简介:AbstractChagas disease remains a serious problem for public health due to the high disease burden together with its global spreading patterns. However, current treatment and vector control are highly challenged by drug and insecticide resistance. Chemotherapy and vector control have been proved to be effective attempts to minimize the disease burden. Continued efforts are necessary to keep adapting the surveillance-response systems to the dynamic health systems. More attention and investments are needed to improve appropriate strategy and technology in different settings. This may be accomplished by creating effective risk early warning, addressing vulnerability and building resilience systems, implementing a vector surveillance system, as well as innovating research and technology.
简介:目的将观察在浆液嗜曙红血球cationic蛋白质(ECP)上联合传播艾灸和点注射的效果,类脂化合物peroxidase(LPO)和在有咳嗽变体气喘的病人的细胞的免疫。150个盒子全部的方法A满足了包括标准的人,被使随机化进三个组,50在每个组。传播艾灸和点注射在观察组被采用,在点注射组独自在传播艾灸组和点注射独自散布艾灸。然后,治疗学的功效在治疗的一堂功课以后被评估。结果恢复率和全部的有效的率在观察组分别地是50.0%和98.0%,对18.0%和86.0%在传播艾灸组织,14.0%和82.0%在点注射组织,显示出统计上重要的差别(P<0.01)。在治疗前,在ECP,LPO,CD3+,CD4+,CD4+/CD8+和CD8+的层次没有团体之间的统计上重要的差别,强迫的重要能力(FCV),强迫的吐气的体积1(FEV1),并且山峰吐气的流动(PEF)(P<0.05)。在治疗以后,在观察组的ECP和LPO层次是显著地在另外的二个组比那些减少的更多,显示出统计上重要的差别(P<0.01);在观察组的CD3+,CD4+和CD4+/CD8+的层次显著地被提高,但是CD8+显著地被减少,显示出在另外的二个组的与那些相比的统计上重要的差别(P<0.01);并且在观察组的肺功能索引(FVC,FEV1和PEF)是显著地在另外的二个组比那些提高的更多(P<0.05)。结论联合散布艾灸和点注射能显著地与咳嗽变体气喘在病人减少ECP和LPO的内容,改进细胞的免疫,增加CD3+,CD4+和CD4+/CD8+的内容,减少CD8+的内容并且改进肺功能。