简介：InthelaterpartoftheTang,localinterestsgroupswhoserepresentativeswereprovincialgovernorszealouslysupportedcarvingFangshanStoneSutrasandotherBuddhistaffairs.CommandingofficersofsubordinatecountiesinLulongprovincechargedadministrative,militaryandsupervisingaffairs,andhadrelativeorfake-relativelinkswiththeirprovincialgovernorsorbodyguards.Themilitarypowerofsubordinatecountiesalsoplayedanimportantroleinthetransformationofpoliticalconditions.CommandingofficersofsubordinatecountiesoftentookpartincarvingFangshanStoneSutras,too.TheyalsocarvedStoneSutraswithbodyguardsfortheirprovincialgovernors.ThiswasasignificantwayofcondensingYouzhoubloc.

简介：ObjectiveTostudytheinfluenceofJiangTangFangLongformulaoninsulinproductionandfunctioninananimalmodelofdiabetichearingloss.MethodsWistarrats(n=60)wererandomlydividedinto6groups(10ineach)toreceivenotreatment(thenormalcontrol,GroupA),ortoreceiveintra-peritoneal55mg/kgstreptozotocinwith(GroupsC,DandE)orwithout(GroupB)subsequentJiangTangFangLongformulatreatmentatvariousdosesorYuLongWantreatment(GroupF).After60days,fastingbloodglucose(FBG),bodyweight(BW)andfastinginsulin(FINS)wererecordedandtheHOMA-IRandHOMA-βcalcu-lated.Insulinexpressioninpancreatictissueswasmeasuredbyradioimmunoassay.ResultsComparedwithanimalsthatreceivedstreptozotocinwithoutrescuetreatment(GroupB),animalsthatreceivedhigherdosesofJiangTangFangLongformula(GroupsDandE)showedimprovedindicesofdiabetesmanifestation(P<0.05)andimprovedHOMA-β(P<0.05)inadose-dependentmanner,aswellasimprovedinsulinexpressioninpancreaticislets(P<0.05).ThedifferencebetweenlowdoseJiangTangFangLongformulatreatment(GroupC)andGroupBwasnotsignificant(P>0.05).ConclusionOurresultssuggestthatJiangTangFangLongformulamayimprovepancreaticβ-cellsfunctionwhichmayexplainitsefficacyintreatingdiabetichearingloss.