简介:Somaticstemcells(SSCs),beingessentialinmaintaininghomeostasisofnormaltissue,replenishdyingcellsandregeneratedamagedtissuesfororganism.Ontheotherhand,withtheself-renewedability,SSCsareidealcellulartargetstobeacquiredinmultiplemutationstransformingSSCstocancerstemcells(CSCs)whichcausemalignanciesandevenrecurrenceaftercancertreatmentifCSCsfailtobeeradicated(1).OneyearafterDrs.JohnB.GurdonandShinyaYamanakasharedthe2012NobelPrizeinPhysiologyorMedicinefortheirdiscoverythatmaturecellscanbereprogrammedtobecome