摘要
[摘要 ] 目的 探讨有创呼吸机、无创呼吸机序贯治疗重症慢阻肺 II型呼吸衰竭的临床疗效。方法 方便择取该院 2018年 1月— 2020年 1月期间收治的 52例重症慢阻肺 II型呼吸衰竭患者为研究对象，按照前瞻性方式将 52例患者随机分为对照组和观察组，每组 26例。对照组给予间歇指令通气加压通气，观察组患者采用有创和无创序贯通气治疗。治疗结束后，评价两组患者的治疗效果。结果 观察组脱机时间（ 4.2±1.20） d，对照组脱机时间（ 5.8±1.40） d，差异有统计学意义（ t=4.336 9， P<0.05）。两组患者治疗后血气指标各项值均较治疗前有显著改善，治疗后对照组患者各项指标稍优于观察组，但比较差异无统计学意义（ P>0.05）。同时，从不良反应发生率上来看，观察组 7.69%显著低于对照组 19.23%，差异有统计学意义（ χ2=5.716 4， P<0.05）。结论 针对重症慢阻肺 II型呼吸衰竭患者可给予有创和无创呼吸机序贯治疗的方式，改善患者血气指标，缩短脱机时间，患者耐受性好，提高治疗效果，值得推广。
[关键词 ] 有创呼吸机；无创呼吸机；序贯治疗；重症慢阻肺 II型呼吸衰竭
[Abstract] Objective To explore the clinical effect of sequential treatment of severe COPD type II respiratory failure with invasive ventilator and noninvasive ventilator. Methods 52 patients with severe COPD type II respiratory failure admitted in our hospital from January 2018 to January 2020 were selected as the study objects. According to the prospective way, 52 patients were randomly divided into control group and observation group, each group had 26 cases. The patients in the observation group were treated with invasive and noninvasive sequential ventilation. After the treatment, the therapeutic effect of the two groups was evaluated. Results the difference was statistically significant (t = 4.3369, P < 0.05). After treatment, the blood gas indexes of the two groups were significantly improved compared with those before treatment. After treatment, the indexes of the control group were slightly better than those of the observation group, but the difference was not statistically significant (P > 0.05). At the same time, in terms of the incidence of adverse reactions, 7.69% in the observation group was significantly lower than 19.23% in the control group, the difference was statistically significant (χ 2 = 5.7164, P < 0.05). Conclusion for the patients with severe COPD type II respiratory failure, the sequential treatment of invasive and non-invasive ventilator can be given to improve the blood gas index of patients, shorten the time of weaning, improve the tolerance of patients, and improve the treatment effect, which is worth popularizing.
出版日期
2020年08月18日（中国期刊网平台首次上网日期，不代表论文的发表时间）
