简介:摘要阴道毛滴虫病系由阴道毛滴虫所致的性传播感染,可同时累及生殖道及泌尿道,引起阴道炎、尿道炎、膀胱炎或无症状,常与细菌性阴道病、沙眼衣原体感染和淋病并存。阴道毛滴虫病可导致不良生殖健康结局。持续性阴道毛滴虫病已经在我国出现,并成为临床治疗的难点。根据临床表现和实验室检查如阴道分泌物悬液显微镜检查或核酸扩增等诊断。治疗方案包括甲硝唑2 g顿服或替硝唑2 g顿服,需要对患者的性伴同时治疗,对持续性阴道毛滴虫病需要应用高剂量或超高剂量替硝唑治疗。
简介:摘要目的探讨人类乳头病毒或者阴道毛滴虫与宫颈细胞学改变的相关性.方法收集本院8460例患者的宫颈脱落细胞及阴道分泌物标本.生理盐水悬滴法鉴定阴道毛滴虫,HCⅡ法鉴定人类乳头病毒,液基薄层细胞术鉴定宫颈细胞学改变.结果高危型HPV感染率(34.65%)远高于于阴道毛滴虫的感染率(2.98%)(P<0.001).HPV(OR50.716)、TV(OR3.258)单个感染或者HPV、TV(OR101.058)共同感染均与宫颈细胞学阳性改变有关.HPV感染导致的细胞学检测阳性主要集中在ASCUS36.43%(513/1408)、LSIL44.89%(632/1408)、HSIL13.85%(195/1408).而TV感染导致的细胞学检测阳性主要集中在ASCUS65.52%(38/58).结论HPV和TV感染均可以导致宫颈细胞学检查阳性,HPV比TV更容易导致宫颈细胞学检查阳性,且细胞学改变比TV较重.关键字阴道毛滴虫;人类乳头状瘤病毒;宫颈细胞学;薄层液基细胞术CorrelationstudyofHumanpapillomavirus、TrichomonasvaginalisandcervicalcytologyYaoFeng;ZhangYu-quan;LiHong-yu;ZhangJian-lin;YangYi-mei;Wangshan-shan;ChenCheng;ZhangJun-rongDeApbasrttrmacetntOobfjgeyctniaveecologyandobstetrics,Affiliatedhospitalofnantonguniversity,Nantong,226001TostudytherelativitybetweenHumanpapillomavirusandcervicalcytology,andtherelativitybetweenTrichomonasvaginaGlisandcervicalcytology.MethodsExfoliatedcellsincervixuteriandVaginalfluidof8460patientswerecollected.Trichomonasvaginaliswasdetectedbythehangingdropmethod.HumanpapillomaviruswasdetectedbyHybridcaptureⅡ.ExfoliatedcellsincervixuteriweredetectedbyThinprepcytolGogytest.ResultsInfectionrateofHumanpapillomavirus(34.65%)washigherthanthatofTrichomonasvaginalis(2.98%)(P<0.001).InfectionofHumanpapillomavirus(OR50.716)orTrichomonasvaginalis(OR3.258)alonecanbethereasonofpositivecervicalcytologydetection.AndInfectionoftwofactorstogether(OR101.058)also.36.43percentofthepositivecervicalcytologydetectionresultscausedbyinfectionofHumanpapillomaviruswasASCUS.44.89percentofthatwasLSIL.And13.85percentofthatwasHSIL.65.52percentofthepositivecervicalcytologydetectionresultscausedbyinfectionofTrichomonasvaginaliswasASCUS.ConclusionBecauseofinfectionofHumanpapillomavirusorTrichomonasvaginalis,theresultsofcerGvicalcytologydetectionwaspositive.ItiseasierforinfectionofHumanpapillomavirustobringaboutcervicalcytologydetectionpositivethanforinfecGtionofTrichomonasvaginalis.TheresultofcervicalcytologydetectionbecomingpositivecausedbyinfectionofHumanpapillomaviruswasmoreseriousthanthKaetybwyoirndfsectionofTrichomonasvaginalis.Humanpapillomavirus;Trichomonasvaginalis;cervicalcytology;Thinprepcytologytest中图分类号R373文献标识码B文章编号1008-6315(2015)10-0341-02