学科分类
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4 个结果
  • 简介:CardiovascularimmunologyresearchinWuhanUnionHospitalbeganin1991.Anti-heartantibodiesindilatedcardiomyopathyandacuteviralmyocarditisbegantobereportedfrom1993.ItwasfoundthatanewautoantibodyagainstL-typecalciumchannelresultsinventriculartachycardiaandsuddendeathinpatientswithdilatedcardiomyopathy.ThroughtheInterventionStudyofDiltiazeminDilatedCardiomyopathy,diltiazemwasverifiedtoreducemortalityandthechronicheartfailurehospitalizationratesignificantlyinpatientswithdilatedcardiomyopathy.TheautoantibodiesagainstangiotensinIIreceptortype1andα1-adrenoceptorwereassociatedwiththeincreasedrecurrenceofanddeathfromstrokeinhypertensivepatients.Throughmanyclinicalandexperimentalstudies,thefunctionalimbalanceofT-cellsubsetswassuggestedtomediatemyocardialinjuryandchronicheartfailure,whichprovidedanewtheoreticalbasisforimmunoregulationtherapyforheartfailure.Thefirstantihypertensivepolypeptidevaccine(ATRQβ-001)wasinvented.Inadditiontotheseachievements,therewillbemoreresearchoncardiovascularimmunologyinWuhanUnionHospitalinthefuture.

  • 标签: AUTOANTIBODY T cells hypertension DILATED CARDIOMYOPATHY
  • 简介:ObjectivesTotestthefeasibilityoftheuseofhighthoracicepiduralanesthesiaasasoleanestheticinpatientsundergoingoffpumpcoronaryarterybypasssurgery,avoidinggeneralanesthesia.MethodsBetweenOctober2002toApril2003,twentyfivecasesunderwentbeatingheartcoronaryarteryrevascularizationwithoutendotrachealgeneralanesthesia,usinghighthoracicepiduralanesthesiaandanalgesia.Allthepatientsunderwentepiduralcatheterizationontheeveningbeforethesurgery.ResuitsThepatientsinallreceived71grafts(singlen=11,doublen=5,triplen=6,quadruplen=3).Sixpatientsunderwentrepeatcoronaryarterybypass.Exceptonewasconvertedtogeneralanesthesiaandcardiopulmonarybypass,theotherpatientsunderwentoff-pumpcoronaryarterybypassgraftsurgery,2patientsunderwentgraftingvialeftthoracotomy(MIDCAB)andtherestthroughmidsternotomy.Therewasnomortality.Meanlengthofstayintheintensivecareunitwas16.2(4.2hoursandhospitalwas3.0(1.2days.ConclusionsOurexperienceconfirmsthefeasibilityofperformingmuhiplecoronaryarterybypassesinconsciouspatientswithoutendotrachealgeneralanesthesia.

  • 标签: 胸膜外麻醉 冠状动脉旁路抽吸术 心外科 血管成形术
  • 简介:据台湾媒体报道,台湾屏东县一位超级妈妈陈林面25年间竞接连生育了12个孩子,且无一例外都是千金。如今“十二金钗”都已长大,已经87岁高龄的她儿孙满堂,多的连自己都不清楚。

  • 标签: 专家 女儿 媒体报道 台湾地区