简介：目的：通过多焦视网膜电图（multifocalelectroretinography,mf-ERG）在中心性浆液性脉络膜视网膜病变（centralserouschorioretinopathy,CSC）治疗前后的观察,提高CSC诊断的准确性,并指导临床诊疗,评估预后。方法：设置有比较性的CSC观察组和双眼正常的对照组。观察组有31例CSC患者都是单眼发病,这些患者每只眼（包括患眼与对侧眼）在发病期与恢复期都经过眼科的系统检查,包括最佳矫正视力、眼底荧光血管造影、OCT和mf-ERG,并记录这些检查的数据。对照组有30例,与观察组年龄范围相同,同样做上述检查并记录数据。对两组数据进行对比分析。结果：在CSC发病期,mf-ERG显示患眼平均视网膜振幅密度在1环为60.54±18.20nV/degree2,比对照组（110.94±31.20nV/degree2）低45.43%（P〈0.01）,在2环为38.12±10.81nV/degree2,比对照组（60.91±11.43nV/degree2）低37.42%（P〈0.05）。在恢复期,mf-ERG显示患眼平均视网膜振幅密度在1环为93.71±14.13nV/degree2,比对照组（110.94±31.20nV/degree2）低15.53%（P〈0.05）;在2环为51.16±10.34nV/degree2,比对照组（60.91±11.43nV/degree2）低16.01%（P〈0.05）。另外,我们还发现,观察组31例患者中有8例对侧眼也显示出异常,平均视网膜振幅密度在1环为62.41nV/degree2,其余23例患者对侧眼未发现异常。结论：多焦视网膜电图有助于中心性浆液性脉络膜视网膜病变患者的临床治疗与随访观察,对中心性浆液性脉络膜视网膜病变患者的诊断、病情评估及预后都起着重要的作用。

简介：AIM:ToIntroduceanewspecializedvisualacuitychartforamblyopicchildrenaged3-5yearsoldanditsclinicalapplications.METHODS:ThenewvisualacuitychartandnotationsweredesignedbasedonWeber-Fechnerlaw.Theoptotypeswereredagainstawhitebackgroundandwerespeciallyshapedfourbasicgeometricsymbols:circle,square,triangle,andcross.Aregulargeometricprogressionoftheoptotypesizesanddistributionwasemployedtoarrangein14lines.Theprogressionrateoftheoptotypesizebetweentwolineswas1.2589andthetestingdistancewas3m.VisualacuityscorecouldberecordedaslogMARnotationordecimalnotation.Agestratifieddiagnosticcriteriaforamblyopiaestablishedbyconsensusstatementondiagnosisofamblyopia(2011)amongmembersoftheStrabismusandPediatricOphthalmologyGroup,OphthalmologySociety,ChineseMedicalAssociation(SPOGOSCMA)wereillustratedinthenewvisualacuitychart.RESULTS:Whenassessingvisualacuityinchildrenaged3-5yearsold,thisnewvisualacuitychartthatconsistsoffoursymmetricalshapes(triangle,square,cross,andcircle)overcameaninabilitytorecognizethelettersofthealphabetanddifficultiesindesignatingthedirectionofblackabstractsymbolssuchasthetumbling’E’orLandolt’C’,whichthesubjectswerepronetoloseinterestin.Thevisualacuityscoremayberecordedindifferentnotations:decimalacuityandlogMAR.Thesetwonotationscanbeeasilyconvertedeachotherintheneweyechart.Themeasurementsofthisnewchartnotonlyshowedasignificantcorrelationandagoodconsistencywiththeinternationalstandardlogarithmicvisualacuitychart(r=0.932,P<0.01),butalsoindicatedahightest-retestreliability(89%ofretestscoreswerewithin0.1logMARunitsoftheinitialtestscore).CONCLUSION:Theresultsofthisstudysupportthevalidityandreliabilityofdistancevisualacuitymeasurementsusingtheneweyechartinchildrenaged3to5yearsoverawiderangeofvisualacuities,andtheneweyechartisgreatforearl

简介：AIM:Topresenttheoutcomeofmodifiedgridlaserphotocoagulation(GLP)indiffusediabeticmacularedema(DDME)ineyeswithoutextrafovealand/orvitreofovealtraction.METHODS:InclusioncriteriafortheretrospectivestudywereDDMEeyesofpatientswithtypeⅡdiabetesmellitusthathad≥4monthsoffollow-upfollowingGLP.Onlyoneeyeperpatientwasanalyzed.Using3-Dspectral-domainopticalcoherencetomography(3-DSDOCT),eyesthathadeitherextrafovealorvitreofovealtraction,orhadbeenpreviouslytreatedbyanintravitrealmedication(s)wereexcluded.TreatedDDMEeyesweredividedinto4groups:A)'Classic'DDMEthatinvolvedthecentralmacula;B)edemadidnotinvolvethemacularcenter;C)eyesassociatedwithcentralepiretinalmembrane(ERM);D)DDMEthatwasassociatedwithmacularcapillarydropout≥2disc-diameter(DD).RESULTS:GLPoutcomein35DDMEeyesafter4-24(mean,13.1±6.9)monthswasasfollows:GroupA)18eyeswith'classic'DDME.Followingoneor2(mean,1.2)GLPtreatments,best-correctedvisualacuity(BCVA)improvedby1-2Snellenlinesin44.4%(8/18)ofeyes,andworsenedby1linein11.1%(2/18).Centralmacularthickness(CMT)improvedby7%-49%(mean,26.6%)in77.8%(14/18)ofeyes.CausesofCMTworsening(n=4)werecommonlyexplainable,predominantly(n=3)associatedwithemergenceofextrafovealtraction,5-9monthspost-GLP.GroupB)GLP(s)inDDMEthatdidnotinvolvethemacularcenter(n=6)resultedinimprovedBCVAby1-2linesin2eyes.However,thecentralmaculabecameinvolvedintheedemaprocessaftertheGLPin3(50%)eyes,associatedwithanemergenceofextrafovealtractioninoneoftheseeyes4monthsfollowingtheGLP.GroupC)GLPfailedinall5eyesassociatedwithcentralERM.GroupD)GLPwasofpartialbenefitin2of6treatedeyeswithmacularcapillarydropout≥2DD.CONCLUSION:EyeswithDDMEthatinvolvedthemacularcenterwerefoundtoachievefavourableoutcomesafterGLP(s)duringmid-termfollow-up,unlesscomplicatedpre-GLPorpost-GLPbyvltreoretinalinterfaceabnormalities,oftenextrafovealtra

简介：目的评价甲基纤维素联合透明质酸钠制作软壳技术在白内障小切口非超声乳化手术中的效果.方法白内障“复明工程”患者261例295眼.随机分为A、B两组,其中A组术中单用透明质酸钠,B组术中联合使用甲基纤维素和透明质酸钠.手术方法为小切口非超声乳化加人工晶体植入.结果术后第ld裸眼视力大于0.3者,A组78.79％（104/132）,B组87.1％（142/163）,两组之间差异显著（P＜0.05）；术后第7d视力在0.3以上者,A组93.9％（124/132）,B组94.5％（154/163）.两组间差异无统计学意义（P＞0.05）.术后角膜水肿情况：术后第1天,A组17.42％（23/132）,B组9.8％（16/163）,两组间比较差异有统计学意义（P＜0.05）.术后第7天,A组2.27％（3/132）,B组2.45％（4/163）,两组间比较差异无统计学意义（P＞0.05）.结论甲基纤维素联合透明质酸钠制作软壳技术比单用透明质酸钠更安全.