简介：Recentdevelopmentsinthenovelimagingtechnologyofcardiaccomputedtomography(CT)notonlypermitdetailedassessmentofcardiacanatomybutalsoprovideinsightintocardiovascularphysiology.Foremost,coronaryCTangiography(CCTA)enablesdirectnoninvasiveexaminationofbothcoronaryarterystenosesandatheroscleroticplaquecharacteristics.CalculationofcomputationalfluiddynamicsbycardiacCTallowsthenoninvasiveestimationoffractionalflowreserve,whichincreasesthediagnosticaccuracyfordetectionofhemodynamicallysignificantcoronaryarterydisease.Inaddition,acombinationofmyocardialCTperfusionandCCTAcanprovidesimultaneousanatomicalandfunctionalassessmentofcoronaryarterydisease.Finally,detailedanatomicalevaluationofatrial,ventricular,andvalvularanatomyprovidesdiagnosticinformationandguidanceforproceduralplanning,suchasfortranscatheteraorticvalvereplacement.TheclinicalapplicationsofcardiacCTwillbeextendedwiththedevelopmentofthesenovelmodalities.

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简介：DearEditor,Vogt-Koyanagi-Harada(VKH)diseaseisacell-mediatedautoimmunesyndromedirectedagainstmelanocytes.Itisconsideredamultisystemdisordercharacterizedbygranulomatouspanuveitisoftenassociatedwithneurologicandcutaneousmanifestations.Thechoroidisthemainsiteof

简介：Invasivefractionalflowreserve(FFR)measurementiscurrentlythegoldstandardforcoronaryintervention.FFRmeasurementbycoronarycomputedtomographyangiography(FFRCT)isanovelandpromisingimagingtechnologythatpermitsnoninvasiveassessmentofphysiologicallysignificantcoronarylesions.FFRCTiscapableofcombiningtheanatomicinformationprovidedbycoronarycomputedtomographyangiographywithcomputationalfluiddynamicstocomputeFFR.Todate,severalstudieshavereportedthediagnosticperformanceofFFRCTcomparedwithinvasiveFFRmeasurementasthereferencestandard.FurtherstudiesarenowbeingimplementedtodeterminetheclinicalfeasibilityandeconomicimplicationsofFFRCTtechniques.ThisarticleprovidesanoverviewanddiscussestheavailableevidenceaswellaspotentialfuturedirectionsofFFRCT.

简介：AIM:Todescribetheinvolutionpatternsofvesselgrowthofretinathroughfluoresceinangiography(FA)ofchildren,whohadbeenundertreatmentupto1ypreviouslyintravitrealranibizumab(IVR)asmonotherapyforretinopathyofprematurity(ROP).METHODS:Thisisaretrospectivestudy.ThemedicalinformationandFAof17children(34eyes)whoseareaofavascularretinafromtheoraserratawasmorethantwodiscdiameters(DD)wereanalyzed.RESULTS:Among34eyes,allwerethepresenceoffinger-shapedvesselsandarteriolar-venularshunts(100%,34/34eyes).Popcornabnormalitieswerefoundinmostoftheeyes(94.1%,32/34eyes).Furthermore,inmanycases(23.5%,8/34eyes),therewereleakagepersistingintheregionofthejunctionbetweenavascularandvascularretina.Incontrast,just2eyes(5.9%)showeddamageofretinalcapillarybedand3eyes(8.8%)showedlargeareaofretinalpigmentepithelium(RPE)atrophy.CONCLUSION:AlthoughIVRcanbeveryeffectiveinROP,weshouldremaincautiousasinfantsmayremainavascularperipheralretinasandabnormalvessel.FAallowsaccuratevisualizationofvesselabnormalitiesineyeswithROP,whichwillbehelpfultoaffectassessmentofdiseaseactivityandtherapeuticeffect.

简介：AbstractBackground:Diabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM.Methods:This study recruited consecutive patients who underwent coronary computed tomography (CT) angiography (CCTA) between October 2016 and November 2017. Personal information including conventional cardiovascular risk factors was collected. Plaque phenotypes were automatically calculated for volume of different component. The volume of different plaque was compared between DM patients and those without DM.Results:Among 6381 patients, 931 (14.59%) were diagnosed with DM. The prevalence of plaque in DM subjects was higher compared with nondiabetic group significantly (48.34% vs. 33.01%, χ2 = 81.84, P < 0.001). DM was a significant risk factor for the prevalence of plaque in a multivariate model (odds ratio [OR] = 1.465, 95% CI: 1.258-1.706, P < 0.001). The volume of total plaque and any plaque subtypes in the DM subjects was greater than those in nondiabetic patients significantly (P < 0.001).Conclusion:The coronary artery atherosclerotic plaques were significantly higher in diabetic patients than those in non-diabetic patients.

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简介：AbstractBackground:Indocyanine green video angiography (ICG-VA) is a safe and effective instrument to assess changes in cerebral blood flow during cerebrovascular surgery. After ICG-VA, FLOW 800 provides a color-coded map to directly observe the dynamic distribution of blood flow and to calculate semiquantitative blood flow parameters later. The purpose of our study is to assess whether FLOW 800 is useful for surgery of complex intracranial aneurysms and to provide reliable evidence for intraoperative decision-making.Methods:We retrospectively reviewed patients with complex aneurysms that underwent microsurgical and intraoperative evaluation of ICG-VA and FLOW 800 color-coded maps from February 2019 to May 2020. FLOW 800 data were correlated with patient characteristics, clinical outcomes, and intraoperative decision-making.Results:The study included 32 patients with 42 complex aneurysms. All patients underwent ICG-VA FLOW 800 data provided semiquantitative data regarding localization, flow status in major feeding arteries; color maps confirmed relative adequate flow in parent, branching, and bypass vessels.Conclusions:FLOW 800 is a useful supplement to ICG-VA for intraoperative cerebral blood flow assessment. ICG-VA and FLOW 800 can help to determine the blood flow status of the parent artery after aneurysm clipping and the bypass vessels after aneurysm bypass surgery.

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简介：AIMTo比较在两个的灌注由使用光连贯断层摄影术angiography(OCTA)与正常控制组一起单方的自发的有斑点的洞(IMH)看的眼的神经头(ONH)并且调查它的correlationship，有斑点的血perfusion.METHODSWe表现了包括了19个病人与的未来、代表性的研究完整厚度单方IMH和24匹配年龄、匹配性的控制。所有参加者收到了OCTA测试。ONH灌注被peripapillary和全部的区域在脸(peripapillary和眼的圆盘的和)评估。在ONH和parafovea之间的潜在的correlationship被暗示。所有数据用介绍的ONH的nonparametrictest.RESULTSThe平均数值被执行那正常控制>IMH>未受影响的眼睛。一个统计变化在这个区域在三个组之间被发现时间(P=0.007)。容器密度著名地在层上减少了表面，深并且在IMH的parafovea区域的脉络膜组。关联词系数在脸和深视网膜完全分别地显示出那：r=0.528，peripapillary和深视网膜：r=0.525，在脸和choriocapillaries整个：r=0.569，peripapillary和choriocapillaries：r=0.504.CONCLUSIONOur学习在IMH眼睛在IMH病人和ONH的容器密度的两只眼睛表明减少的ONH容器密度断然在parafoveal与毛状的视网膜和choriocapillary被相关。容器密度的减小可以在IMH眼睛显示hypoperfusion。

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