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  • 简介:AbstractBackground:Reviving patients with prolonged disorders of consciousness (DOCs) has always been focused and challenging in medical research. Owing to the limited effectiveness of available medicine, recent research has increasingly turned towards neuromodulatory therapies, involving the stimulation of neural circuits. We summarised the progression of research regarding neuromodulatory therapies in the field of DOCs, compared the differences among different studies, in an attempt to explore optimal stimulation patterns and parameters, and analyzed the major limitations of the relevant studies to facilitate future research.Methods:We performed a search in the PubMed database, using the concepts of DOCs and neuromodulation. Inclusion criteria were: articles in English, published after 2002, and reporting clinical trials of neuromodulatory therapies in human patients with DOCs.Results:Overall, 187 published articles met the search criteria, and 60 articles met the inclusion criteria. There are differences among these studies regarding the clinical efficacies of neurostimulation techniques for patients with DOCs, and large-sample studies are still lacking.Conclusions:Neuromodulatory techniques were used as trial therapies for DOCs wherein their curative effects were controversial. The difficulties in detecting residual consciousness, the confounding effect between the natural course of the disease and therapeutic effect, and the heterogeneity across patients are the major limitations. Large-sample, well-designed studies, and innovations for both treatment and assessment are anticipated in future research.

  • 标签: Disorders of consciousness Neuromodulation Therapy
  • 简介:Eveninclasseswhichstressoralpractice,theexplicitteachingofgrammarstillhasaroletoplay.EvelynDomanexplainswhyandpresentssomepracticalactivitieswhichintegrategrammarteachingwithcommunicativetasksinthegrammaticalconsciousness-raisingapproach.IntroductionTheroleofgrammarintheforeignlanguageclassroomhasbeendebatedbothlongandhard.Theoriesaboutteachinggrammarhavecoveredallrangesofthespectrum,goingfromplayingamajorroletobasicallyplayingnoroleatall.Today,CommunicativeLanguageTeaching(CLT)istheforerunnerintheTESL/TEFLcommunity.Yet,evenwithintheCLTframework,thecontroversyovertheteachingofgrammarcontinues.Manypeoplestillassertthatgrammarbegivenitsplace.Itooamamongthesepeople,especiallyinEFLenvironments,suchasinmypreviousteachingsituationsinSouthKorea.

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  • 简介:【摘要】随着社会经济发展,基础设施建设成为普遍性需求,因此也为农民工提供大量岗位,但也出现了大量农民工维权案件,这是否和农名工法律意识薄弱有关,是否是农名工打工现状的普遍现象,本文对此开展了调查研究。

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