简介：Acyano-substituteddiarylethlenederivativeaggregation-inducedemission(AIE)dyewithtwoaminoend-groupsand4,4'-(hexafluoroisopropylidene)diphthalicanhydridewerefacilelyincorporatedintoredfluorescentorganicnanoparticles(FONs)viaroomtemperatureanhydridering-openingpolymerizationunderanairatmosphere.TheseobtainedRO-HFDAFONswerecharacterizedbyaseriesoftechniquesincludinggelpermeationchromatography,Fouriertransforminfraredspectroscopy,sizedistributionandzetapotentialmeasurements,UV-Visabsorptionspectrum,fluorescentspectroscopyandtransmissionelectronmicroscopy.BiocompatibilityevaluationandcelluptakebehaviorofRO-HFDAFONswerefurtherinvestigatedtoexploretheirpotentialbiomedicalapplication.WedemonstratedthatsuchFONsshowedhighwaterdispersibility,stableuniformsphericalmorphology(150-200nm),broadexcitationband(350-605nm),intenseredfluorescence(627nm)andexcellentbiocompatibility,makingthempromisingforcellimagingapplications.

简介：变形癌症房间的俘获和察觉为恶意的瘤的诊断和治疗是关键的。这里，我们报导folic酸(FA)的使用poly修改了electrospun(乙烯基白酒)(PVA)为癌症房间俘获应用的/polyethyleneimine(PEI)nanofibers。由glutaraldehyde蒸汽的ElectrospunPVA/PEInanofiberscrosslinked与FA被修改经由一poly(乙烯乙二醇)(木钉)分隔符，由纤维表面PEI胺的acetylation列在后面。形成的修改FA的nanofibers很好被描绘。electrospunPVA/PEInanofibers的形态学尽管有表面修正光滑、一致。另外，修改FA的nanofibers显示由溶血证实了的好hemocompatibility试金。重要地，发达修改FA的nanofibers能明确地捕获癌症房间overexpressingFA受体，它被数试金和质的共焦的显微镜学分析的量的房间验证。发达修改FA的PVA/PEInanofibers可以被用于为癌症诊断应用程序捕获传播肿瘤房间。

简介：Twograftingmethods,i.e.solutiongraftingandpre-adsorbing,areintroducedtocovalentlyimmobilizehydrophilicpolymersonsegmentedpolyurethane(SPU)tomodifyitshydrophilicityandtoimproveitscellcompatibility.Solutiongraftingresultsinhigherdegreeofgraftingandroughersurfacemorphology.Cellcultureevaluationdemonstratesthatthemodifiedmembranesthusobtainedaredisadvantageoustotheendothelialcell(ECs)growthprobablybecausethehydrophilicgroupsonthesurfaceareover-crowded.However,pre-absorbinggraftinggenerateslowerdegreeofgrafting,whichisdetectedandconfirmedbyATR-FTIRspectraandwatercontactangle.Scanningelectronmicroscopic(SEM)measurementshowsthatthelattermethodproducesaplaneandsmoothmorphology,whichissimilartotheSPUcontrolsamplecontrolled.Whengraftingwithlowermonomerconcentration,ECscouldgrowonSPU-g-PHEA[poly(2-hydroxyethylacrylate)],SPU-g-PAAm(polyacrylamide),SPU-g-PDMA[poly(2-(dimethylamino)ethylmethacrylate)]orquaternizedSPU-g-PDMAsurfacewithelongatedcellshapes.Hence,thecellcompatibilityofSPUisimprovedandausefulmethodtoconstructacellcompatiblelayeronthepolymersurfacehasbeendeveloped.``

简介：PolysaccharidecoatedPLAnanoparticlesbearingaldehydegroupswerepreparedbydialysisofDMSOsolutionofcholesterolhydrophobic-modifieddextranpolyaldehydeandPLAagainstwater.Theaveragediameterofthenanoparticleswasabout160nm,andthesizedistributionwasnearlyhomogenous.ThenanoparticleswerefunctionalizedsimultaneouslywithCD71andEGFRantibodythroughtheSchiff'sbasereaction,andthenradiolabeledwith~(99m)Tc.Afterperfusedtheradiolabelednanoparticlesintotumor-bearing...

简介：Conventionalorganicsolarcell’s(OSC)architectures,includingrigidtransparentsubstrate(Glass),conductiveelectrode(Indiumtinoxide,ITO)andsmallworkingareas,arewidelyutilizedinorganicphotovoltaicfields.However,suchastructureaswellasconventionalspin-coatingmethodobviouslyrestricttheirindustrialapplication.Inthisarticle,wereportthedepositionofsilvernanowires(AgNWs)ontheflexiblesubstratebyslot-dieprinting.TheobtainedAgNWsfilmsexhibitedahightransmittanceandalowresistance,andwerefurtherusedasthetransparentconductiveelectrodeofOSCs.Atypicalconjugatedpolymer,poly[(2,5-bis(2-hexyldecyloxy)phenylene)-alt-(5,6-difluoro-4,7-di(thiophen-2-yl)benzo[c][1,2,5]thiadiazole)](PPDT2FBT),wasusedastheactivematerialtofabricatelarge-area(7cm~2)solarcellsbyaslot-diecoatingprocess.Thepowerconversionefficiency(PCE)couldreach1.87%initiallyandfurtherincreasedto3.04%bythermalannealing.ComparedtotheperformanceofreferencecellonITOsubstrate,theresultindicatedthattheAgNWscouldbedevelopedasanalternativesubstituteofconductiveelectrodetofabricatethelarge-areaflexibleOSCsbyroll-to-rollprinting.