这细胞的回答下面的发信号的事件仍然是uncharacterized。现在的学习表明fucoidan导致p38和ERK1/2和NF-κ的激活;在正常和利什曼原虫的BDNA绑定感染donovani的巨噬细胞由西方的弄污和electrophoretic活动性移动揭示了试金(EMSA)分别地。p38,ERK1/2或NF-κ的药理学抑制;B小径显著地稀释了导致fucoidan的支持inflammatorycytokine合成和可诱导的氮的氧化物synthase(iNOS)基因抄写,导致寄生虫清理的减小。为了译解,各种各样的蛋白质kinaseC(PKC)isoforms的调停fucoidan的寄生虫抑制,表示和功能的内在的机制被immunoblotting和酶活动试金评估。Fucoidan在PKC-α的表示和活动得到了增加;,在感染的巨噬细胞的-βI和-βIIisoforms。功能PKC-α击倒;并且-β;导致了p38和ERK1/2的downregulation,与IL-12和TNF-α的显著减小一起;在对待fucoidan的感染的巨噬细胞的生产。一起,这些结果建议fucoidan的药品效果被激活mitogen的蛋白质kinase(MAPK)的PKC依赖的激活调停/NF-κ;B小径,它最终导致氮的氧化物的生产(没有)并且解决疾病的支持inflammatorycytokines。
简介:Sixty-fivecasesofherpeszosterwererandomlydividedintotheHe-Nelasergroup(33cases)andpolyinosinicacidgroup(32cases).TypeJIHe-NelaseruniversaltreatmentapparatuswasusedtoirradiateinjuredcutaneousregionsandtoradiateHegu(LI4)andZusanli(ST36)pointswithphotoconductivefibersonceeverydayintheHe-Nelasergroup;2mlofpolyinosinicacidwasin-tramuscularlyinjectedonceeveryotherdayintheothergroup.Ofthe65cases63werecured,andthetwocaseswithsequelaofneuralgiawereallinthelattergroup.Painwasdisappearedandscabswereformedrespectivelyafter1.48and5.76daysoftreatmentwithHe-Nelasertherapy,andafter10.5and10.4dayswithpolyinosinicacidtreatment.Thedifferencesoftherapeuticeffectsbetweenthetwogroupswerenoticeablysignificant(P<0.01).
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简介:摘要:目的:探讨靶向+全脑治疗在肺腺癌EGFR敏感突变多发脑转移患者中的疗效与安全性。方法:选取2018年1月到2020年1月我院就诊的肺腺癌EGFR敏感突变多发脑转移患者共70例作为研究对象,随机分为两组各