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  • 简介:INTRODUCTIONCalciumphosphatecements(CPC)overcomethepracticaldisadvantagesofblocksorgranuleslcanbehandledasapasteandsitinsitu.TheirstructureandcompositionclosetothatofHAPmakethembiocompatiblematerials.2Theconventionalcalciumphosphatecementhadsomeproblemssuchaslongsettingtime(30~60min)andlowcompressivestrength,etc.Inoursystem,anα-TCP/TTCPpowdermixturewasmixedwithwatercontainingcitricacidtocontrolthesettingtimeandcompressivestrength.Inthispaper,theeffectsofvariousconcentrationcitricacidsolutionsonthepropertiesofthecementarereported.

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  • 简介:Objective:AnovelPVA-CaAlgcompositematerialbypolyvinylalcohol(PVA)andsodiumalginate(SA)wasfabricatedtoinvestigatethefeasibilityservingasascaffoldfortissueengineeringandtofindoutthemostidealproportionaccordingtotheirproperties.Methods:Film,graininessandspongescaffoldsofPVA-CaAlgwerefabricatedbythreedifferentmethods.Watercontentandswellingratioweretested.SEMwasusedtoobservetheconfigurationofthecrosssection.Results:DifferentproportionalscaffoldscouldbeobtainedwithdifferentPVAmolecularweight,alcoholysisdegreeanddifferentSAdosages.Thewatercontentofdifferentscaffoldsrangedfrom48%to93%andshoweddifferentinnerconfigurationwithswellingratiobetween120%and470%.SEMprovedthatdifferentcompositematerialshaddifferentporousstructures.Conclusion:AscaffoldfortissueengineeringwithhighwatercontentandproperswellingratiocanbefabricatedusingPVAandSA.Theporousstructureshowspotentialintissueengineeringandcellculture.

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